Protein Alignment eater and megf10

DIOPT Version :10

• Sequence 1: NP_651533.3
• Gene: eater / 43262
• FlyBaseID: FBgn0243514
• Length: 1074
• Species: Drosophila melanogaster
• Sequence 2: NP_001072726.1
• Gene: megf10 / 780183
• XenbaseID: XB-GENE-491974
• Length: 1114
• Species: Xenopus tropicalis
• Alignment Length: 1115
• Identity: 276/1115 - (24%)
• Similarity: 378/1115 - (33%)
• Gaps: 407/1115 - (36%)

  Fly    71 PNVCTCKKGY-VNLNNDPSN-----------------RC----VPYCKGCSRG---TCQSPGRCI 110
            ||||:..:.| |.:....|:                 :|    :.|.....||   ..:...:|
 Frog    30 PNVCSHWESYSVTVQESYSHPYDQVYYTSCTDILNWFKCTRHRISYRTAYRRGEKTMYRRKSQC- 93

  Fly   111 CSARHLLDKTTNNCIPQCASGCPNGTCITPNNCSCNKGYKLNPTTQVC-----LPTCKDNCAAVN 170
            |...:   ::...|:|.||..|.:|.||.||.|.|..|:.....:..|     .|.|...|...|
 Frog    94 CPGFY---ESREMCVPHCADKCVHGRCIAPNTCQCEPGWGGPNCSSACDVDHWGPHCSSRCQCKN 155

  Fly   171 GFCAAP--NRCECNPGFIPKPKSKSFECQPKCKNGCSNGVCRAPDKCECNKFYEKDIDGNCVPIC 233
            |....|  ..|.|:.|:      |.:.|:.:|..|.....|:  .||:                |
 Frog   156 GALCNPITGACHCSSGY------KGWRCEERCDQGTYGNDCQ--QKCQ----------------C 196

  Fly   234 ENGCVNGNCTAPDVCQCLTGYTKIGHNVCLAVCPEG-----------CQN-GVC-VAPNECSCNA 285
            :||....:.|..  |:|..|||..   .|..:||.|           ||| ||| ....||||.|
 Frog   197 QNGASCDHVTGE--CRCPPGYTGA---FCEDLCPPGKHGSQCEERCPCQNGGVCHHVTGECSCPA 256

  Fly   286 GYTKLEGVCTPVCKDGCVNGFCASPEKCSCNDGYEMDSENRCSPVCSGGCKNGFCVAPGKCSCDE 350
            |:  :..||...|.:|.....|:  ::|.|::|...||                  |.|:|.|..
 Frog   257 GW--MGTVCGQPCPEGRYGRNCS--QECQCHNGGTCDS------------------ATGQCYCSP 299

  Fly   351 GYIKGTGNSCKPICSKGCENGFCDAPEKCSCNDGYEMDGENRCSPVCSGGCKNGFCVAPGKCSCD 415
            ||   .|..|:..|..|.....|  .:.|.|.:|              |.|.:    ..|.|.|:
 Frog   300 GY---NGERCQEECPVGLYGVKC--AQTCQCLNG--------------GKCYH----ISGACLCE 341

  Fly   416 EGYSKETGNSCK-PICSKGCENGFCDAPEKCSCNDGYEMDSENRCSPVCSGGCKNGFCVAPGKCS 479
            .||   ||..|: |:||:|.....||  :||.|:..|...    |.|:            .|:|:
 Frog   342 PGY---TGERCETPLCSEGTYGMKCD--KKCPCHLQYTQS----CHPM------------SGECA 385

  Fly   480 CDEGYSKETGNSCKPICSKGCENGFCDAPEKCSCNDGYEMDGENRCSPVCSGGCKNGFCVAPEKC 544
            |..|.|   |..|...||.|....||.  :.|||.:|.:.|.                  ...||
 Frog   386 CKPGRS---GLYCNETCSLGFYGEFCQ--QICSCQNGADCDS------------------VTGKC 427

  Fly   545 SCDEGYSKETGNSCKPICSNGCENGFCDAPEKCSCNDGYEMDGENRCSPVCSGGCKNGFCVAP-- 607
            .|..|:   ||..|...|..|..                   |.| ||.:|:  |||....:|
 Frog   428 ICAPGF---TGVDCSTACPPGTY-------------------GVN-CSSLCN--CKNNAVCSPVD 467

  Fly   608 GKCSCDEGYSKETGNSCKPICSKGCENGFCDAPEKCSCNDGYEMDSENRCSPVCSGGCKNGFC-I 671
            |.|:|..|:.   |..|...|.:|.....|:.  .|.|.:|      ..|:|:      :|.| .
 Frog   468 GSCTCKAGWH---GVDCSINCPRGSWGLGCNL--TCQCLNG------GACNPL------DGTCTC 515

  Fly   672 APG----KCS--CDEGYSKETGNSCKPICSKGCENGFCDAPEKCSCNDGYEMDSENRCSPVCSGG 730
            |||    ||.  |.:|   ..|.:|...|.....:|...|...|.|..|:   :...|..||.||
 Frog   516 APGWRGLKCELPCQDG---TYGMNCIERCDCSHADGCHPATGYCRCLAGW---AGMHCDSVCPGG 574

  Fly   731 -----------CKNGFCVAP--GKCSCDEGYSKETGNSCKPICSKGCENGFCEAPEKCSCNDGYE 782
                       ||||...:|  |.|.|..||   .|.:|:.|||.|...
 Frog   575 HWGPNCSLSCDCKNGASCSPDDGICECAPGY---RGTTCQRICSPGFYG---------------- 620

  Fly   783 MDGENRCSPVC------SGGCKNGFCIAPGKCSCDEGYSRETGNSCKPICSKG-----------C 830
                :|||..|      :|.|.:    ..|:|.|..|:   .|:.|..:|..|           |
 Frog   621 ----HRCSQACPQCVHSNGPCHH----VTGQCDCLAGF---MGSLCNEVCPSGRYGKNCAGVCAC 674

  Fly   831 -ENGFCDAPE-KCSCNDGYEMDSENRCSPVCSGG-----------CKNG-FCVA-PGKCSCDEGY 880
             .||.|:..: .|.|..|:   ..|.||..|..|           |.|| :|.| .|:|.|..|:
 Frog   675 TNNGTCNPIDGTCQCYPGW---IGNDCSQACPPGHWGPNCIHTCNCHNGAYCSAYDGECKCSPGW 736

  Fly   881 SKETEISCAPFCKDGCVNGLCVSPDFCKCDDGYIFVEESKSCQLDKELLGDYSDCDKNCRNGTCV 945
               |.:.|...|..|.....|..  .|:|.:|                    :|||.       :
 Frog   737 ---TGLYCTQRCPLGYYGKECTL--VCQCQNG--------------------ADCDH-------I 769

  Fly   946 EGICTC--------------SKQYKLHRNEDDNNLICLPICEPECL-NGLCE-FPGSCVC---WD 991
            .|.|||              |..|         ...|..:|  :|| |..|: ..|:|.|   |.
 Frog   770 TGQCTCRTGFMGKFCEQKCPSASY---------GYGCRQVC--DCLNNSTCDHITGTCYCSPGWK 823

  Fly   992 GES----------------------PIDGYSCQSMDSLGSLTGHEKSERHLKWVFITIVSMAFIL 1034
            |..                      |.|.|      .:|::.|          :.|.::.:.|:|
 Frog   824 GARCDQAVMIVVGNLNSLSRTSAAIPADSY------QIGAIAG----------IIILVLVVLFLL 872

  Fly  1035 AIITTMLIIY 1044
            |    :.|||
 Frog   873 A----LFIIY 878

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eater	NP_651533.3	None
megf10	NP_001072726.1	EMI	30..99	CDD:462204	13/72 (18%)