DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eater and Dkk4

DIOPT Version :9

Sequence 1:	NP_651533.3	Gene:	eater / 43262	FlyBaseID:	FBgn0243514	Length:	1074	Species:	Drosophila melanogaster
Sequence 2:	NP_001102802.1	Gene:	Dkk4 / 502097	RGDID:	1563172	Length:	221	Species:	Rattus norvegicus

Alignment Length:	227	Identity:	57/227 - (25%)
Similarity:	74/227 - (32%)	Gaps:	76/227 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   471 FCVAPG---------KCSCD-EGYSKETGNSCKPICSKGCENG-FCDA--PEKCSCNDGYEMDGE 522
            ||...|         |.|.| :|..|  |:.|  :..|.|..| ||.|  .|:..|.....:  .
  Rat    12 FCSPLGALVLDFNNIKSSSDVQGSGK--GSQC--VSDKDCNVGKFCFALHDERSFCATCRRV--R 70

  Fly   523 NRC--SPVCSGG--CKNGFCVAPEKC-------------SCDEGYSK----ETGNSCKPICSNGC 566
            .||  |.:|..|  |.|..|.|.|..             :..||.:|    |.....||
  Rat    71 RRCQRSAMCCPGTVCVNDVCTAVENTRPVMDRNTDGQDGTYAEGTTKWPAEENRPQGKP------ 129

  Fly   567 ENGFCDAPEKCSCNDGYEMDGENRCSPVCSGGCKNGFCVAPGKCSCDEGYSKETGNSCKP----- 626
                  :.:|...|.|.|  ||:         |.......||.|.....::|    .|||
  Rat   130 ------STKKSQSNKGQE--GES---------CLRTSDCGPGLCCARHFWTK----ICKPVLLEG 173

  Fly   627 -ICSKGCENGFCDAPE---KCSCNDGYEMDSE 654
             :||:........|||   :|.|..|....|:
  Rat   174 QVCSRRGHKDTAQAPEIFQRCDCGPGLSCRSQ 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eater	NP_651533.3	None
Dkk4	NP_001102802.1	Dickkopf_N	41..91	CDD:282549	16/53 (30%)
Dkk4	NP_001102802.1	Prokineticin	<145..202	CDD:148298	16/60 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900