DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5880 and Zdhhc6

DIOPT Version :9

Sequence 1:	NP_651539.3	Gene:	CG5880 / 43268	FlyBaseID:	FBgn0039489	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001032741.1	Gene:	Zdhhc6 / 361771	RGDID:	1304657	Length:	413	Species:	Rattus norvegicus

Alignment Length:	343	Identity:	101/343 - (29%)
Similarity:	147/343 - (42%)	Gaps:	99/343 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 GPFFVVGVAAL--TTSVVSIAYWIGLPFW--WAKSQLVTYFLLIVGNWLLLNVVFHYVMAV---- 119
            ||...:||.|:  |.:::....|    :|  ......|.:.:||  ||.:: ::::|..|:
  Rat    23 GPIIALGVIAICSTMAMIDSVLW----YWPLHTTGGSVNFIMLI--NWTVM-ILYNYFNAMFAGP 80

  Fly   120 -ITPAGHPPEGVSLVEAVSMCGKCIAPKPPRTHHCSICNRCILKMDHHCPWLNNCVGYGNHRYFF 183
             ..|.|..||.......:..|..|.|.|.||:|||..||||::||||||||:|||.|:.||..|.
  Rat    81 GFVPRGWKPENPQDSMYLQYCKVCQAYKAPRSHHCRKCNRCVMKMDHHCPWINNCCGHQNHASFT 145

  Fly   184 LYMTYTTLGC-----LFLILFGLEIGHKYLWLDHGENWTEIEPLEGQPVKFNLSGHIIPVTHPNE 243
            |::....|||     :|::....::   |..|..|.|          .||.::|
  Rat   146 LFLLLAPLGCTHAAFIFVMTMYTQL---YNRLSFGWN----------TVKIDMS----------- 186

  Fly   244 YDEFVLPPAVHNLPTPIVDTDAASPGRRRALWFMAFTNVAVVLALGS------LSIWHAKLITRG 302
                    |....|.|||....|:         .|.|..|:.||||:      |.....|:|.|.
  Rat   187 --------AARRDPPPIVPFGLAA---------FAATLFALGLALGTTIAVGMLFFIQIKIILRN 234

  Fly   303 ETSVEAHINE--AERKRHLQQQRIYINPYNFGTK-KNWK-LFLGLVRGRSFWRTVLLPSWHKPEG 363
            :||:|:.|.|  .:|.::.|...:::.||:.|:| ||.| :|.        |..|       |||
  Rat   235 KTSIESWIEEKAKDRIQYYQLDEVFVFPYDMGSKWKNLKQVFT--------WSGV-------PEG 284

  Fly   364 TGLSFHTVNDAPFEDEWP 381
            .||            |||
  Rat   285 DGL------------EWP 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	zf-DHHC	139..>201	CDD:279823	33/66 (50%)
Zdhhc6	NP_001032741.1	DHHC	95..241	CDD:396215	60/186 (32%)
Zdhhc6	NP_001032741.1	SH3_2	317..394	CDD:400139
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820