DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5880 and Zdhhc22

DIOPT Version :9

Sequence 1:	NP_651539.3	Gene:	CG5880 / 43268	FlyBaseID:	FBgn0039489	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001034414.1	Gene:	Zdhhc22 / 299211	RGDID:	1308446	Length:	263	Species:	Rattus norvegicus

Alignment Length:	246	Identity:	64/246 - (26%)
Similarity:	96/246 - (39%)	Gaps:	61/246 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 WLLLNVVFHYVMAVITPAGHPPEGVSLVEAVSMCGKCIAPK--PPRTHHCSICNRCILKMDHHCP 168
            :|..|.:.:|::.|    .:.|:.:...:..|    ...|:  ||.||.|.:|.|..|:.||||.
  Rat    56 FLSANALGNYILVV----QNSPDDLGACQGTS----SQRPQRPPPSTHFCRVCARVTLRHDHHCF 112

  Fly   169 WLNNCVGYGNHRYFFLYMTYTTLGCLFLILFGLEIGHKYLWLDHGENWTEIEPLEGQPVKFNLSG 233
            :..||:|..|.|.|.|:..||:|.||:.::.|:..                       :...||
  Rat   113 FTGNCIGSRNMRNFILFCLYTSLACLYSMVAGVAY-----------------------ISAVLS- 153

  Fly   234 HIIPVTHPNEYDEFVLPPAVHNLPTPIVD-TDAASPGRRRALWFMAFTNVAVVLALGSLSIWHAK 297
              |...||..:        :..|||.|.. ...|..|....:..|.:...||.||..........
  Rat   154 --ISFAHPLAF--------LTLLPTSISQFFSGAVLGSDMFVILMLYLWFAVGLACAGFCCHQLL 208

  Fly   298 LITRGETSVEAHINEAER----KRHLQQQRIYINPYNFGTKKNWKLFLGLV 344
            ||.||:|..:.....|.|    :::||:.        ||  |.|  .|||:
  Rat   209 LILRGQTRYQVRKGVAVRARPWRKNLQEV--------FG--KRW--LLGLL 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	zf-DHHC	139..>201	CDD:279823	25/63 (40%)
Zdhhc22	NP_001034414.1	DHHC	91..218	CDD:396215	46/160 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810