Protein Alignment gb and SLC7A10

DIOPT Version :10

• Sequence 1: NP_651536.1
• Gene: gb / 43265
• FlyBaseID: FBgn0039487
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: XP_011525421.1
• Gene: SLC7A10 / 56301
• HGNCID: 11058
• Length: 660
• Species: Homo sapiens
• Alignment Length: 662
• Identity: 215/662 - (32%)
• Similarity: 326/662 - (49%)
• Gaps: 169/662 - (25%)

  Fly     4 ADELQSPSSEMVLLTPSSGNPPSSIAQPAANPAEKAQCREGSAESDSSRVVIKKQLGLLEGVAII 68
            |...|.||..        |||     :||.:|:..    .|:....|.||.:||::|||....||
Human     2 AGHTQQPSGR--------GNP-----RPAPSPSPV----PGTVPGASERVALKKEIGLLSACTII 49

  Fly    69 LGIIFGSGIFVSPKGVIREVESVGASLVIWVLCGLLSMIGALCYAELGTAIPKSGGDYAYIFEAY 133
            :|.|.|||||:|||||:....|||.:|.:|||.|.::.:|:|||||||.|||||||||||:.|.:
Human    50 IGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIF 114

  Fly   134 GSLPAFLYLWDAMMIFVPTTNAIMGLTFASYVLEPFFGGACEIPKIALQLLAAITICFLTYLNSY 198
            |.|..||.||.|::|..||:.|::.:||::|||:|.|.. |..|..|.::|:...:..||::||.
Human   115 GGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPN-CIPPTTASRVLSMACLMLLTWVNSS 178

  Fly   199 YMKVTTKMQNVIMFTKIAALVLIILVGLVWMMMGNVENFTRP-----FDNTETDPGKMSVAFYSG 258
            .::..|::|::....|:.||.|||.|||:.:..|:.|.. ||     |..|.: .|.:::||..|
Human   179 SVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEEL-RPSNAFAFWMTPS-VGHLALAFLQG 241

  Fly   259 IFSYAGWNYLNFMTEELRDPYRNLPRAIYISLPLVTGIYVLANVAYLAVLSPSEMIASNAIAVTF 323
            .|:::|||:||::|||:.|..:||||||:||:||||.:|...|:||...:||.|:::|||:||..
Human   242 SFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVVS 306

  Fly   324 GDKILGVFSLIIPL---------------------------------------------MVAISA 343
            | .:||.:.|..||                                             ::.::|
Human   307 G-PLLGPWLLPRPLPRPYTWPLYCAHPDLRGEAAGLLFLGHACLRGSVNLRRDQWLPVHLLQVTA 370

  Fly   344 FG----------------------------------------GLSVHIMT--------------- 353
            .|                                        |....|.|
Human   371 LGRRGHGEGRLGCRCAPVMPWARGRDTCRGRGLPEAGMMIPHGNKCLITTGRQRKQEAGRLDEGE 435

  Fly   354 --------------------------------------SSRICFVGARNGHMPAILSHISVKSYT 380
                                                  ::|:||.|||.||:|::|:.|.|:..|
Human   436 NCPVGLLGPEQEVRGDSLRGTSGPKLRPRMWPVPISVPNARLCFSGAREGHLPSLLAMIHVRHCT 500

  Fly   381 PLPSLVFLCFLSIVMLVVSDVYVLITYASIVESFFIMLSVSAVLYFRYTRPCMERPIKVAMWIPA 445
            |:|:|:..|..:.|:::|.|.|.||.|.|.:......:::..:|..|:.||.:.|||||.:.||.
Human   501 PIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPV 565

  Fly   446 LFVIVCAFLVVVPIYVAPYEVGMGVLITIIGIPFYYVGVVWKNKPKWVQSTIDSVTFTCQKLF-- 508
            .:::..|||:|......|...|:||:|.:.|:|.:::||.|::|||.|....:|:|...|:|.
Human   566 AYLVFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFV 630

  Fly   509 ---MSAKEEKED 517
               ..|.||:|:
Human   631 VYPQDAPEEEEN 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gb	NP_651536.1	2A0308	32..515	CDD:273332	205/630 (33%)
SLC7A10	XP_011525421.1	2A0308	15..635	CDD:273332	204/627 (33%)