Protein Alignment Nep5 and ece2b

DIOPT Version :10

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: XP_073779419.1
• Gene: ece2b / 793465
• ZFINID: ZDB-GENE-131120-140
• Length: 800
• Species: Danio rerio
• Alignment Length: 884
• Identity: 254/884 - (28%)
• Similarity: 416/884 - (47%)
• Gaps: 180/884 - (20%)

  Fly    69 ESANGKQLPYE-PISPNLI-------GIQ--SKFRRSYYHKVVLGGLLALVIILLIAIIVISLGL 123
            |..:|..:|.: .|||:.:       |||  ....|....:|||.||| |..:|.:....::||:
Zfish    27 EEEDGTDVPVDGAISPDSVEVGFRKGGIQLFGPLGRRTQLEVVLAGLL-LASLLALFGCAVTLGV 90

  Fly   124 K----KSSSICRSKECLRTAASLIYAMDEQTDPCEDFYQFTCGRWANEHPRPDS----VTSNDWF 180
            :    .:.|||.::.|:..|:.::.|:|...|||:||||:.||.|..::|.||.    .|.|..:
Zfish    91 RYNRDPARSICLTEACVTVASKIVEALDRSADPCQDFYQYACGGWVRKNPLPDGRSRWSTFNSIW 155

  Fly   181 RERQAHIMRVVREFLRSNITKSEPEAVGKAKTMYRACMDTKLLDKRDLEPLINYLLRFGLPVLPS 245
            .:.||    |::..|.:....|..||..|.::.|.:|::.:.:::...:||::.:.:.|
Zfish   156 DQNQA----VLKHLLENGTFNSSSEAERKTQSYYLSCLNEQRIEELGAQPLMDLITKIG------ 210

  Fly   246 ALNLTLGSGSKYATEAANVKYNWLQSIVSIKQHLTMDLIIGFDVFPDPFNRTINRIALGTPETDS 310
            ..|:         ||:.: |.|:|..:..|.............|..||.|...|.|
Zfish   211 GWNI---------TESWD-KENFLDVLKIISGPYRAQPFFTVSVSVDPKNSNSNVI--------- 256

  Fly   311 AFPFNNDDSHKMLRKIHRKTIFMQNSDDEDDSEDDRESEEEEAAKQTSTGMTAYLHYVRKVIEKY 375
                          ::.:..:|:.:.|                            :|:.|..||.
Zfish   257 --------------QVDQSGLFLPSRD----------------------------YYLNKTNEKV 279

  Fly   376 L-LYVDPNVNQEEATLGITELV---KQGVR-VARKVHEFKEEAENMTKPSKNPAD-DIVY--ITL 432
            | .|:|..|.     ||:  |:   |...| ..:::.:|:....|:|.|.....| :.:|  ||:
Zfish   280 LKAYLDYMVE-----LGL--LLGGDKNSTRGQMQQILDFETALANITVPQDERRDEEKIYHKITI 337

  Fly   433 QDLQNQTDKNIAPKTLPIWVRYMELILKGTRHAGNIQMTQNLTIITSQADITYLQNIVEYLDDTP 497
            .|||     .:||..  .|:.|:..:|...    .:..|:.:.:...:    |:|.:.|.::.|.
Zfish   338 ADLQ-----VLAPAI--EWLDYLNSVLSPL----ELNDTEPVVVYAKE----YMQQVSELINKTD 387

  Fly   498 ASHIESYLFLSTIEELVLHTSSSM---------RLLHSEYMRVAIGTEGS-TPRSLYCANGVNSL 552
            .|.:.:|:    |..||...:||:         :||.|.|     ||:.| |||...|....:..
Zfish   388 HSLLNNYM----IWNLVQKGASSLDQRFENAQDKLLESLY-----GTKKSCTPRWQTCIGNTDDT 443

  Fly   553 LGMAVSYVLADADFTKEK----------LP-------------------KVERMLSDIRRSFDRL 588
            ||.|:..:...|.|.|:.          ||                   :.|.|:::||.:|...
Zfish   444 LGFALGALFVKATFDKQSKEIDLNGGAFLPSCGRNVNSTVHNLMFSVITQAEGMINEIRTAFKGA 508

  Fly   589 VKSTSWMDAATKRKTIQKSAEMKSFIGFPPWLRNASVLNAYYEGAEVNASTHLENLMDFVHWQ-- 651
            :....|||..|::....|:..:...||||.::.::..|:..|:|.||......:|:::|.::.
Zfish   509 LDDLKWMDEQTRQAAKDKADAIYDMIGFPDFILDSKELDDVYDGYEVTEDNFFQNMINFYNFSAR 573

  Fly   652 -MMDKLNEMDKPEPIGWATSPSNVNAFHTFQSNAITVPIAILQYPFYDLG-LEALNYGSIGTILG 714
             |.|:|.:  .|....|:.:|..|||::....|.|..|..|||.|||... .:|||:|.||.::|
Zfish   574 VMADQLRK--PPNRDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYAQDHPKALNFGGIGVVMG 636

  Fly   715 HELTHGFDDSGRRFDRAGNMVEWWSNRTIDEYVNRTECFVEQYSRYHLADIDEYIDGELTLGENI 779
            |||||.|||.||.:|:.||:..||.|.:::.:.|||||.|:||::|.:.  .|:|:|:.||||||
Zfish   637 HELTHAFDDQGREYDKDGNLRSWWQNSSVEAFKNRTECMVDQYTQYTIN--GEHINGKQTLGENI 699

  Fly   780 ADNGGMREAFYAYRLYVKEVGRERSKLPGLEHYSHEQLFFISFGNLWCETYTPAASRYAL-TDSH 843
            |||||::.|::|||.:|::.|.|: :||.: :.:::||||:.|..:||...||.::...| ||.|
Zfish   700 ADNGGLKAAYHAYRSWVQKNGEEK-RLPAV-NLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPH 762

  Fly   844 CPGQMRLRGVLSNSEEFARTFKCARGTPMNPDQPKCRIW 882
            .|.:.|:.|.||||.|||..|:|..|:.||... :|.:|
Zfish   763 SPPKYRVIGTLSNSPEFAEHFQCPLGSSMNSGH-RCEVW 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	M13	151..880	CDD:341056	225/784 (29%)
ece2b	XP_073779419.1	None