DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5880 and zdhhc2

DIOPT Version :9

Sequence 1:	NP_651539.3	Gene:	CG5880 / 43268	FlyBaseID:	FBgn0039489	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	XP_021336686.1	Gene:	zdhhc2 / 541365	ZFINID:	ZDB-GENE-050320-58	Length:	374	Species:	Danio rerio

Alignment Length:	358	Identity:	90/358 - (25%)
Similarity:	144/358 - (40%)	Gaps:	109/358 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 IAYWIGLPF------WWAKSQLV-------------TYFLLIVGNWLLLNVVFHYVMAVITPAGH 125
            :.|||.:.|      |...:.:|             |.:|||. :.|.|..|:.|...:.:...:
Zfish    14 VLYWIPVLFISLIVAWSYYAYVVQLCIETIENMGEKTVYLLIY-HLLFLMFVWSYWQTIYSKPMN 77

  Fly   126 PPEGVSLVE-----------------------------------AVSMCGKCIAPKPPRTHHCSI 155
            |.:...|..                                   |:..|.:|:..||.|.||||.
Zfish    78 PLKEFHLSHVDKELLEREDRRESQQEILRRIAKDLPIYTRTMSGAIRYCDRCLLLKPDRCHHCSA 142

  Fly   156 CNRCILKMDHHCPWLNNCVGYGNHRYFFLYMTYTTLGCLFLILFGLEIGHKYLWLDHGENWTEIE 220
            |:.|||||||||||:|||||:.|:::|.|::.|:.|.|||:....::...::        ||
Zfish   143 CDMCILKMDHHCPWVNNCVGFANYKFFMLFLAYSLLYCLFVTATDMQYFIQF--------WT--- 196

  Fly   221 PLEGQPVKFNLSGHIIPVTHPNEYDEFVLPPAVHNLPTPIVDTDAASPGRRRALWFMAFTNVAVV 285
             ::|:             ||..      |...::.||    ||.|     :..:.|:.|......
Zfish   197 -VDGK-------------THDR------LIQYLNGLP----DTQA-----KFHIMFLFFAASTFS 232

  Fly   286 LALGSLSIWHAKLITRGETSVEAHINEAERKRHLQQQRIYINPYNFGTKKNWKLFLGLVRGRSFW 350
            ::|..|..:|..|:.:..:::||.  .|...:|...:    |.::.|..||::...|  ..:.:|
Zfish   233 VSLAFLFAYHCWLVCKNRSTLEAF--RAPAFQHGTDK----NGFSLGAYKNFRQVFG--DEKKYW 289

  Fly   351 RTVLLPSWHKPEGTGLSFHT--VNDAPFEDEWP 381
               |||.: ...|.|.||.|  ||..|.:...|
Zfish   290 ---LLPIF-SSLGDGCSFPTCLVNPDPEQPSIP 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	zf-DHHC	139..>201	CDD:279823	34/61 (56%)
zdhhc2	XP_021336686.1	zf-DHHC	11..305	CDD:327686	85/343 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55511
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.830