Protein Alignment CG5880 and ZDHHC23

DIOPT Version :9

• Sequence 1: NP_651539.3
• Gene: CG5880 / 43268
• FlyBaseID: FBgn0039489
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_001307395.1
• Gene: ZDHHC23 / 254887
• HGNCID: 28654
• Length: 435
• Species: Homo sapiens
• Alignment Length: 453
• Identity: 92/453 - (20%)
• Similarity: 144/453 - (31%)
• Gaps: 188/453 - (41%)

  Fly    18 LRLRWSYMKHCWHSLTFNAHMNSSYASDVCLTPIFWFVDNYTHCLGPFFVVGVAALTTSVVSIAY 82
            ||:.|         |.....:|.|....:.|.|:|..|.::      .|::||..| ||:..:|.
Human    77 LRIPW---------LRGAKKVNISIIPPLVLLPVFLHVASW------HFLLGVVVL-TSLPVLAL 125

  Fly    83 WIGLPFWWAKSQLVTYFLLIVGNWLLLNVVFHYV-------------MAVIT------------- 121
            |........|.|  |.|.|.:|.:.|..:.:.::             :||:|
Human   126 WYYYLTHRRKEQ--TLFFLSLGLFSLGYMYYVFLQEVVPKGRVGPVQLAVLTCGLFLILLALHRA 188

  Fly   122 ---------PA-----------------------GHP----------------PEGVSLVEAVS- 137
                     ||                       |.|                |:|.|.:.|.|
Human   189 KKNPGYLSNPASGDRSLSSSQLECLSRKGQEKTKGFPGADMSGSLNNRTTKDDPKGSSKMPAGSP 253

  Fly   138 ------MCGKCIAPKPPRTHHCSICNRCILKMDHHCPWLNNCVGYGNHRYFFLYMTYTTLGCLFL 196
                  .|.||...:|.|..||.||..|:.:|||||.|:|:|||..||:.|.|.:      .:||
Human   254 TKAKEDWCAKCQLVRPARAWHCRICGICVRRMDHHCVWINSCVGESNHQAFILAL------LIFL 312

  Fly   197 I--LFGLEIGHKYLWLDHGENWTEIEPLEGQPVKFNLSGHIIPVTHPNEYDEFVLPPAVHNLPTP 259
            :  ::|:                                                        |.
Human   313 LTSVYGI--------------------------------------------------------TL 321

  Fly   260 IVDTDAASPGRRRALWFMAFTNVAVVLALGSLSIWHAKLITRGET--------SVEAHINEAERK 316
            .:||.........||::..........||....:|::.:||.|..        ::..::.|.|.:
Human   322 TLDTICRDRSVFTALFYCPGVYANYSSALSFTCVWYSVIITAGMAYIFLIQLINISYNVTEREVQ 386

  Fly   317 RHLQQQRIYINPYNFGTKKNWKLFLGLVRGRSFWRTVLLPSWHKPEGTGL-SFHTVNDAPFED 378
            :.|:|            |...:|..||:.....:....|.:||:....|. :||    .|.||
Human   387 QALRQ------------KTGRRLLCGLIVDTGQYNRGFLRNWHQFSTLGTRAFH----HPAED 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	zf-DHHC	139..>201	CDD:279823	26/63 (41%)
ZDHHC23	NP_001307395.1	MerC	96..>151	CDD:281231	19/63 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	215..255		7/39 (18%)
		zf-DHHC	258..384	CDD:279823	39/187 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810