Protein Alignment gb and SLC7A8

DIOPT Version :10

• Sequence 1: NP_651536.1
• Gene: gb / 43265
• FlyBaseID: FBgn0039487
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_036376.2
• Gene: SLC7A8 / 23428
• HGNCID: 11066
• Length: 535
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 221/500 - (44%)
• Similarity: 331/500 - (66%)
• Gaps: 26/500 - (5%)

  Fly    34 NPAEKAQCREGSAESDSS--------RVVIKKQLGLLEGVAIILGIIFGSGIFVSPKGVIREVES 90
            |..||.  ..|..|||:|        .|.:||::||:....||:|.|.|||||||||||:....|
Human     9 NNTEKK--HPGGGESDASPEAGSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGS 71

  Fly    91 VGASLVIWVLCGLLSMIGALCYAELGTAIPKSGGDYAYIFEAYGSLPAFLYLWDAMMIFVPTTNA 155
            ||.:|::|::.|.::::|||||||||..||||||||:|:.:.:|.|..||.||.|:::..||..|
Human    72 VGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQA 136

  Fly   156 IMGLTFASYVLEPFFGGACEIPKIALQLLAAITICFLTYLNSYYMKVTTKMQNVIMFTKIAALVL 220
            ::.|||::|||:|.| ..|..|:..|:|||||.:..||::|...::..|::|::....|:.||.|
Human   137 VIALTFSNYVLQPLF-PTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALAL 200

  Fly   221 IILVGLV--------WMMMGNV-ENFTRPFDNTETDPGKMSVAFYSGIFSYAGWNYLNFMTEELR 276
            ||::|:|        |:...|. |||..|      |.|.:::||..|.|:|.|||:||::||||.
Human   201 IIIMGIVQICKGEYFWLEPKNAFENFQEP------DIGLVALAFLQGSFAYGGWNFLNYVTEELV 259

  Fly   277 DPYRNLPRAIYISLPLVTGIYVLANVAYLAVLSPSEMIASNAIAVTFGDKILGVFSLIIPLMVAI 341
            |||:||||||:||:||||.:||.|||||:..:||.|::||||:|||||:|:|||.:.|:|:.||:
Human   260 DPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVAL 324

  Fly   342 SAFGGLSVHIMTSSRICFVGARNGHMPAILSHISVKSYTPLPSLVFLCFLSIVMLVVSDVYVLIT 406
            |.|||::..:.||||:.|.|||.||:|::|:.|.||..||:|:|:|.|..:::|||.||:|.||.
Human   325 STFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLIN 389

  Fly   407 YASIVESFFIMLSVSAVLYFRYTRPCMERPIKVAMWIPALFVIVCAFLVVVPIYVAPYEVGMGVL 471
            |...:...|..::|:..:..|:.:|.:.||||:.:..|.::::..|||:|..::..|...|:|:.
Human   390 YVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGLA 454

  Fly   472 ITIIGIPFYYVGVVWKNKPKWVQSTIDSVTFTCQKLFMSAKEEKE 516
            |.:.|:|.|::||.|::|||.....|:.:|...||:.:....|.|
Human   455 IMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVE 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gb	NP_651536.1	2A0308	32..515	CDD:273332	219/497 (44%)
SLC7A8	NP_036376.2	2A0308	1..497	CDD:273332	219/496 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		8/22 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	502..535