Protein Alignment CAH9 and CA1

DIOPT Version :10

• Sequence 1: NP_651535.1
• Gene: CAH9 / 43264
• FlyBaseID: FBgn0039486
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_001729.1
• Gene: CA1 / 759
• HGNCID: 1368
• Length: 261
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 82/279 - (29%)
• Similarity: 132/279 - (47%)
• Gaps: 33/279 - (11%)

  Fly    20 VSSHVFGYSEPN-QRRWARHHGHCAGKTQSPIAITTSRTTAIHMPAVDMIGYHNLLPYPLKMINN 83
            ::|..:||.:.| ..:|::.:....|..|||:.|.||.|.  |..::..|..........::||.
Human     1 MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETK--HDTSLKPISVSYNPATAKEIINV 63

  Fly    84 GHTVSITIPKVNVTEVGEDFLPYIRGAKLPGEFEVEGLHFHWGDKNNRGSEHVINDIRYTMEMHI 148
            ||:..:...       ..|....::|......:.:...|||||..|..||||.::.::|:.|:|:
Human    64 GHSFHVNFE-------DNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHV 121

  Fly   149 VHRNK-KYATIGEALNHPDGAAVLGFFFNLDEDEGAGLVTINRHLHLIADANQEATLN------V 206
            .|.|. ||:::.||.:..||.||:|....:.|        .|..|..:.||.|.....      .
Human   122 AHWNSAKYSSLAEAASKADGLAVIGVLMKVGE--------ANPKLQKVLDALQAIKTKGKRAPFT 178

  Fly   207 TFSLSSLI-AGVDVDKFYTYKGSLTTPPCSEAVTWILFPDPIPISPKQISRFRQLSDTQDG---- 266
            .|..|:|: :.:|   |:||.||||.||..|:||||:..:.|.:|.:|:::||.|....:|
Human   179 NFDPSTLLPSSLD---FWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240

  Fly   267 ALVDNFRTLQPVGNRRIFA 285
            .:..|.|..||:..|.:.|
Human   241 PMQHNNRPTQPLKGRTVRA 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH9	NP_651535.1	Carb_anhydrase	31..286	CDD:459707	79/268 (29%)
CA1	NP_001729.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		7/29 (24%)
		alpha_CA	2..261	CDD:469577	82/278 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	241..261		6/19 (32%)