DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5880 and zdhhc6

DIOPT Version :9

Sequence 1:	NP_651539.3	Gene:	CG5880 / 43268	FlyBaseID:	FBgn0039489	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001191086.1	Gene:	zdhhc6 / 324468	ZFINID:	ZDB-GENE-030131-3189	Length:	412	Species:	Danio rerio

Alignment Length:	333	Identity:	90/333 - (27%)
Similarity:	143/333 - (42%)	Gaps:	79/333 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 GPFF---VVGVAALTTSVVSIAYWIGLPFWW---AKSQLVTYFLLIVGNWLLLNVVFHYVMAVIT 121
            ||..   |:||.:      |:|....:.::|   .....:.:.:||  ||.:| ::::|..|:..
Zfish    23 GPIIALTVIGVCS------SMAILDSIIWYWPLDTTGGSINFIMLI--NWTVL-ILYNYFNAMFV 78

  Fly   122 PAGH-----PPEGVSLVEAVSMCGKCIAPKPPRTHHCSICNRCILKMDHHCPWLNNCVGYGNHRY 181
            ..|:     .||....:..:..|..|...|.||:|||..||||::||||||||:|||.|:.||.|
Zfish    79 GPGYIPLEWKPEKQQDIMYLQFCRLCQGYKAPRSHHCRKCNRCVMKMDHHCPWINNCCGHLNHAY 143

  Fly   182 FFLYMTYTTLGCLFLILFGLEIGHKYLWLDHGENWTEIEPLEGQPVKFNLSGHIIPVTHPNEYDE 246
            |..::....|||:...|..:...:..|:......|:.::      :..:.:.||   .||
Zfish   144 FTSFLLLAPLGCIHAALIFIMTMYTQLYDRISFGWSSVK------IDMSAARHI---HHP----- 194

  Fly   247 FVLPPAVHNLPTPIVDTDAASPGRRRALWFMAFTNVAVVLALGSLSIWHAKLITRGETSVEAHIN 311
             ::|.::           ||......||.....|.:||    |.|.....|:|.|..||:||.|.
Zfish   195 -IMPFSI-----------AAFAATLFALGLALGTTIAV----GMLFFIQMKVILRNRTSIEAWIE 243

  Fly   312 E--AERKRHLQQQRIYINPYNFGTKKNWKLFLGLVRGRSFWRTVLLPSWH-KPEGTGLSFHTVND 373
            |  .:|.::.|....:|.||:.|::  |:.|..:.            :|. .|.|.|:
Zfish   244 EKAKDRIQYYQTGEDFIFPYDLGSR--WENFKQVF------------TWSGAPMGDGI------- 287

  Fly   374 APFEDEWP 381
                 |||
Zfish   288 -----EWP 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	zf-DHHC	139..>201	CDD:279823	32/61 (52%)
zdhhc6	NP_001191086.1	DHHC	95..241	CDD:396215	54/175 (31%)
zdhhc6	NP_001191086.1	Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9H6R6	409..412
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820