DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH9 and ACA5

DIOPT Version :9

Sequence 1:	NP_651535.1	Gene:	CAH9 / 43264	FlyBaseID:	FBgn0039486	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_172285.2	Gene:	ACA5 / 837324	AraportID:	AT1G08065	Length:	277	Species:	Arabidopsis thaliana

Alignment Length:	317	Identity:	86/317 - (27%)
Similarity:	130/317 - (41%)	Gaps:	72/317 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLTAFLEASFLLICWSQAVSSH----------VFGYSEPNQR---RWARHHGHCA----GKTQS 48
            ||:.:.....||:......|||.          .|.|.:..::   .|.|.....|    |..||
plant     1 MKIPSIGYVFFLIFISITIVSSSPDHGEVEDETQFNYEKKGEKGPENWGRLKPEWAMCGKGNMQS 65

  Fly    49 PIAITTSRTTAIHMPAVDMIGY--HNLLPYPLKMINNGHTVSITIPKVNVTEVGEDFLPYIRGAK 111
            ||.:|..|....|     .:||  ...||....:.|.||.:.:..      |.|...|    |..
plant    66 PIDLTDKRVLIDH-----NLGYLRSQYLPSNATIKNRGHDIMMKF------EGGNAGL----GIT 115

  Fly   112 LPG-EFEVEGLHFHWGDKNNRGSEHVINDIRYTMEMHIVHRNKKYATIGEALNHPDGA-AVLGFF 174
            :.| |::::.:|:|      ..|||.:|..|:.:|.|:||::|            ||. ||:.||
plant   116 INGTEYKLQQIHWH------SPSEHTLNGKRFVLEEHMVHQSK------------DGRNAVVAFF 162

  Fly   175 FNLDEDEGAGLVTINRHLHLIADANQ-----EATLNVTFSLSSLIAGVDVDKFYTYKGSLTTPPC 234
            :.|.:.: ..|:|:.|:|..|.|.::     |.....||       |.:...:|.:.||||||||
plant   163 YKLGKPD-YFLLTLERYLKRITDTHESQEFVEMVHPRTF-------GFESKHYYRFIGSLTTPPC 219

  Fly   235 SEAVTWILFPDPIPISPKQISRFRQLSDTQDGALVDNFRTLQPVGNR--RIFARTGH 289
            ||.|.|.:..:...::.||:...|.....|..:   |.|.||....|  .::..|.|
plant   220 SENVIWTISKEMRTVTLKQLIMLRVTVHDQSNS---NARPLQRKNERPVALYIPTWH 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH9	NP_651535.1	Carb_anhydrase	25..282	CDD:215000	77/274 (28%)
ACA5	NP_172285.2	PLN02179	9..231	CDD:177835	73/262 (28%)
ACA5	NP_172285.2	alpha_CA_prokaryotic_like	44..265	CDD:239398	75/264 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2610
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I2251
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	1	1.000	-	-		mtm1014
orthoMCL	1	0.900	-	-		OOG6_100138
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.770