DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5880 and ZDHHC5

DIOPT Version :9

Sequence 1:NP_651539.3 Gene:CG5880 / 43268 FlyBaseID:FBgn0039489 Length:381 Species:Drosophila melanogaster
Sequence 2:NP_056272.2 Gene:ZDHHC5 / 25921 HGNCID:18472 Length:715 Species:Homo sapiens


Alignment Length:334 Identity:79/334 - (23%)
Similarity:118/334 - (35%) Gaps:121/334 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    66 FVVGVA----ALTTSVVSIAYWIGLPFWWAKSQLVTYFLLIVGNWLLLNVVFHYVMAVITPAGHP 126
            |:||..    |.|...:|:.....:|.:.|     ..||.::.|         :.||.....|..
Human    23 FLVGATTLFFAFTCPGLSLYVSPAVPIYNA-----IMFLFVLAN---------FSMATFMDPGIF 73

  Fly   127 P----------------------EGVSLVEAVSMCGKCIAPKPPRTHHCSICNRCILKMDHHCPW 169
            |                      :|:.:  .:..|..|...:|||..|||:|:.|:.:.||||||
Human    74 PRAEEDEDKEDDFRAPLYKTVEIKGIQV--RMKWCATCRFYRPPRCSHCSVCDNCVEEFDHHCPW 136

  Fly   170 LNNCVGYGNHRYFFLYMTYTTLGCLFLILFGLEIGHKYLWLDHGENWTEIEPLEGQPVKFNLSGH 234
            :|||:|..|:|||||::...|...:.:..|||    .|: |.|.|               .|||.
Human   137 VNNCIGRRNYRYFFLFLLSLTAHIMGVFGFGL----LYV-LYHIE---------------ELSGV 181

  Fly   235 IIPVTHPNEYDEFVLPPAVHNLPTPIVDTDAASPGRRRALWFMAFTNVA--VVLALGSLSIWHAK 297
            ...||                                     ||...||  ..:.:..|:.:|..
Human   182 RTAVT-------------------------------------MAVMCVAGLFFIPVAGLTGFHVV 209

  Fly   298 LITRGETSVEAHINEAERKRHLQQQRIYINPYNFGTKKNWK---------LFLGLVRGRSFWRTV 353
            |:.||.|:     ||....:.    |..:||:..|...|..         .:||  |.:.....|
Human   210 LVARGRTT-----NEQVTGKF----RGGVNPFTNGCCNNVSRVLCSSPAPRYLG--RPKKEKTIV 263

  Fly   354 LLPSWHKPE 362
            :.|.:.:||
Human   264 IRPPFLRPE 272

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5880NP_651539.3 zf-DHHC 139..>201 CDD:279823 28/61 (46%)
ZDHHC5NP_056272.2 DHHC 99..224 CDD:366691 51/188 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 289..715
DUF4671 594..>704 CDD:374041
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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