Protein Alignment Nep5 and Nepl6

DIOPT Version :9

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 798
• Identity: 145/798 - (18%)
• Similarity: 278/798 - (34%)
• Gaps: 222/798 - (27%)

  Fly   137 RTAASLIYAMDEQTDPCEDFYQFTCGRWANEHPRPDSVTSNDWFRERQ--AHIMRVVREFLRSNI 199
            |...:::..:.|.:..|..::|:.||::|..| |.|..|......:.:  .::::::.|..:.:.
  Fly    28 RLMNNILSYVAEDSSACGTYFQYACGKYAVRH-RDDPFTEIIQMLDHKVNGNLVQLMHELHQRSQ 91

  Fly   200 TKSEPEAVGKAKTM--YRACMDTKLLDKRDLEPLINYLLRFGLPVLPSALNLTLGSGSKYATEAA 262
            :....|:..:||.:  ||.|        |:..|....:..: |.:.|....||............
  Fly    92 SPGFNESSVEAKVLHFYRTC--------REAPPSTRKMEHY-LRLAPPGQALTWPQFMPRGEPWP 147

  Fly   263 NVKYNWLQSIVSIKQHLTMDLIIGFDVFPDPFNRTINRIALGTPETDSAF-------PFNNDDSH 320
            ..::.|::|:..:.::       ||.      |..:|.:.|.:.|..:.|       ....|..|
  Fly   148 KAQFKWMKSLGHLYRY-------GFT------NVLVNVLVLRSSENSNRFRLDISMPSLEGDAQH 199

  Fly   321 ----------------------KMLRKIHR-----KTIFMQNSDDEDDSEDDRESEEEEAAKQTS 358
                                  .::|||.|     :.:...:.|||.::...|:.|.:
  Fly   200 LGGFLSTLATLQIIGVPTKSILPLVRKIRRLESAIRVLTEVDDDDESETWTLRQWEYK------- 257

  Fly   359 TGMTAYLHYVRKVIEKYLLYVDPNVNQEEATLGITELVKQGVRVARKVHEFKEEAENMTKPSKNP 423
            ||. |:..:|..::                          |..|:   |.:..:|:|..
  Fly   258 TGY-AWQGFVESIV--------------------------GHSVS---HHYVMQAQNAK------ 286

  Fly   424 ADDIVYIT-LQDLQNQTDKNIAPKTLPIWVRYMELILKGTRHAGNIQMTQNLTIITSQADITYLQ 487
                 |.| |:.|.:.||..:....  |..|::..::...     |...:::..:|   |:....
  Fly   287 -----YFTGLKRLMDSTDAEVVANY--IMTRFVLYLIDDF-----IDSNEHIDCVT---DMRRNM 336

  Fly   488 NIVEYLDDTPASHIESYLFLSTIEELVLHTSSSMRLLHSEYM------RVAIGTEGSTPRSLYCA 546
            |:...|     .:.|.:|..:|:::.....:.....|..:::      |:.:.:|
  Fly   337 NLASNL-----LYKERFLDPATLQQYTQEVTKVFEQLRRQFLLQINENRLGLTSE---------- 386

  Fly   547 NGVNSLLGMAVSYVLADADFTKEKLPKVERMLSDIRRSFDRLVKSTSWMDAATKRKTIQKSAEMK 611
              .||::.....:|:.:..    .||:.....|.:.|.::.||......|.|.:
  Fly   387 --QNSMVATKAQHVVLNIG----NLPRGRDHRSFVSRHYEDLVFPLPDFDYARE----------- 434

  Fly   612 SFIGFPPWLRNASVLNAYYEGAEVNASTHLENLMDFVHWQMMDKLNE-MDKPEPIGWATSPSNV- 674
                                        || ||::|...:.:.:||: ...|:...:.:.|...
  Fly   435 ----------------------------HL-NLLEFRTRKQVLQLNQSAPTPDEFFYLSDPKTAM 470

  Fly   675 --NAFHTFQSNAITVPIAILQYPFYDL-GLEALNYGSIGTILGHELTHGFDDSGRRFDRAGNMVE 736
              ..::..:.|.|.||..:||.||:.. ..:...|..:|.:|.|||.|..|..|..:||.||:.|
  Fly   471 SSGPYYLMRLNIIVVPHGLLQEPFFAADSHDIFKYSLLGFVLAHELMHSVDTVGLYYDRYGNIHE 535

  Fly   737 WWSN-RTIDEYVNRTECFVEQYSRYHLADIDEYIDGELTLGENIADNGGMREAFYAYRLYVKEVG 800
            .... .:...:|...:|.....::|              |.|.|||..|:.   .||..|.:  .
  Fly   536 IGPQISSSPRFVAGLQCLNRNSTQY--------------LDERIADIAGLD---LAYSTYFQ--N 581

  Fly   801 RERSKLPGLEHYSHEQLFFISFGNLWCETYTPAASRYALTDSHCPGQMRLRGVLSNSEEFARTFK 865
            ..:..|........:|:||::....:|....|.  .:.   .|...:.||:.:|:....|...|.
  Fly   582 SSQMSLTDFTTIPPQQIFFLNLAQFFCGDGDPI--NFV---GHDNDETRLQQMLNGFAPFHEAFG 641

  Fly   866 CARGTPMNPDQP-KCRIW 882
            |    |...:|| ||::|
  Fly   642 C----PAKSNQPEKCQLW 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	PepO	146..882	CDD:226118	143/787 (18%)
		M13	151..880	CDD:189000	141/780 (18%)
Nepl6	NP_609023.3	M13	42..653	CDD:189000	141/780 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910