DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5880 and Zdhhc5

DIOPT Version :9

Sequence 1:	NP_651539.3	Gene:	CG5880 / 43268	FlyBaseID:	FBgn0039489	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_659136.1	Gene:	Zdhhc5 / 228136	MGIID:	1923573	Length:	715	Species:	Mus musculus

Alignment Length:	334	Identity:	79/334 - (23%)
Similarity:	118/334 - (35%)	Gaps:	121/334 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 FVVGVA----ALTTSVVSIAYWIGLPFWWAKSQLVTYFLLIVGNWLLLNVVFHYVMAVITPAGHP 126
            |:||..    |.|...:|:.....:|.:.|     ..||.::.|         :.||.....|..
Mouse    23 FLVGATTLFFAFTCPGLSLNVSPAVPIYNA-----IMFLFVLAN---------FSMATFMDPGIF 73

  Fly   127 P----------------------EGVSLVEAVSMCGKCIAPKPPRTHHCSICNRCILKMDHHCPW 169
            |                      :|:.:  .:..|..|...:|||..|||:|:.|:.:.||||||
Mouse    74 PRAEEDEDKEDDFRAPLYKTVEIKGIQV--RMKWCATCRFYRPPRCSHCSVCDNCVEEFDHHCPW 136

  Fly   170 LNNCVGYGNHRYFFLYMTYTTLGCLFLILFGLEIGHKYLWLDHGENWTEIEPLEGQPVKFNLSGH 234
            :|||:|..|:|||||::...|...:.:..|||    .|: |.|.|               .|||.
Mouse   137 VNNCIGRRNYRYFFLFLLSLTAHIMGVFGFGL----LYV-LYHIE---------------ELSGV 181

  Fly   235 IIPVTHPNEYDEFVLPPAVHNLPTPIVDTDAASPGRRRALWFMAFTNVA--VVLALGSLSIWHAK 297
            ...||                                     ||...||  ..:.:..|:.:|..
Mouse   182 RTAVT-------------------------------------MAVMCVAGLFFIPVAGLTGFHVV 209

  Fly   298 LITRGETSVEAHINEAERKRHLQQQRIYINPYNFGTKKNWK---------LFLGLVRGRSFWRTV 353
            |:.||.|:     ||....:.    |..:||:..|...|..         .:||  |.:.....|
Mouse   210 LVARGRTT-----NEQVTGKF----RGGVNPFTNGCCNNVSRVLCSSPAPRYLG--RPKKEKTIV 263

  Fly   354 LLPSWHKPE 362
            :.|.:.:||
Mouse   264 IRPPFLRPE 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	zf-DHHC	139..>201	CDD:279823	28/61 (46%)
Zdhhc5	NP_659136.1	zf-DHHC	99..224	CDD:279823	51/188 (27%)
Zdhhc5	NP_659136.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	289..715
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810