DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5880 and Zdhhc14

DIOPT Version :9

Sequence 1:	NP_651539.3	Gene:	CG5880 / 43268	FlyBaseID:	FBgn0039489	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_666185.3	Gene:	Zdhhc14 / 224454	MGIID:	2653229	Length:	489	Species:	Mus musculus

Alignment Length:	312	Identity:	66/312 - (21%)
Similarity:	114/312 - (36%)	Gaps:	110/312 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 GPFFVVGVAALTTSVVSIAY---WIGLPFWWAKSQLVTYFLLIVGNWLLLNVVFHYVMAV----- 119
            |.|::..:..|.||.:..|:   ::        ::.:|..:.:||     .::|.:||..
Mouse    62 GVFYLTLILILVTSGLFFAFDCRYL--------AEKITPAIPVVG-----GILFFFVMGTLLRTS 113

  Fly   120 -----ITPAGHPPEGVSLVEAVSM-----------------------------CGKCIAPKPPRT 150
                 :.|...|.|...|...:.:                             |..|...:|||.
Mouse   114 FSDPGVLPRATPDEAADLERQIDIANGTSSGGYRPPPRTKEVVINGQTVKLKYCFTCKIFRPPRA 178

  Fly   151 HHCSICNRCILKMDHHCPWLNNCVGYGNHRYFFLYMTYTTLGCLFLILFGLEIGHKYLWLDHGEN 215
            .|||:|:.|:.:.||||||:.||||..|:|:|  ||...:|..|.:.:|...|.|
Mouse   179 SHCSLCDNCVEQFDHHCPWVGNCVGKRNYRFF--YMFILSLSFLTVFIFAFVITH---------- 231

  Fly   216 WTEIEPLEGQPVKFNLSGHIIPVTHPNEYDEFVLPPAVHNLPTPIVDTDAASPGRRRALWFMAFT 280
                                  |.|.::...|:  .|:.:.|..:::.            .:.|.
Mouse   232 ----------------------VIHRSQQKGFL--DALKDSPASVLEA------------VICFF 260

  Fly   281 NVAVVLALGSLSIWHAKLITRGETSVEAHINEAERKRHLQQQRIYINPYNFG 332
            :|..::   .||.:|..||:..:|:.|........||..:.    .|||::|
Mouse   261 SVWSII---GLSGFHTYLISSNQTTNEDIKGSWSNKRGKEN----YNPYSYG 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	zf-DHHC	139..>201	CDD:279823	28/61 (46%)
Zdhhc14	NP_666185.3	zf-DHHC	164..289	CDD:307600	44/175 (25%)
Zdhhc14	NP_666185.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	434..454
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810