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Protein Alignment CAH9 and CA5B

DIOPT Version :9

Sequence 1:	NP_651535.1	Gene:	CAH9 / 43264	FlyBaseID:	FBgn0039486	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_009151.1	Gene:	CA5B / 11238	HGNCID:	1378	Length:	317	Species:	Homo sapiens

Alignment Length:	261	Identity:	76/261 - (29%)
Similarity:	124/261 - (47%)	Gaps:	38/261 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 GKTQSPIAITTSRTTAIHMPAVDMIGYHNLLPYP----LKMINNGHTVSITIPKVNVTEVGEDFL 104
            |..||||.|..  ..:::.|.:..:    .:.|.    |.:.|||::..:.........|
Human    61 GDRQSPINIRW--RDSVYDPGLKPL----TISYDPATCLHVWNNGYSFLVEFEDSTDKSV----- 114

  Fly   105 PYIRGAKLPGEFEVEGLHFHWGDKNNRGSEHVINDIRYTMEMHIVHRNK-KYATIGEALNHPDGA 168
              |:|..|...:.::..|||||..:..||||.::...:..|:|:||.|. ::....:|....:|.
Human   115 --IKGGPLEHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEENGL 177

  Fly   169 AVLGFFFNLDEDEGAGLVTINRHLHLIADA-----NQEATLNV-TFSLSSLIAGVDVDKFYTYKG 227
            ||:|.|..|.:.        ::.|..:.|.     :::|.:.. :|..|.|:.  ....::||.|
Human   178 AVIGVFLKLGKH--------HKELQKLVDTLPSIKHKDALVEFGSFDPSCLMP--TCPDYWTYSG 232

  Fly   228 SLTTPPCSEAVTWILFPDPIPISPKQISRFRQLSDTQDG----ALVDNFRTLQPVGNRRIFARTG 288
            ||||||.||:||||:...|:.:...|:.:||.|..|.:|    .:|||||.|||:.||.:.:...
Human   233 SLTTPPLSESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTVRSSFR 297

  Fly   289 H 289
            |
Human   298 H 298

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.