DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH9 and ca16b

DIOPT Version :9

Sequence 1:	NP_651535.1	Gene:	CAH9 / 43264	FlyBaseID:	FBgn0039486	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	XP_001919055.3	Gene:	ca16b / 569183	ZFINID:	ZDB-GENE-080818-1	Length:	1382	Species:	Danio rerio

Alignment Length:	314	Identity:	93/314 - (29%)
Similarity:	137/314 - (43%)	Gaps:	51/314 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LEASFLLICWSQAVSSHVFGY-------SEPNQ-------------------RRWARHHGHCAGK 45
            |..|.|||   |.:|.|...:       |..||                   ||||..:..|..:
Zfish    15 LTLSALLI---QPISCHPASHVETVRRGSSANQRERRASGEPYWAYSGTYGPRRWASAYPECGER 76

  Fly    46 TQSPIAITTSRT-TAIHMPAVDMIGYHNLLPYPLKMINNGHTVSITIPKVNVTEVGEDFLPYIRG 109
            .|||:.|....| .:.....:.:.|:.........|.|.|.||||.:.        .|:  ::||
Zfish    77 NQSPVDILDPETQVSQECQELTLDGFETKSSNRTTMKNTGKTVSIVLK--------NDY--FVRG 131

  Fly   110 AKLPGEFEVEGLHFHWGDKN-NRGSEHVINDIRYTMEMHIVHRNK-KYATIGEALNHPDGAAVLG 172
            |.|||.|:.|.:.||||..| :.||||.||..::.:||.|...|. .:.::..|:......|.:.
Zfish   132 AGLPGRFKAEKVEFHWGSTNGSAGSEHSINGKKFPVEMQIYFYNSDDFDSLSTAIKERRIIAAMA 196

  Fly   173 FFFNLDEDEGAGLVTINRHLHLIADANQEATLNVTFSLSSLIAGVDVDKFYTYKGSLTTPPCSEA 237
            .||.:...:......|...|..:....:|..|. :|.|..|:.. .:..:|.|.|||||||||:.
Zfish   197 VFFQVATKDNIAAEPIIAGLKRVVHHEKETNLG-SFILRDLLPS-SLGSYYRYTGSLTTPPCSKV 259

  Fly   238 VTWILFPDPIPISPKQISRFRQL--SDTQDGA-----LVDNFRTLQPVGNRRIF 284
            |.||:|..|:.:|..|:..|..:  ::.||..     |.:|.|.:|.:.:||||
Zfish   260 VEWIIFSRPVYLSYHQLEAFYSIFTTEQQDHVKSVDYLRNNHRPIQDLDSRRIF 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH9	NP_651535.1	Carb_anhydrase	25..282	CDD:215000	81/292 (28%)
ca16b	XP_001919055.3	alpha_CARP_receptor_like	62..314	CDD:239396	82/264 (31%)
		FN3	340..417	CDD:214495
		Herpes_BLLF1	450..>557	CDD:330317
		PTPc	790..1057	CDD:214550
		PTPc	1089..1347	CDD:214550
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810