Protein Alignment eater and DKK3

DIOPT Version :10

• Sequence 1: NP_651533.3
• Gene: eater / 43262
• FlyBaseID: FBgn0243514
• Length: 1074
• Species: Drosophila melanogaster
• Sequence 2: NP_001317149.1
• Gene: DKK3 / 27122
• HGNCID: 2893
• Length: 364
• Species: Homo sapiens
• Alignment Length: 202
• Identity: 46/202 - (22%)
• Similarity: 62/202 - (30%)
• Gaps: 72/202 - (35%)

  Fly   180 ECNPGFIPKPKSKSFECQPKCKNGCSNGVCRAPDKCECNKFYEKDIDGNCVPIC-ENGCVNGNCT 243
            :|.|....:..|..:.|||          ||. .:..|.:      |..|   | :..||.|:||
Human   152 DCGPSMYCQFASFQYTCQP----------CRG-QRMLCTR------DSEC---CGDQLCVWGHCT 196

  Fly   244 APDVCQCLTGYTKIGHNVCLAVCPEGCQNGVCVAPNECSCNAGYTKLEGVCTPVCKDGCVNGFCA 308
            .         ....|.|..:......||.|:|     |:...|.  |..||||:..:|   ..|.
Human   197 K---------MATRGSNGTICDNQRDCQPGLC-----CAFQRGL--LFPVCTPLPVEG---ELCH 242

  Fly   309 SP------------------EKCSCNDGYEMDSENRCSPVCSGGCKNGFCVAPGKCSCDEGYIKG 355
            .|                  ::|.|..|.      .|.|......:.||  .|...|....|:
Human   243 DPASRLLDLITWELEPDGALDRCPCASGL------LCQPHRLPRLEPGF--VPSLPSHSLVYV-- 297

  Fly   356 TGNSCKP 362
                |||
Human   298 ----CKP 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eater	NP_651533.3	None
DKK3	NP_001317149.1	Dkk3_N_Cys1	41..196	CDD:438008	15/63 (24%)
		Dkk3_Cys2	199..278	CDD:438000	21/94 (22%)