Protein Alignment Nep5 and Nepl20

DIOPT Version :10

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_651645.1
• Gene: Nepl20 / 43412
• FlyBaseID: FBgn0039613
• Length: 700
• Species: Drosophila melanogaster
• Alignment Length: 819
• Identity: 214/819 - (26%)
• Similarity: 338/819 - (41%)
• Gaps: 224/819 - (27%)

  Fly   133 KECLR--TAASLIYAMDEQTDPCEDFYQFTCGRWANEHPRPDSVTSNDWFRERQAHIMRVVREFL 195
            ||.:|  .||.:...|:::.|||:|||.|:||.:.               |...|..|||:...:
  Fly    37 KELMRQAKAAEIESFMNQKVDPCKDFYAFSCGNYK---------------RINSALNMRVLTTGV 86

  Fly   196 RSNITK-----------------SEPEAVGKAKTMYRACMDTKLLDKRDLEPLINYLLRFG-LPV 242
            ...:||                 ..||.: :.|..|.:|:..|.|:....|.|...:..|| :|:
  Fly    87 FETLTKGLNRKILKMLNTPHDSHDTPEDI-QVKHFYESCLQIKELNSTYSEKLKRLIAEFGTMPL 150

  Fly   243 LPSALNLTLGSGSKYATEAANVKYNWLQSIVSIKQHLTMDLIIGFDVFPDPFNRTINRIALGTPE 307
            |         .||.:..:    .::||.:...:.....:..|||..|..|..|...|.|.:...|
  Fly   151 L---------EGSSWQED----DFDWLNTTARMAHRYGIMSIIGVGVATDFANNQKNIIYINQQE 202

  Fly   308 TDSAFPFNNDDSHKMLRKIHRKTIFMQNSDDEDDSEDDRESEEEEAAKQTSTGMTAYLHYVRKVI 372
                ||            :..::::|.|                    :|:.....|.:.::.::
  Fly   203 ----FP------------LKTRSMYMDN--------------------ETAIYRQNYQNNIQLIL 231

  Fly   373 EKYLLYVDPNVNQEEATLGITELVKQGVRVARKVHEFKEE-AENMTKPSK--NPADDIVYITLQD 434
            ||||...|             ||.:   :.|:::.||:.: |..:...:|  |..|.|..:|:.:
  Fly   232 EKYLGVKD-------------ELAR---KAAKEMFEFEVDLAHGLVDNNKHLNLRDLIELLTVAE 280

  Fly   435 LQNQ------TDKNIAPKTLPIWVRYMELILKGTRHAGNIQMTQNLTIITSQADITYLQNIVEYL 493
            |:.:      ||               :||.        :.|.:.::....:.:..|.||:||.:
  Fly   281 LRERYAPTLDTD---------------QLIF--------VSMGEKISDKVYEYNRRYQQNLVEVI 322

  Fly   494 DDTPASHIESYLFLSTIEELVLHTSSSMRLLHSEYMRVAIGTEGSTPRSLYCANGVNSLLGMAVS 558
            :.||.|.:.:||||..|.|.:...|                                   |:|..
  Fly   323 ERTPKSTVANYLFLRLIWEFIQKPS-----------------------------------GVAEK 352

  Fly   559 YVLADADFTKEKLPK------------------VERMLSDIRRSFDRLVKST---SWMDAATKRK 602
            ...|..||||....|                  ::.|...::.:|...:.|:   .|::.:|:..
  Fly   353 PTEACVDFTKTYFAKNLDNMIYRRYKNEKSSREIDSMWHQLKSTFKETLLSSPALDWIEPSTRSL 417

  Fly   603 TIQKSAEMKSFIGFPPWLRNASVLNAYYEGAEVNASTH--LENL--MDFVHWQMMDKL-NEMDKP 662
            .|.|...|...:      .|....|...|.|::|....  :|||  :..:..:.|.:| ::..||
  Fly   418 AIAKLEAMTLEV------NNYVKENFTEEFADLNLQNTDCVENLRQVQMLQAKQMRQLYHQPAKP 476

  Fly   663 EPIGWATS--PSNVNAFHTFQSNAITVPIAILQYPFY---DLGLEALNYGSIGTILGHELTHGFD 722
            ...|...|  |||:     ...|:|.||:|:|| |||   |:...|:.:|::..::||||.||||
  Fly   477 LEAGELLSYTPSNI-----LLENSIKVPVALLQ-PFYIWSDVYPNAVMFGTLAYLIGHELIHGFD 535

  Fly   723 DSGRRFDRAGNMVEWWSNRTIDEYVNRTECFVEQYSRYHLADIDEYIDGELTLGENIADNGGMRE 787
            ||||:||..||..:||..::...::.|.:||.:||.||....|.  :.......||||||||||.
  Fly   536 DSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQYGRYVYDGIQ--LKESTAQSENIADNGGMRL 598

  Fly   788 AFYAYR------LYVKEVGRERSK--LPGLEHYSHEQLFFISFGNLWCETYTPAASRYAL-TDSH 843
            |:.|||      |.:....::.:|  ||.| .|:.:|||||||...||....|......: ||.|
  Fly   599 AYTAYRKWYENQLTLPNGAQDMTKETLPNL-RYTAKQLFFISFAQSWCNDVHPKVKALQVSTDDH 662

  Fly   844 CPGQMRLRGVLSNSEEFARTFKCARGTPMNPDQPKCRIW 882
            .||:.|:.|.|||.|||::.|.|..|:.|||.: ||.::
  Fly   663 MPGKFRVIGTLSNFEEFSKEFNCHAGSAMNPIE-KCILY 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	M13	151..880	CDD:341056	207/795 (26%)
Nepl20	NP_651645.1	M13	56..697	CDD:341056	206/795 (26%)