DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5880 and zdhhc17

DIOPT Version :9

Sequence 1:	NP_651539.3	Gene:	CG5880 / 43268	FlyBaseID:	FBgn0039489	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001121854.1	Gene:	zdhhc17 / 100148543	ZFINID:	ZDB-GENE-070424-194	Length:	620	Species:	Danio rerio

Alignment Length:	229	Identity:	61/229 - (26%)
Similarity:	87/229 - (37%)	Gaps:	79/229 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTRITWRGHSTQELLSILRLRWSYMKHCWHS-LTFNAHMNSSYASDVCLTPIFWFVDNYTHCLGP 64
            |..:.|        |.:..|..|:..|..|| |....::.:.:.  :.:|..:||
Zfish   322 MYAVMW--------LVVQFLSKSFFDHSMHSALPLGIYLATKFW--MYITWFYWF---------- 366

  Fly    65 FFVVGVAALTTSVVSIAYWIGLPFWWAKSQLVTYFLLIVGNWLLLNVVFHYVMAV-------ITP 122
                              |..|||       ||..|    .:||.::...|....       |..
Zfish   367 ------------------WNDLPF-------VTIHL----PFLLNSLALFYNFGKSWKSDPGIIK 402

  Fly   123 AGHPPEGVSLVEAVS--------MCGKCIAPKPPRTHHCSICNRCILKMDHHCPWLNNCVGYGNH 179
            |....:..::||...        .|..|:..||.|:.||::|||||.|.||||||:.||||.|||
Zfish   403 ASEEQKKKTIVELAETGSLDLSIFCSTCLIRKPIRSKHCAVCNRCIAKFDHHCPWVGNCVGSGNH 467

  Fly   180 RYFFLYMTYTTLGCLFLILFGLEIGHKYLWLDHG 213
            |||        :|.||.:|..:      .|:.:|
Zfish   468 RYF--------MGYLFFLLCMI------CWMMYG 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	zf-DHHC	139..>201	CDD:279823	33/61 (54%)
zdhhc17	NP_001121854.1	PHA02874	<59..>253	CDD:165205
		ANK repeat	77..108	CDD:293786
		ANK 1. /evidence=ECO:0000255	77..106
		ANK repeat	110..142	CDD:293786
		ANK 2. /evidence=ECO:0000255	111..140
		ANK repeat	144..175	CDD:293786
		ANK 3. /evidence=ECO:0000255	144..173
		Ank_2	150..243	CDD:403870
		ANK repeat	177..209	CDD:293786
		ANK 4. /evidence=ECO:0000255	177..207
		ANK repeat	212..243	CDD:293786
		ANK 5. /evidence=ECO:0000255	212..241
		ANK 6. /evidence=ECO:0000255	245..274
		DHHC	426..556	CDD:396215	35/76 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810