Protein Alignment Nep5 and Nepl13

DIOPT Version :9

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 878
• Identity: 174/878 - (19%)
• Similarity: 325/878 - (37%)
• Gaps: 242/878 - (27%)

  Fly   102 LGGLLALVIILLIAIIVISLG-------LKKSSSICRSKE----CLRTAASLIYAMDEQTDPCED 155
            ||.||.|:::..|.:..::..       ::.|.:...|:|    ..:.|..:...|:...|||.|
  Fly     9 LGFLLELLLLFEIQLCDVTEARQNHMNRMQMSGNFPDSREEQLVRQKIATDVQKYMNLSADPCTD 73

  Fly   156 FYQFTCGRWANEHP---RPDSVTSNDWFRERQAHIMRVVREFLRSNITKSEPEA----------- 206
            |:::.||:|...|.   |||.:::.....|.:      :.|.|:..:|:..|..
  Fly    74 FFEYACGQWGRYHKRQLRPDELSTAQQLMETK------ISEQLQQLLTQPLPPQHHPNGYSGASM 132

  Fly   207 --VGKAKTMYRAC--MDTKLLDKRDLEPLINYLLRFGLPVLPSALNLTLGSGSKYATEAANVKYN 267
              |.|.:..|.:|  ::....::|          ||.:.:|..       :|.......:|.::|
  Fly   133 TNVRKVRAFYESCVAVEANASERR----------RFLMKILKD-------NGGLRNVPNSNWQHN 180

  Fly   268 --WLQSIVSIKQHLTMDLIIGFDVFPDPFNRTINRIALGTPETDSAFPFNNDDSHKMLRKIHRKT 330
              |:|::..::::..:|:::|.::
  Fly   181 RQWVQTLGELRRNYGLDILLGLEI----------------------------------------- 204

  Fly   331 IFMQNSDDEDDSEDDRESEEEEAAKQTSTGMTAYLHYVRKVIEKYLLYVDPNVNQEEATLGITEL 395
                                 :...||..|.|.|             :.:|.:....|. ....|
  Fly   205 ---------------------DLNLQTMKGNTIY-------------FGEPKLTIIPAE-HCNAL 234

  Fly   396 VKQGVRVARKVHEFKEE--AENM-------TKPSKNPADDIVYITL--------QDLQNQTDKNI 443
            ..:|.:|..:|:|..::  .||:       |..:...|.||:....        ||:| :.::..
  Fly   235 ATRGAQVRDEVYELVQQQVTENLRDWFGMDTGEAARFAGDIIRFEFELCKQMGEQDIQ-KPEEEF 298

  Fly   444 APKTLPIWVRYMELILKGTR-HAGNIQMTQ-----NLTIITSQADITYLQNIVEYLDDTPASHIE 502
            .|.        ::..:.|.| ..|..::.:     .||.:||:                    :.
  Fly   299 PPA--------IQAQIYGARSRTGQERLRRQKGGMTLTELTSE--------------------MG 335

  Fly   503 SYLFLSTIEELVLHTS--SSMRLLHSEYMRVAIGTEGSTPR------SLYCA-NGVNSLLGMAVS 558
            ::|....:.|::|.:.  |.:.|...||::..:.|..:..|      .||.| |.:|.....|.|
  Fly   336 NHLDFKMLVEVILESQYPSQVYLRSPEYVKHVVRTVKANNRITVGGYILYVALNELNQPPEEAPS 400

  Fly   559 YVLAD-ADFTKEKLPKV-----------ERMLSDIRRSFDRLVKS------TSWMDAATKRKTIQ 605
            ..... ...|:...|:|           :....|:...|:.::|:      ..|||...:|....
  Fly   401 QRARQCVQVTQRLFPQVLGEMFQRHVQRDNAKHDLDAVFNDVIKALEEQFHVEWMDENDRRAART 465

  Fly   606 KSAEMKSFIGFPPWLRNASVLNAYYEGAEVNASTHLENLMDFVHWQMMDKLNEMDKPEPIGWATS 670
            :.::.:  :..|.: ::..:.:..::.:| :....||..:.:...|..:.|...|      :...
  Fly   466 RLSQYR--VSLPDY-QSLDLTDLQFQKSE-DYWRRLEIALKYRSHQQFEALRGND------FGQD 520

  Fly   671 PSNVNAFH-----TFQSNAITVPIAILQYPFYDLGL-EALNYGSIGTILGHELTHGFDDSGRRFD 729
            ...::||.     :.:...:.|...:||.|:|:... ::|.|..:|..|...|...|||.|  ::
  Fly   521 ADGLDAFEVRAALSPRQQMVLVGWGLLQAPYYNYYYPKSLKYALLGHRLASALVQAFDDEG--WN 583

  Fly   730 RAGNMVEWWSNRTIDEYVNRTECFVEQYSRYHLADIDEYIDGELTLGENIADNGGMREAFYAYRL 794
            ........|:..|:..|.|.:||...|||.|...:..|:.:. ..|.|.|||..|:..||.||..
  Fly   584 NHPQATAQWNEVTMSGYRNASECQRAQYSSYLYNEPGEFRNA-TRLREIIADGSGLNLAFNAYLA 647

  Fly   795 YVKEVGRERSKLPGLE-----HYSHEQLFFISFGNLWCETYTPAASRYALTDS-----HCPGQMR 849
            ::::...:...|...|     ::::.|||||.|....|   ....::.|:.||     |.|.:..
  Fly   648 WLEQQDHKLRPLLAKETLSELNFTNTQLFFIYFAQTRC---WAKDNQDAILDSMPLMQHTPERWD 709

  Fly   850 LRGVLSNSEEFARTFKCARGTPMNPDQPKCRIW 882
            :.|.||||.||.|.|.||.|||||... ||.::
  Fly   710 VNGPLSNSAEFGREFGCALGTPMNSGD-KCLVY 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	PepO	146..882	CDD:226118	164/821 (20%)
		M13	151..880	CDD:189000	162/814 (20%)
Nepl13	NP_651096.1	PepO	63..732	CDD:226118	159/812 (20%)
		M13	68..738	CDD:189000	161/814 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920