DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH9 and Ptprg

DIOPT Version :9

Sequence 1:	NP_651535.1	Gene:	CAH9 / 43264	FlyBaseID:	FBgn0039486	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_599183.2	Gene:	Ptprg / 171357	RGDID:	620774	Length:	1442	Species:	Rattus norvegicus

Alignment Length:	257	Identity:	80/257 - (31%)
Similarity:	118/257 - (45%)	Gaps:	22/257 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 WARHHGHCAGKTQSPIAITTSRT-TAIHMPAVDMIGYHNLLPYPLKMINNGHTVSITIPKVNVTE 98
            |......|.|..||||.|..... .......:.:.|:.|.......|.|.|.||:|.:.
  Rat    71 WVTSSVSCGGSHQSPIDILDHHARVGEEYQELQLDGFDNESSNKTWMKNTGKTVAILLK------ 129

  Fly    99 VGEDFLPYIRGAKLPGEFEVEGLHFHWGDKN-NRGSEHVINDIRYTMEMHIVHRN-KKYATIGEA 161
              :|:  ::.||.|||.|:.|.:.||||..| :.||||.:|..|:.:||.|...| ..:.:...|
  Rat   130 --DDY--FVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTA 190

  Fly   162 LNHPDGAAVLGFFFNLDEDEGAGLVTINRHLHLIADANQEATLNVTFSLSSLIAGVDVDKFYTYK 226
            ::.......:..||.:...:.:.|..|...|..:....:|..|: .|.|..|:. ..:..:|.|.
  Rat   191 ISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLD-PFVLRDLLP-ASLGSYYRYT 253

  Fly   227 GSLTTPPCSEAVTWILFPDPIPISPKQISRFRQL--SDTQDGA-----LVDNFRTLQPVGNR 281
            ||||||||||.|.||:|..|:|||..|:..|..:  ::.||..     |.:|||..|.:.:|
  Rat   254 GSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQALNDR 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH9	NP_651535.1	Carb_anhydrase	25..282	CDD:215000	80/257 (31%)
Ptprg	NP_599183.2	alpha_CARP_receptor_like	67..319	CDD:239396	80/257 (31%)
		FN3	348..438	CDD:238020
		R-PTPc-G-1	845..1118	CDD:350505
		R-PTP-G-2	1202..1406	CDD:350508
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810