DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH9 and Ca6

DIOPT Version :9

Sequence 1:	NP_651535.1	Gene:	CAH9 / 43264	FlyBaseID:	FBgn0039486	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001128313.1	Gene:	Ca6 / 298657	RGDID:	70516	Length:	312	Species:	Rattus norvegicus

Alignment Length:	297	Identity:	95/297 - (31%)
Similarity:	146/297 - (49%)	Gaps:	39/297 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LTAFLEASFLLICWSQAVSSHVFGYSEPN---QRRWARHHGHCAGKTQSPIAIT------TSRTT 58
            |.:.:...||.|   ||:|.  :.||..:   :.||...:..|.|:.||||.:.      :|...
  Rat     4 LVSVVSLFFLGI---QALSE--WSYSGDDGLEESRWPEKYPSCGGERQSPIDVKRREVHFSSSLL 63

  Fly    59 AIHMPAVDMIGYHNLLPYPLKMINNGHTVSITIPKVNVTEVGEDFLPYIRGAKLPGEFEVEGLHF 123
            .:||...:..|..      |.|.||||||.||:|........:..:           :..:.:||
  Rat    64 PLHMVNYEEEGLE------LSMTNNGHTVQITLPNTMSMRDSDGTV-----------YRTKQMHF 111

  Fly   124 HWGDKNNR--GSEHVINDIRYTMEMHIVHRNKKYATIGEALNHPDGAAVLGFFFNL-DEDEGAGL 185
            |||.:::.  ||||.|:.:|:.:|:|:||.|:||.|..:|::.|||.||:.....: |..|....
  Rat   112 HWGGRDSEISGSEHTIDGMRHAIEIHLVHFNEKYETYEKAVDQPDGLAVMAVLVKVEDYTENDYY 176

  Fly   186 VTINRHLHLIADANQEATL-NVTFSLSSLIAGVDVDKFYTYKGSLTTPPCSEAVTWILFPDPIPI 249
            .|....|..:....|..|| ||  ::.:::.| |:..:|||:||||||||:|.|.|.:|.|...|
  Rat   177 STFISELENVKYTGQTTTLRNV--NIRNMLPG-DIRHYYTYQGSLTTPPCTENVKWFVFQDSATI 238

  Fly   250 SPKQISRFRQ-LSDTQDGALVDNFRTLQPVGNRRIFA 285
            |..|..|... :.|..:..:.:.:|..||:.||.:.|
  Rat   239 SKAQAERIENAVMDHHNQTIRNGYRRTQPLHNRVVEA 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH9	NP_651535.1	Carb_anhydrase	25..282	CDD:215000	86/270 (32%)
Ca6	NP_001128313.1	alpha_CA_VI	30..278	CDD:239399	86/266 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339389
Domainoid	1	1.000	146	1.000	Domainoid score	I4412
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	146	1.000	Inparanoid score	I4322
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	1	1.000	-	-		otm44493
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.800