Protein Alignment CAH9 and CA6

DIOPT Version :10

• Sequence 1: NP_651535.1
• Gene: CAH9 / 43264
• FlyBaseID: FBgn0039486
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: XP_011540386.1
• Gene: CA6 / 765
• HGNCID: 1380
• Length: 324
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 99/318 - (31%)
• Similarity: 151/318 - (47%)
• Gaps: 41/318 - (12%)

  Fly     1 MKLTAFLEASFLLICWSQAVSSHVFGYSEPNQRRWARHHGHCAGKTQSPIAITTSRTTAIHMPA- 64
            |:....|.:.|||...:|.||...:.....::..|.:|:..|.|:.||||.:  .||...:.|:
Human     5 MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINL--QRTKVRYNPSL 67

  Fly    65 --VDMIGYHNLL-PYPLKMINNGHTVSITIPKVNVTEVGEDFLPYIRGAKLPGEFEVEGLHFHWG 126
              ::|.||.... .:|  |:||||||.|::|......|. |...||          .:.:|||||
Human    68 KGLNMTGYETQAGEFP--MVNNGHTVQISLPSTMRMTVA-DGTVYI----------AQQMHFHWG 119

  Fly   127 DKNNR--GSEHVINDIRYTMEMHIVHRNKKYATIGEALNHPDGAAVLGFFFNL-DEDEGAGLVTI 188
            ..::.  ||||.::.||:.:|:||||.|.||.:...|.:.|||.|||..|..: :..|.......
Human   120 GASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNF 184

  Fly   189 NRHLHLIADANQEATLNVTFSLSSLIAGVDV--------DKFYTYKGSLTTPPCSEAVTWILFPD 245
            ..||..|....|..||          .|:||        ..:|||.||||||||:|.|.|.:..|
Human   185 ISHLANIKYPGQRTTL----------TGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLAD 239

  Fly   246 PIPISPKQISRF-RQLSDTQDGALVDNFRTLQPVGNRRIFARTGHVRHTSIATLKHEG 302
            .:.:|..|:.:. ..|.|.::..:.:::|..||:.:|.:.:...:..:..|.:.|..|
Human   240 FVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQENAYIPSGKGHG 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH9	NP_651535.1	Carb_anhydrase	31..286	CDD:459707	88/270 (33%)
CA6	XP_011540386.1	alpha_CA_VI	35..283	CDD:239399	88/272 (32%)