DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5880 and Zdhhc13

DIOPT Version :9

Sequence 1:	NP_651539.3	Gene:	CG5880 / 43268	FlyBaseID:	FBgn0039489	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001382044.1	Gene:	Zdhhc13 / 365252	RGDID:	1309736	Length:	622	Species:	Rattus norvegicus

Alignment Length:	393	Identity:	85/393 - (21%)
Similarity:	133/393 - (33%)	Gaps:	148/393 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 WSYMKHC-------------W---HSLTFNAHMNSSYASDVCLTPIFWFVDNYTHCLGPFFVVGV 70
            |.::..|             |   :.|.||   :.|:....||.....|:.:    |.|.|:||.
  Rat   284 WQWLHKCELFLLLVLSMISLWAVGYILNFN---SDSWLLKGCLLVALLFLTS----LFPRFLVGY 341

  Fly    71 AAL----TTSVVSIAYWI-------------GLPFWWAKSQLVTYFLLIVGNWLLLNVVFHYVMA 118
            ..|    |..::|..:||             |.||::|....:..||..          |:...|
  Rat   342 KNLVYLPTVFLLSSIFWIFMTWFILFFPDAAGSPFYFAFIFSIMAFLYF----------FYKTWA 396

  Fly   119 V---ITPAGHPPEGVSLVEAV--------SMCGKCIAPKPPRTHHCSICNRCILKMDHHCPWLNN 172
            .   .|.|......|::|...        :.|..|:..||.|:.||.:||.|:.:.|.||.|...
  Rat   397 TDPGFTKASEEERKVNIVTLAETGSLDFRTFCTSCLIRKPLRSLHCHVCNSCVARFDQHCFWTGR 461

  Fly   173 CVGYGNHRYFFLYMTYTTLGCLFLILFGLEIGHKYLWLDHGEN-------WTEIEPLEGQPVKFN 230
            |:|:|||.::..::...::.|.::|     .|....|.:|...       ||.:..:.
  Rat   462 CIGFGNHHHYIFFLLSLSMVCDWII-----YGSFVYWSNHCATTFKEDGLWTYLNQIV------- 514

  Fly   231 LSGHIIPVTHPNEYDEFVLPPAVHNLPTPIVDTDAASPGRRRALWFMAFTNVAVVLALGSLSIWH 295
                                              |.||      |         ||.:..|:.:|
  Rat   515 ----------------------------------ACSP------W---------VLYIFMLAAFH 530

  Fly   296 AK-----LITR-------GETSVEAHINEAERKRHLQQQ-RIYINPYNFGTKKNWKLF-----LG 342
            ..     ||.:       |.||.| .|:..::.||::|. .:...|||.|..:|...|     .|
  Rat   531 FSWSTFLLINQLFQIAFLGLTSHE-RISLLKQSRHMKQTLSLRKTPYNLGFMQNLADFFQCGCFG 594

  Fly   343 LVR 345
            ||:
  Rat   595 LVK 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	zf-DHHC	139..>201	CDD:279823	21/61 (34%)
Zdhhc13	NP_001382044.1	Ank_2	66..>269	CDD:423045
		ANK repeat	81..112	CDD:293786
		ANK repeat	114..146	CDD:293786
		ANK repeat	148..179	CDD:293786
		ANK repeat	181..247	CDD:293786
		DHHC	423..557	CDD:396215	40/195 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000