Protein Alignment eater and ltbp3

DIOPT Version :9

• Sequence 1: NP_651533.3
• Gene: eater / 43262
• FlyBaseID: FBgn0243514
• Length: 1074
• Species: Drosophila melanogaster
• Sequence 2: NP_001244070.1
• Gene: ltbp3 / 562912
• ZFINID: ZDB-GENE-060526-130
• Length: 1258
• Species: Danio rerio
• Alignment Length: 1100
• Identity: 254/1100 - (23%)
• Similarity: 370/1100 - (33%)
• Gaps: 392/1100 - (35%)

  Fly    41 CCKGYKKVRSSALRCLAQCKVN--CGSGFC--TKPNV-CTCKKGYVNLNNDPSNRCVP------Y 94
            |.:|||::.|:..:.:.:|.::  |.:|.|  |:.:. ||||.|||....   .|||.      |
Zfish   276 CPQGYKRLNSTHCQDINECMMSGVCWNGECLNTRGSFRCTCKPGYVLKER---TRCVAATVELGY 337

  Fly    95 C--KGCSRGTCQ-------SPGRCICSARHLLDKTTNNCIPQCASGCPNGTCITPNNCSCNKGYK 150
            |  .....|.|:       |...|.|:...........| ||      :||......|...||..
Zfish   338 CFRMVTETGKCEHALSTRLSQEMCCCTVGKAWGSNCERC-PQ------DGTASFNKICPAGKGMS 395

  Fly   151 L-------------------NPTTQ-----------------------------VCLPT------ 161
            |                   ||.|:                             |..||
Zfish   396 LQTYHGTLTFQPFLTSIEHINPDTEVKPPEVPIQTTTPMHLSPISTHGPRRPVIVAKPTTPPIVL 460

  Fly   162 --------------------CKDN--------CA-AVNGFCAAPNRCECNPGFIPKPKSKSFECQ 197
                                ||.|        || ..|||     .|.|.||:.....:|..|.:
Zfish   461 VPPEADSHEVSQTQVSPMDECKLNSNICGHGVCANTQNGF-----MCHCYPGYRSHALTKRCEDE 520

  Fly   198 PKC-KNGCSNGVC---RAPDKCECNKFYE-KDIDG---NCVPICENGCVN-------GNCTAPD- 246
            .:| ...|..|||   ....||.|:..|. .:|..   :|..|  |.|:|       |.|....
Zfish   521 NECDAQPCGRGVCLNVLGSYKCNCHHGYRLSEISSGKRSCSDI--NECLNTEICGVGGQCINQQG 583

  Fly   247 --VCQCLTGY----TKIGH----NVCLA--VCP-EGCQNGVCVAPNEC-SCNAGYTKLEGVCTPV 297
              .|:||.|:    .|..|    |.||.  :|| |.|:|  .:...|| .|..||....|||..:
Zfish   584 SYKCECLPGFRKKIQKPPHCEDINECLEPDICPNEQCEN--TLGSYECLPCQPGYRAERGVCHDI 646

  Fly   298 --CKDG--CVNGFC---ASPEKCSCNDGYEMDSENRCSPVCSGGCKNGFCVAPGKCSCDEGYIKG 355
              ||..  |:||.|   |...:|.||:|:..::..:       ||::
Zfish   647 DECKKHGVCLNGRCENLAGSYRCLCNEGFLPEANRK-------GCRD------------------ 686

  Fly   356 TGNSCKPICSKGCENGFC---DAPEKCSCNDGYEMDGE-NRCSPV--C--SGGCKNGFCV---AP 409
             .|.|:.  ::.|.||.|   |...:|.|..||:...| :.|..:  |  :..|:.|.|:   ..
Zfish   687 -INECQD--NRLCANGHCINTDGSFRCQCYAGYQPTQEGSHCEDINECKRAANCQRGRCINTMGS 748

  Fly   410 GKCSCDEGYSKETGNSCKPICSKGCE--------NGFCDAPE---KCSCNDGYEM-DSENRCSPV 462
            .:|.|.:||:.|.|..||.|  ..|:        :|.|:..:   .|.||||:.: :.::.|..:
Zfish   749 YRCECQKGYTLENGRHCKDI--NECDGERSLCQPHGVCENRQGGYVCVCNDGFRLSEDKHSCEKI 811

  Fly   463 CSG--GC-----KNGFC-------VAPGKCSCDEGYSKETGNSCK-------------PICSKGC 500
            .|.  .|     ...||       |...:|.|..|..  .|:.|:             .:|..|
Zfish   812 ESDKKECYLNLDDTVFCDSVLATNVTKQECCCSIGVG--WGDHCEIYPCPVYRSAEYHSLCPIG- 873

  Fly   501 ENGFCDAPEKCSCNDGYEMDGE-NRCSPVCSGGCKNGFCVAPE---KCSCDEGYSKETG------ 555
             .||....||...  |:....: :.|....:..||.|.|:..:   :|.|.:|:..::.
Zfish   874 -RGFYHDQEKIEY--GFVAHRDIDECVLFSNEICKEGRCMNTQPGFECYCQQGFYYDSNLLECID 935

  Fly   556 -NSC--KPICSNG-CENG------FCDAP-------EKC---------SCNDGYEMDGENRCSPV 594
             :.|  :.:|.|| |.|.      .||.|       :||         .|.|
Zfish   936 VDECHDESLCINGHCVNTRGSFYCVCDPPWVPDAYNKKCVFPTIIGIDECQD------------- 987

  Fly   595 CSGGCKNGFCVAPGKCSCDEGYSKETGNS----CKPICSKGCENGFCDAPEKCSCN--DGYEMDS 653
             ...||||.||             .|.:|    |.|..:...:...|..||:.:..  ....:..
Zfish   988 -PANCKNGQCV-------------NTQDSYYCLCSPPWTLASDRNSCVTPEEQAVMGVSVVHLTD 1038

  Fly   654 ENRCSPVCSGGCKNGFCI-APGKCSCDEGYSKETGNSCKPICSKGCENGFCDAPEKCSCNDG--- 714
            .|.|..  ...|:||.|: .||...|              ||::...  |..|.::|..:|.
Zfish  1039 VNECED--PSYCRNGRCVNTPGSFHC--------------ICTQPLT--FSAALKQCVYDDRTAA 1085

  Fly   715 ------YEMDSENRCS-PVCSGGCKNGFCVAPGKCSCDEGYSKETGNSCK--PICSKGCENGFCE 770
                  .|:|.::.|: |      :|...|...:|.|.  |.:..|..|:  |:.:....|..||
Zfish  1086 HKDICFQEVDEDHMCTMP------RNELTVTYSECCCH--YGRGWGPECRTCPMRNTVLFNRLCE 1142

  Fly   771 APEKCSCNDGYEMDGENRCSPVCSGGCKNGFCIAPGKCSCDEGYSRETGNSCKPICSKGCENGFC 835
            ...:.      |.|||            ..|..|....:.:...|.|..:.|      .|.||.|
Zfish  1143 MHLET------ESDGE------------GDFLAAFSTYNPEGDSSEEDSDEC------SCANGRC 1183

  Fly   836 DAP---EKCSCNDGYEMD-SENRCSPV--CSG------GCKNGFCV---APGKCSCDEGY 880
            ...   ..|.||.|:.:| |..||:.:  |:|      .|||..|:   ...:|.|..|:
Zfish  1184 VRSYLGTMCECNTGFVLDHSRTRCTDIDECAGRGTGQSPCKNARCINTFGSFRCQCKLGF 1243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eater	NP_651533.3	None
ltbp3	NP_001244070.1	EGF_CA	290..>320	CDD:214542	9/29 (31%)
		TB	348..382	CDD:279073	8/40 (20%)
		EGF_CA	562..594	CDD:214542	10/33 (30%)
		EGF_CA	605..640	CDD:214542	13/36 (36%)
		EGF_CA	645..>675	CDD:214542	10/29 (34%)
		EGF_CA	686..726	CDD:214542	12/60 (20%)
		EGF_CA	727..766	CDD:214542	10/38 (26%)
		EGF_CA	767..809	CDD:214542	9/43 (21%)
		TB	828..865	CDD:279073	7/38 (18%)
		EGF_CA	935..>965	CDD:214542	8/29 (28%)
		EGF_CA	982..1012	CDD:214542	12/56 (21%)
		EGF_CA	1038..>1064	CDD:214542	9/41 (22%)
		TB	<1109..1135	CDD:279073	7/27 (26%)
		EGF_CA	1209..>1243	CDD:214542	8/33 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000