Protein Alignment CG5880 and ZDHHC5

DIOPT Version :10

• Sequence 1: NP_651539.3
• Gene: CG5880 / 43268
• FlyBaseID: FBgn0039489
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_056272.2
• Gene: ZDHHC5 / 25921
• HGNCID: 18472
• Length: 715
• Species: Homo sapiens
• Alignment Length: 334
• Identity: 79/334 - (23%)
• Similarity: 118/334 - (35%)
• Gaps: 121/334 - (36%)

  Fly    66 FVVGVA----ALTTSVVSIAYWIGLPFWWAKSQLVTYFLLIVGNWLLLNVVFHYVMAVITPAGHP 126
            |:||..    |.|...:|:.....:|.:.|     ..||.::.|         :.||.....|..
Human    23 FLVGATTLFFAFTCPGLSLYVSPAVPIYNA-----IMFLFVLAN---------FSMATFMDPGIF 73

  Fly   127 P----------------------EGVSLVEAVSMCGKCIAPKPPRTHHCSICNRCILKMDHHCPW 169
            |                      :|:.:  .:..|..|...:|||..|||:|:.|:.:.||||||
Human    74 PRAEEDEDKEDDFRAPLYKTVEIKGIQV--RMKWCATCRFYRPPRCSHCSVCDNCVEEFDHHCPW 136

  Fly   170 LNNCVGYGNHRYFFLYMTYTTLGCLFLILFGLEIGHKYLWLDHGENWTEIEPLEGQPVKFNLSGH 234
            :|||:|..|:|||||::...|...:.:..|||    .|: |.|.|               .|||.
Human   137 VNNCIGRRNYRYFFLFLLSLTAHIMGVFGFGL----LYV-LYHIE---------------ELSGV 181

  Fly   235 IIPVTHPNEYDEFVLPPAVHNLPTPIVDTDAASPGRRRALWFMAFTNVA--VVLALGSLSIWHAK 297
            ...||                                     ||...||  ..:.:..|:.:|..
Human   182 RTAVT-------------------------------------MAVMCVAGLFFIPVAGLTGFHVV 209

  Fly   298 LITRGETSVEAHINEAERKRHLQQQRIYINPYNFGTKKNWK---------LFLGLVRGRSFWRTV 353
            |:.||.|:     ||....:.    |..:||:..|...|..         .:||  |.:.....|
Human   210 LVARGRTT-----NEQVTGKF----RGGVNPFTNGCCNNVSRVLCSSPAPRYLG--RPKKEKTIV 263

  Fly   354 LLPSWHKPE 362
            :.|.:.:||
Human   264 IRPPFLRPE 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	DHHC	139..>201	CDD:396215	28/61 (46%)
ZDHHC5	NP_056272.2	DHHC	99..224	CDD:396215	51/188 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	289..715