DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5880 and zdhhc20b

DIOPT Version :9

Sequence 1:	NP_651539.3	Gene:	CG5880 / 43268	FlyBaseID:	FBgn0039489	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	XP_005162815.2	Gene:	zdhhc20b / 100001188	ZFINID:	ZDB-GENE-091117-30	Length:	409	Species:	Danio rerio

Alignment Length:	343	Identity:	88/343 - (25%)
Similarity:	134/343 - (39%)	Gaps:	110/343 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 WIGLPF------WWAKSQLVTYFLLIV---GNWLLLNVVFH---------YVMAVITPAGHP--- 126
            ||.:.|      |...:.:|...||.:   |..::..||||         |...:.|...:|
Zfish    48 WIPVIFIALVVCWSYYAYVVELCLLTISSTGEKIVYLVVFHLSFVMFVWSYWKTIFTKPANPSKE 112

  Fly   127 ----------------PE---------GVSL-------VEAVSMCGKCIAPKPPRTHHCSICNRC 159
                            ||         ..||       ..|:..|.:|...||.|.||||.|:.|
Zfish   113 FCLPKSEKEQYEKEQRPETQQEILKKVATSLPLYTRTGAGAIRYCDRCQVIKPDRCHHCSACDMC 177

  Fly   160 ILKMDHHCPWLNNCVGYGNHRYFFLYMTYTTLGCLFLILFGLEIGHKYLWLDHGENWTEIEPLEG 224
            :|||||||||:|||||:.|:::|.|::||:.:.|||:....|:...|:        ||.......
Zfish   178 VLKMDHHCPWVNNCVGFSNYKFFILFLTYSLVYCLFIAASVLQYFIKF--------WTLCRRKSA 234

  Fly   225 QPVKFNLSGHIIPVTHPNEYDEFVLPPAVHNLPTPIVDTDAASPGRRRALWFMAFTNVAVVLALG 289
            :    |.....:|.:|..          .|.|                   |:.|......:::.
Zfish   235 E----NCPKSDLPESHAK----------FHVL-------------------FLFFVAAMFCISIL 266

  Fly   290 SLSIWHAKLITRGETSVEAHINEAERKRHLQQQRIYINPYNFGTKKNWKLFLGLVRG--RSFWRT 352
            ||..:|..|:.:..:::||.  .|...|:...:    |.::.|..||    :..|.|  :.:|
Zfish   267 SLFTYHLWLVGKNRSTIEAF--RAPVFRNGPDK----NGFSLGFSKN----IAQVFGDEKKYW-- 319

  Fly   353 VLLPSWHKPEGTGLSFHT 370
             |||.: ..:|.||||.|
Zfish   320 -LLPVF-TSQGDGLSFPT 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	zf-DHHC	139..>201	CDD:279823	33/61 (54%)
zdhhc20b	XP_005162815.2	zf-DHHC	44..342	CDD:327686	88/343 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55511
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.930