back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CAH9 and CA13

DIOPT Version :9

Sequence 1:	NP_651535.1	Gene:	CAH9 / 43264	FlyBaseID:	FBgn0039486	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_940986.1	Gene:	CA13 / 377677	HGNCID:	14914	Length:	262	Species:	Homo sapiens

Alignment Length:	283	Identity:	93/283 - (32%)
Similarity:	130/283 - (45%)	Gaps:	51/283 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 FGYSEPN-QRRWARHHGHCAGKTQSPIAITTSRTTAIHMPAVDMIGYHNLL--------PYPLKM 80
            :||.|.| ...|........|..||||.|.|..           :.|.:.|        |...|:
Human     6 WGYREHNGPIHWKEFFPIADGDQQSPIEIKTKE-----------VKYDSSLRPLSIKYDPSSAKI 59

  Fly    81 I-NNGHTVSITIPKVNVTEVGEDFLPYIRGAKLPGEFEVEGLHFHWGDKNNRGSEHVINDIRYTM 144
            | |:||:.::.........|       :||..|.|.:.:..:|.|||..::.||||:::.:.|..
Human    60 ISNSGHSFNVDFDDTENKSV-------LRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAA 117

  Fly   145 EMHIVHRNK-KYATIGEALNHPDGAAVLGFFFNLDEDEGAGLVTINRHLHLIADA------NQEA 202
            |:|:||.|. ||.:..||.:.|||.||||.|..:.|.        |..|..|.|.      ..:.
Human   118 ELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEP--------NSQLQKITDTLDSIKEKGKQ 174

  Fly   203 TLNVTFSLSSLI-AGVDVDKFYTYKGSLTTPPCSEAVTWILFPDPIPISPKQISRFRQLSDTQDG 266
            |....|.|.||: ...|   ::||.||||.||..|:||||:...||.||.:|:::||.|..|.:|
Human   175 TRFTNFDLLSLLPPSWD---YWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEG 236

  Fly   267 A----LVDNFRTLQPVGNRRIFA 285
            .    ||.|.|..||:..|::.|
Human   237 EAAAFLVSNHRPPQPLKGRKVRA 259

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.