DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH9 and ca6

DIOPT Version :9

Sequence 1:	NP_651535.1	Gene:	CAH9 / 43264	FlyBaseID:	FBgn0039486	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	XP_009295179.1	Gene:	ca6 / 100006448	ZFINID:	ZDB-GENE-030131-7091	Length:	538	Species:	Danio rerio

Alignment Length:	280	Identity:	95/280 - (33%)
Similarity:	144/280 - (51%)	Gaps:	27/280 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SQAVSSHVFGYS-EPNQRRWARHHGHCAGKTQSPIAITTSRTT-AIHMPAVDMIGYHNLLPYPLK 79
            |..|....:.|| |.:|:.||..:..|.|:.||||.|...:.. :..|..:::.||.::....|
Zfish    18 SAGVDGDYWTYSGELDQKHWAEKYHDCGGQQQSPIDIQRRKVRYSPRMQQLELTGYEDIRGSFL- 81

  Fly    80 MINNGHTVSITIPKVNVTEVGEDFLPYIRGAKLPGEFEVEGLHFHWG--DKNNRGSEHVINDIRY 142
            |.||||:|.|.:|  :..::.:.|         |.::....:|.|||  |....||||.::.|||
Zfish    82 MKNNGHSVEIQLP--STMKITKGF---------PHQYTAVQMHLHWGGWDLEASGSEHTMDGIRY 135

  Fly   143 TMEMHIVHRN-KKYATIGEALNHPDGAAVLGFFF---NLDEDEGAGLVTINRHLHLIADANQEAT 203
            ..|:|:||.| :||.:..||.|.|||.|||.|||   :.:....:..::...::..:..:...:.
Zfish   136 MAELHVVHYNSEKYPSFEEAKNKPDGLAVLAFFFEDGHFENTYYSDFISNLANIKYVGQSMSISN 200

  Fly   204 LNVTFSLSSLIAGVDVDKFYTYKGSLTTPPCSEAVTWILFPDPIPISPKQISRFRQ-LSDTQDGA 267
            |||...||.     ::..||.||||||||||.|:|.|.:|..||.:|..||.:... |.|..:..
Zfish   201 LNVLSMLSE-----NLSHFYRYKGSLTTPPCFESVMWTVFDTPITLSHNQIRKLESTLMDHDNKT 260

  Fly   268 LVDNFRTLQPVGNRRIFART 287
            |.:::|..||: |.|:...|
Zfish   261 LWNDYRMAQPL-NERVVEST 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH9	NP_651535.1	Carb_anhydrase	25..282	CDD:215000	91/265 (34%)
ca6	XP_009295179.1	alpha_CA	33..281	CDD:320708	90/265 (34%)
ca6	XP_009295179.1	LamG	332..521	CDD:328935
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579099
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.750