DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH9 and ca8

DIOPT Version :9

Sequence 1:	NP_651535.1	Gene:	CAH9 / 43264	FlyBaseID:	FBgn0039486	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001011213.1	Gene:	ca8 / 496646	XenbaseID:	XB-GENE-953676	Length:	282	Species:	Xenopus tropicalis

Alignment Length:	278	Identity:	92/278 - (33%)
Similarity:	141/278 - (50%)	Gaps:	36/278 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 FGYSEPNQRRWARHHGHCAGKTQSPIAITTSRTTAIHMPAVDMIGYHNLLP-YPL----KMINNG 84
            :||.|..:  |...:....|..||||.|.:..  |::.|::..:   .|.| |.:    ::||:|
Frog    21 WGYEEGVE--WGLLYPEANGDYQSPININSRE--AMYDPSLLEV---RLTPSYVVCRDCEVINDG 78

  Fly    85 HTVSITIPKVNVTEVGEDFLPYIRGAKLP--GEFEVEGLHFHWGDKNNRGSEHVINDIRYTMEMH 147
            |.|.|.:...:|          ::|..||  .|:|:..:.||||.:|.|||||.:|...:.||:|
Frog    79 HVVQILLKSKSV----------LKGGPLPRGHEYELNEVRFHWGKENQRGSEHTVNFKAFPMELH 133

  Fly   148 IVHRNKK-YATIGEALNHPDGAAVLGFFFNLDEDEGAGLVTINRHLHLIADANQEATLNVTFSLS 211
            ::|.|.. |.::.||:....|..::..|..:.: |..||..|...|..|....:..|: ..|:.:
Frog   134 LIHWNSTLYRSLEEAMGKVHGIVIISLFVQIGK-ENIGLKAITEVLQDIFYKGKSKTI-PCFNPN 196

  Fly   212 SLIAGVDVDKFYTYKGSLTTPPCSEAVTWILFPDPIPISPKQISRFRQ---------LSDTQDGA 267
            :|:....:..::.|:||||.|||||.||||||..|:.:|..||..||:         |.|..||.
Frog   197 TLLPDPLLRDYWVYEGSLTMPPCSEGVTWILFRYPLTVSQTQIEEFRRLRTHIKGADLPDGCDGL 261

  Fly   268 LVDNFRTLQPVGNRRIFA 285
            :.||||..||:.:|.|.|
Frog   262 MADNFRPTQPLSDRIIRA 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH9	NP_651535.1	Carb_anhydrase	25..282	CDD:215000	89/273 (33%)
ca8	NP_001011213.1	alpha_CARP_VIII	26..281	CDD:239394	89/273 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920