Protein Alignment Nep5 and Nep7

DIOPT Version :10

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Alignment Length: 867
• Identity: 204/867 - (23%)
• Similarity: 351/867 - (40%)
• Gaps: 219/867 - (25%)

  Fly    85 LIGIQSKFRRSYYHKVVLGGLLALVIILLIAIIV-----ISLGLKKSSSIC--RSKECLRTAASL 142
            ::.|.|.||...|.:        |.:.:||.:|:     .|:|.:...:..  .:.:.||:..::
  Fly     1 MLSISSYFRLPLYTR--------LAVCILICVILNDCEARSIGDESHENAITDETADYLRSHGAM 57

  Fly   143 IYA-MDEQTDPCEDFYQFTCGRWAN-------EHPRPD---------SVTSNDWFRERQAHIMRV 190
            :.: |:...|||:|||:|.||.|.|       .|.|.:         .||.....|.:.|..:.|
  Fly    58 MKSYMNFSVDPCDDFYEFACGNWKNVKTPRQSPHRRSNILDISYTLMDVTEQLLTRTKLAEALNV 122

  Fly   191 VREFLRSNITKSEPEAVGKAKTMYRACMDTKLLDKRDLEPLINYLLRFGLPVLPSALNLTLGSGS 255
            ..|.|             .|:..|.:|:..:|..:...:|....::|            :||...
  Fly   123 SAELL-------------VAQRFYNSCLAAELFPRPAADPAYLSVIR------------SLGGFP 162

  Fly   256 KYATEAANV-KYNWLQSIVSIKQHLT---MDLIIGFDVFPD-PFNRTINRIALGTPETDSAFPFN 315
            ....:|.|. .::|.    ::..||:   :..:|..::.|. |||.......||....
  Fly   163 AVDRDAWNASSFSWF----NMSAHLSNYGVRSLIHEEILPQHPFNPYFKLPELGFDHV------- 216

  Fly   316 NDDSHKMLRKIHRKTIFMQNSDDEDDSEDDRESEEEEAAKQTSTGMTAYL---HYVRKVIEKYLL 377
                      :|                         .|...:|...||.   |.:|..:::|
  Fly   217 ----------VH-------------------------TAHVANTSSRAYQLNEHRMRGYLKEY-- 244

  Fly   378 YVDPNVNQEEATLGITELVKQGVRVARKVHEFKEEAENMTKPSKNPADDIVYITLQDLQNQTDKN 442
                |:.::|.:           .|...|..|..||.::....::..|..      ||.::.::
  Fly   245 ----NLTKDEIS-----------AVIEGVFAFWSEALSIEDKFESDRDKC------DLLSEIEE- 287

  Fly   443 IAPKTLPIWVRYMELILKGT-----RHAGNIQMTQNLTIITSQADITYLQNIVEYLDDTPASHIE 502
             .|: ...|..|.|:...|.     ...|..            .|..|::     ||...|.|.|
  Fly   288 -VPR-FGQWRSYYEIAWNGIDFYNGSSGGEF------------CDFYYVE-----LDKVCAKHTE 333

  Fly   503 ---SYLFLSTIEELVLHTSSSMRLLHSEYMRVAIGTEGSTP--RSLYCANGVNSLLGMAVSYVLA 562
               :||              :||.|:....::   .|...|  :.:.|...|...|....:.:..
  Fly   334 AVANYL--------------AMRFLYRMDDKL---KEPKQPEDQKVNCLMIVQMTLPNLFNRLYM 381

  Fly   563 DADFTKEKLPKVERMLSDIRRSFDRLVKSTSWMDAATKRKTIQKSAEMKSFIG----------FP 617
            ...||.||..::..|::::|::..::::|..|:||.|:.:.:.|.|.:...||          ..
  Fly   382 AEHFTDEKHSEISDMVTEMRKAQRQILESVEWLDAETRAEALSKEAGITPVIGSYKNEELSDTLI 446

  Fly   618 PWLRNASVLNAYYEGAEVNASTHLENLMDFVHWQMMDKLNEMDKPEPIGWATSP------SNVNA 676
            ..:.|.:::    ||:...:..:|..|..::|.......:|:.|.      |.|      ..|||
  Fly   447 REINNLTIV----EGSYAQSLINLRVLGTYLHRYAGLHADELPKD------TKPLTLLVGMQVNA 501

  Fly   677 FHTFQSNAITVPIAILQYPFYDLGL-EALNYGSIGTILGHELTHGFDDSGRRFDRAGNMVEWWSN 740
            |:....|::.|...:|..|.|.... ::|.:|:||.::|||||||||..|..||.||.:.:|||.
  Fly   502 FYYNLDNSVYVMAGVLHPPAYHRSWPDSLKFGTIGYLIGHELTHGFDTEGSSFDSAGEVRDWWSR 566

  Fly   741 RTIDEYVNRTECFVEQYSRYHLADIDEYIDGELTLGENIADNGGMREAFYAYRLYVKEVGR---- 801
            ::...:..|.:|:|:.:::|.:.:|::.|.|..|..|||||.||:|.|...||.::|::.|
  Fly   567 KSEAVFQERAQCYVDYFNQYLIPEINQTIRGNETRDENIADAGGLRAALTGYRNHMKQLQRSGAD 631

  Fly   802 ------ERSKLPGLEHYSHEQLFFISFGNLWCETYTPAASRYALTDSHCPGQMRLRGVLSNSEEF 860
                  :..::|||: .|.|||||:.|..|||..|.|......||.:|...:.|:.|.:||:::|
  Fly   632 GETLAHKNEQMPGLD-LSPEQLFFVGFAQLWCADYEPEHYWEELTGAHTVDKYRVLGAVSNNDDF 695

  Fly   861 ARTFKCARGTPMNPDQPKCRIW 882
            |..:||..|:||:|....||:|
  Fly   696 AEVYKCPLGSPMHPKAESCRMW 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	M13	151..880	CDD:341056	187/789 (24%)
Nep7	NP_651603.1	M13	66..715	CDD:341056	187/790 (24%)