DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH9 and Car8

DIOPT Version :9

Sequence 1:	NP_651535.1	Gene:	CAH9 / 43264	FlyBaseID:	FBgn0039486	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_031618.2	Gene:	Car8 / 12319	MGIID:	88253	Length:	291	Species:	Mus musculus

Alignment Length:	274	Identity:	90/274 - (32%)
Similarity:	139/274 - (50%)	Gaps:	28/274 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 FGYSEPNQRRWARHHGHCAGKTQSPIAITTSRTTAIHMPAVDM-IGYHNLLPYPLKMINNGHTVS 88
            :||.|..:  |........|:.||||.: .||........:|: :..:.::....::.|:|||:.
Mouse    30 WGYEEGVE--WGLVFPDANGEYQSPINL-NSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQ 91

  Fly    89 ITIPKVNVTEVGEDFLPYIRGAKLP--GEFEVEGLHFHWGDKNNRGSEHVINDIRYTMEMHIVHR 151
            :.:...:|          :.|..||  .|||:..:.||||.:|.|||||.:|...:.||:|::|.
Mouse    92 VILKSKSV----------LSGGPLPQGQEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHW 146

  Fly   152 NKK-YATIGEALNHPDGAAVLGFFFNLDEDEGAGLVTINRHLHLIADANQEATLNVTFSLSSLIA 215
            |.. :.:|.||:..|.|.|::..|..:.: |..||..:...|..|....:..|: ..|:.::|:.
Mouse   147 NSTLFGSIDEAVGKPHGIAIIALFVQIGK-EHVGLKAVTEILQDIQYKGKSKTI-PCFNPNTLLP 209

  Fly   216 GVDVDKFYTYKGSLTTPPCSEAVTWILFPDPIPISPKQISRFR---------QLSDTQDGALVDN 271
            ...:..::.|:||||.|||||.||||||..|:.||..||..||         :|.:..||.|.||
Mouse   210 DPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQMQIEEFRRLRTHVKGAELVEGCDGILGDN 274

  Fly   272 FRTLQPVGNRRIFA 285
            ||..||:.:|.|.|
Mouse   275 FRPTQPLSDRVIRA 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH9	NP_651535.1	Carb_anhydrase	25..282	CDD:215000	87/269 (32%)
Car8	NP_031618.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28
Car8	NP_031618.2	alpha_CARP_VIII	36..290	CDD:239394	87/268 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835763
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750