Protein Alignment gb and Slc7a12

DIOPT Version :10

• Sequence 1: NP_651536.1
• Gene: gb / 43265
• FlyBaseID: FBgn0039487
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001011948.1
• Gene: Slc7a12 / 294881
• RGDID: 1309208
• Length: 472
• Species: Rattus norvegicus
• Alignment Length: 478
• Identity: 138/478 - (28%)
• Similarity: 246/478 - (51%)
• Gaps: 41/478 - (8%)

  Fly    59 LGLLEGVAIILGIIFGSGIFVSPKGVIREVE-SVGASLVIWVLCGLLSMIGALCYAELGTAIPKS 122
            ||.......:.....|:|||||||||::... ::...|.||..||||||:.|:|.||:....|.|
  Rat     7 LGFFHVNMFLFSATIGTGIFVSPKGVLKYCSLNIPIFLSIWAGCGLLSMMNAVCLAEIAATYPVS 71

  Fly   123 GGDYAYIFEAYGSLPAFLYLWDAMMIFVPTTN-AIMGLTFASYVLEPFFGGACEIPKIALQLLAA 186
            |..|.::..|.||..|||.:|  :.||..|.. :...|..||.:::.|: ..|:.|::..:.||.
  Rat    72 GASYYFLKRALGSSVAFLSIW--IKIFACTLGISAQCLLIASSLIQCFY-SECQAPELPKKCLAL 133

  Fly   187 ITICFLTYLNSYYMKVTTKMQNVIMFTKIAALVLIILVGLVWMMMG---NVENFTRPFDNTETDP 248
            ..:.....|::..:|.......:....|::.|.||.|.|:|.:::|   ||..|.:..:....:.
  Rat   134 AILWSFGILSARGIKPVAWFNTISSLMKLSVLCLISLTGIVLLVIGKKENVSRFEKALEAELPNV 198

  Fly   249 GKMSVAFYSGIFSYAGWNYLNFMTEELRDPYRNLPRAIYISLPLVTGIYVLANVAYLAVLSPSEM 313
            .:::.|.....::|.|.::|..:..|::.|...:|::|...|.:||.:|:|.||::||||:..|:
  Rat   199 SQIAEAILQVYYAYLGSSFLIVIAGEIKRPAETIPKSIIYGLSVVTVLYLLTNVSFLAVLTSEEI 263

  Fly   314 IASNAIAVTFGDKILGVFSLIIPLMVAISAFGGLSVHIMTSSRICFVGARNGHMPAILSHISVKS 378
            |:|:::|||:.:::......||.|:::...||.:|..|:::|||.:..::.|..|.|.|.:: ..
  Rat   264 ISSDSVAVTWMNRVFPSMQWIISLLISAFLFGSVSCGIVSASRIFYATSQEGQFPFIYSMLN-DL 327

  Fly   379 YTPLPSLVFLCFLSIVMLVVSDVYVLITYASIVESFFIMLSVSAVLYFRYTRPCMERPIKVAMWI 443
            ::|:.:.:....||.|.::.|::..||.|..:......:|::..:|..||..|.:.||.||.  :
  Rat   328 HSPVVADLQAVILSSVGIISSNMIYLIKYVGLGTWCLNLLNMIGLLKLRYQNPDLPRPYKVR--L 390

  Fly   444 PALFVIVCA--FLVVVPIYVAP-----YEVGMGVLITIIGIPFYYVGVVWKNKPKWVQSTID--S 499
            |.:|..:.:  ||::.|:..:|     |:|           .|.:.|::.    .|:|:.::  .
  Rat   391 PFVFGSIASSLFLILTPVIQSPSTEHVYQV-----------VFLFCGLLC----YWLQAYLNRHG 440

  Fly   500 VTF---TC--QKLF-MSAKEEKE 516
            |.|   ||  |.|| :|..|..|
  Rat   441 VCFNRITCYWQLLFNVSPSEHPE 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gb	NP_651536.1	2A0308	32..515	CDD:273332	137/475 (29%)
Slc7a12	NP_001011948.1	2A0308	21..423	CDD:273332	122/418 (29%)