DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5880 and zdhhc16b

DIOPT Version :9

Sequence 1:	NP_651539.3	Gene:	CG5880 / 43268	FlyBaseID:	FBgn0039489	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	XP_009304660.1	Gene:	zdhhc16b / 393316	ZFINID:	ZDB-GENE-040426-1301	Length:	382	Species:	Danio rerio

Alignment Length:	389	Identity:	159/389 - (40%)
Similarity:	207/389 - (53%)	Gaps:	60/389 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RGHSTQELLSILRLRWSYMKHCWHSLTFNAHMNSSYASDVCLTPIFWFVDNYTHCLGPFFVVGVA 71
            |||..:   |.:|..|:|......||.:|...||....|....||:|.|||.|...|..||..|.
Zfish    25 RGHRKR---SRVRDLWNYGMVVLKSLYYNVQTNSDTVLDCMFEPIYWLVDNMTRWFGVVFVCLVM 86

  Fly    72 ALTTSVVSIAYWIGLPFWWAKSQLVTYFL---LIVGNWLLLNVVFHYVMAVITPAGHPPEGVSLV 133
            |||:|||.|.|...||..:  |....|::   |..|:|.||.|||||..|..|..|.||:..:.:
Zfish    87 ALTSSVVVIVYLCVLPIIF--SSYPVYWILWHLCYGHWNLLMVVFHYYKATTTQPGFPPQEKTDI 149

  Fly   134 EAVSMCGKCIAPKPPRTHHCSICNRCILKMDHHCPWLNNCVGYGNHRYFFLYMTYTTLGCLFLIL 198
            ..|::|.|||.|||.|||||||||||||||||||||||||||:.||||||.:..:.|:||::
Zfish   150 PTVTICKKCIVPKPARTHHCSICNRCILKMDHHCPWLNNCVGHFNHRYFFSFCLFMTMGCVY--- 211

  Fly   199 FGLEIGHKYLWLDHGENWTEIEPLEGQPVKFNLS-GHIIP--------VTHPNEYDEFVLPPA-- 252
              ..|..|.::||      ....:|....|...| |..:|        ..|.:.|.  ..|||
Zfish   212 --CSISAKDMFLD------AYNAIESGRYKGGASQGEAVPGAGLIYISFQHQSSYQ--TPPPAFT 266

  Fly   253 -----VHNLPTPIVDTDAASPGRRRALWFMAFTNVAVVLALGSLSIWHAKLITRGETSVEAHINE 312
                 ||                 ::|.::.....:|.:|||:|::|||.||||||||||.|||.
Zfish   267 HQERMVH-----------------KSLVYLWVLTSSVAVALGALTLWHAILITRGETSVERHINR 314

  Fly   313 AERKRHLQQQRIYINPYNFGTKKNWKLFLGLVRGRSF-WRTVLLPSWHKPEGTGLSFHTVNDAP 375
            .||:|...:.:::.|||:.|...||::|.|:.:|..: || |||||.|.|.|.||::    |.|
Zfish   315 KERRRLKLRGKLFRNPYHHGRINNWRIFFGVEKGSDWLWR-VLLPSTHPPLGDGLTW----DCP 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	zf-DHHC	139..>201	CDD:279823	43/61 (70%)
zdhhc16b	XP_009304660.1	zf-DHHC	83..>206	CDD:327686	69/124 (56%)
zdhhc16b	XP_009304660.1	zf-DHHC	154..310	CDD:307600	77/185 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586919
Domainoid	1	1.000	138	1.000	Domainoid score	I4804
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I3089
OMA	1	1.010	-	-		QHG55511
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	1	1.000	-	-		FOG0005702
OrthoInspector	1	1.000	-	-		otm25493
orthoMCL	1	0.900	-	-		OOG6_103703
Panther	1	1.100	-	-	O	PTHR12246
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4100
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.810