Protein Alignment Nep5 and Nepl10

DIOPT Version :9

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 849
• Identity: 164/849 - (19%)
• Similarity: 305/849 - (35%)
• Gaps: 301/849 - (35%)

  Fly   104 GLLALVIILLIAII-----VISLGLKKSSSICRSKECLRTAASLIYAMDEQTDPCEDFYQFTCGR 163
            |.|.|:...|:|:.     ::.:.:..|:.|..:             ::..|.||.:|:.|.|||
  Fly     2 GCLLLLCSCLVALFIPIQAIVDINVATSNDIHNN-------------LNRTTSPCTNFWNFACGR 53

  Fly   164 WANEHPRPDSVTSNDWFRERQAHIMRVVREFLRSNITKSE---PEAVGKAKTMYRACMDTKLLDK 225
            :::.....|:      |...:......:.||:.|::.:::   |..:.:.:..|:||.:    |.
  Fly    54 FSSASKYVDN------FERVEDQFATAMVEFMESHLGENDTLAPRLIKQMRQYYKACKE----DT 108

  Fly   226 RDL------EPLINYLLRFGLPVLPSALNLTLGSGSKYATE----AANVKYNWLQSIVSIKQHLT 280
            |.|      |.|:|..      :|.....|..|....:..|    |||....|   ::.::
  Fly   109 RKLHGNPRPEELVNQW------ILHPKKFLVYGLNGVFIDERVDVAANDSMRW---VIQLR---- 160

  Fly   281 MDLIIGFDVFPDPFNRTINRIALGTPETDSAFPFNNDDSHKMLRKIHRKTIFMQNSDDEDDSEDD 345
                     .|||                                                  .|
  Fly   161 ---------MPDP--------------------------------------------------AD 166

  Fly   346 RESEEEEAAKQTSTGMTAYLHYVRKVIEKYLLYVDPNVNQEEA--TLGITELVKQGVRVARKVHE 408
            |.|:                   |:|::...||       |||  ::|:.:||:       |:|:
  Fly   167 RYSD-------------------RRVLQLMRLY-------EEAWYSMGVVKLVE-------KMHQ 198

  Fly   409 FKEEAENMTKPSKNPADDIVYI-TLQDLQNQTDKNIAPKTLPI-WVRYMELILKGTRHAGNIQMT 471
            .:::..     ::.|   :||. :..:|:.:         :|| ...::||:  |..|      |
  Fly   199 LQDKYR-----AEYP---VVYTWSFSELRQE---------IPIPHSFFIELL--GVNH------T 238

  Fly   472 QNLTIITSQ-ADITYLQNIVEYLDDTPASHIESYLFLSTIEELVLHTSSSMRLLHSEYMRVAIGT 535
            :.|..:|.: :|:.||:.....|.|..:...::|:   ...:.||...|..|
  Fly   239 EELYHLTFEVSDVEYLRECFRCLRDFASEPKDTYI---RARQYVLVEESEPR------------- 287

  Fly   536 EGSTPRSLYCANGVNSLLGMAVSYVLADADF--TKEKLPKVERMLSDIRRSFDRLVKSTSWMDAA 598
             ...|||  |.:.:.:.|.:.::|:.....:  .:|...||..:||.::.:|.:      ::||.
  Fly   288 -ERNPRS--CIHHMRAYLPLGMNYIYDRFIYQNREEDTSKVLEILSTLKAAFGQ------YLDAN 343

  Fly   599 TKRKTIQKSAEMKS-------FIGFPPWLRNASVLNAYYEGAEVNASTHLENLM----------- 645
            ..:.|..:.|.:::       .||..|..::....|.:|..|..:|:..|.||:
  Fly   344 RLQLTPNQLAYVRAKLEGIQIKIGNLPEEKSPEFYNNHYGSANFSATNFLANLLEAFALRTRLQN 408

  Fly   646 ----------DFVHWQMMDKLNEMDKPEPIGWATSPSNVNAFHTFQSNAITVPIAILQYPFYDLG 700
                      |..|:.:.|.:.:.        .|||     |:..:.|.||||:..||:|.:|..
  Fly   409 AGLLARNSRVDLRHYYVNDNVRKA--------RTSP-----FYENERNTITVPMEFLQWPLFDHR 460

  Fly   701 LEAL-NYGSIGTILGHELTHGFDDSGRRFDRAGNM----VEWWSNRTIDEYVNRTECFVEQYSRY 760
            ...: .:..:|.:||||:.|.|:..|..||.|||.    :|...::...:.:   :|..||
  Fly   461 EHTIFQHSLLGAVLGHEMNHAFEQEGILFDAAGNESPVGLEIRESKPFRDAI---KCAEEQ---- 518

  Fly   761 HLADIDEYIDGELTLGENIADNGGMREAF------------YAYRLYVKEVGRERSKLPGLEHYS 813
                      ..::|.|.:||..|::.|:            :.||.|..|           :.::
  Fly   519 ----------PFVSLKERLADLNGLQLAYDAFFGLAHDSRQFEYRPYAFE-----------QEFT 562

  Fly   814 HEQLFFISFGNLWCETYTPAASRYALTDSHCPGQMRLRGVLSNSEEFARTFKCARGTPMNPDQPK 878
            ..|||.:|:...:|.:..|..       :|.....|:...:.|..:||..|.|    ..:|.. .
  Fly   563 APQLFHLSYAQFFCGSLPPVI-------AHDRDDERVNVSVGNLRQFAYDFNC----ETSPSS-V 615

  Fly   879 CRIW 882
            |.:|
  Fly   616 CEMW 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	PepO	146..882	CDD:226118	156/800 (20%)
		M13	151..880	CDD:189000	154/793 (19%)
Nepl10	NP_610787.1	GluZincin	41..608	CDD:301352	152/779 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920