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Protein Alignment CAH9 and CA2

DIOPT Version :9

Sequence 1:	NP_651535.1	Gene:	CAH9 / 43264	FlyBaseID:	FBgn0039486	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_000058.1	Gene:	CA2 / 760	HGNCID:	1373	Length:	260	Species:	Homo sapiens

Alignment Length:	269	Identity:	90/269 - (33%)
Similarity:	137/269 - (50%)	Gaps:	18/269 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 SHVFGYSEPN-QRRWARHHGHCAGKTQSPIAITTSRTTAIHMPAVDMIGYHNLLPYPLKMINNGH 85
            ||.:||.:.| ...|.:......|:.|||:.|.|.  ||.:.|::..:.........|:::||||
Human     2 SHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTH--TAKYDPSLKPLSVSYDQATSLRILNNGH 64

  Fly    86 TVSITIPKVNVTEVGEDFLPYIRGAKLPGEFEVEGLHFHWGDKNNRGSEHVINDIRYTMEMHIVH 150
            ..::.........|       ::|..|.|.:.:...|||||..:.:||||.::..:|..|:|:||
Human    65 AFNVEFDDSQDKAV-------LKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVH 122

  Fly   151 RNKKYATIGEALNHPDGAAVLGFFFNLDEDEGAGLVTINRHLHLIADANQEATLNVTFSLSSLIA 215
            .|.||...|:|:..|||.||||.|..:...: .||..:...|..|....:.|..........|..
Human   123 WNTKYGDFGKAVQQPDGLAVLGIFLKVGSAK-PGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPE 186

  Fly   216 GVDVDKFYTYKGSLTTPPCSEAVTWILFPDPIPISPKQISRFRQLSDTQDG----ALVDNFRTLQ 276
            .:|   ::||.|||||||..|.||||:..:||.:|.:|:.:||:|:...:|    .:|||:|..|
Human   187 SLD---YWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQ 248

  Fly   277 PVGNRRIFA 285
            |:.||:|.|
Human   249 PLKNRQIKA 257

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.