Protein Alignment Nep5 and goe

DIOPT Version :9

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_001285350.1
• Gene: goe / 32660
• FlyBaseID: FBgn0027528
• Length: 879
• Species: Drosophila melanogaster
• Alignment Length: 930
• Identity: 183/930 - (19%)
• Similarity: 311/930 - (33%)
• Gaps: 259/930 - (27%)

  Fly    53 GNGNATANGHGQNSATESANGKQ---LPYEPISPNLIGIQSKFRRSYYHKVVLGGLLALVIILLI 114
            |.|..|......||...||||.:   ||.......|:.:..|.|..|.....|..||.|:||||:
  Fly    84 GAGGRTPAAITPNSTHPSANGLRALLLPGRRSFDALMSLSRKRRILYVTTACLCALLLLIIILLL 148

  Fly   115 AI---IVISLGLKKSSSICRSKECLRTAASLIYAMDEQTDPCEDFYQFTCGRWANEHPRPD--SV 174
            |.   :...|    .:.:|..|||:.::..|:...:....||.:.|::.||.:|:::...:  .:
  Fly   149 AFWPEVPFYL----RAPLCLDKECVESSRQLLLWANTSKSPCHETYEWACGNFASDYANHEYFVI 209

  Fly   175 TSNDW----FRERQAHIMRVVREFLRSNITKSEPEAVGKAKTMYRACMDTKLLDKRDLEPLINYL 235
            ...:|    :.|.|.  :..:..|:.......|........::||:|.:|.:|||...:.|
  Fly   210 KRGEWNYETYNEYQE--LNELNRFIAMLPNSQEGSVESTVSSLYRSCRETDVLDKSQSDLL---- 268

  Fly   236 LRFGLPVLPSALNLTLGSGSKYATEAANVKYNW--------LQSIVSIKQHLTMDLIIGFDVFPD 292
                   |..|:|...|   ..|...:|...:|        ||:...|..:..:.:..||. .|.
  Fly   269 -------LKRAINAVYG---WQAFRDSNRLQSWEYKRVLVVLQAKHGIFPYYRVTVENGFS-NPH 322

  Fly   293 PFNRTINRIALGTPETDSAFPFNNDDSHKMLRKIHRKTIFMQNSDDEDDSEDDRESEEEEAAKQT 357
            .:..|::...||.|:                      ..|..|..||:
  Fly   323 DYVITLDEGELGLPD----------------------KYFYGNDADEE----------------- 348

  Fly   358 STGMTAYLHYVRKVIEKY-LLYVDPNVN----QEEATLGITELVKQGVRVARKVHEFKEEAENMT 417
                         |:..| ||..|..:|    ..||.|...::.....|:...:.:.|.:|   .
  Fly   349 -------------VVRGYKLLLRDFAINMGIVSREADLFADDIFHYERRIVNHIEDAKADA---N 397

  Fly   418 KPSKNPADDIVYITLQDLQNQTDKNIAPKTLPIWVRYMELILKGTRHAGNIQMTQNLTIITSQAD 482
            :|            :..|....|..|...:||| :..::.|...|:      :|::..::....:
  Fly   398 RP------------INKLMRLADLKIKAPSLPI-LESLQAIFPKTK------ITEDTEVLVRDPE 443

  Fly   483 ITYLQNIVEYLDDTPASHIESYLFLSTIEELVLHTSSSMRLLHSEYMRVAIGTEGSTPRSLYCAN 547
            :.:..:::  |..:....|.:::..|...:::.|.|...|.|...:.....|...|.||.|.|:.
  Fly   444 VMHALSVL--LSTSDKKPINNFIVWSLARKMLPHLSKEYRTLAETFDHALYGRTASYPRWLICSK 506

  Fly   548 GVNSLLGMAVSYVLADADFTKEKLPK----------------------VERMLSDIRRSFDRLVK 590
            .|...|..||       |..:::.|:                      ::.|...:|......::
  Fly   507 VVRDWLPFAV-------DALQQQPPRQQFETMTSKSRGLNKTQGNEELLKLMFFSLRNQLKDSLE 564

  Fly   591 STSWMDAATKRKTIQKSAEMKSFIGFP-PWLRNASVLNAYYEGAEVN---ASTHLENLMDFVHWQ 651
            ...|::.|.::...:|..||:...|.| ..|:..:.|..||....:|   ...|||.:..|...|
  Fly   565 QAKWLEPAARQFIQKKLNEMRLQFGIPDEVLQQPTYLAQYYNELILNNVFFVEHLEWIWTFRRSQ 629

  Fly   652 MMDKL----------NEM---DKPEPIGWATSPSNVNAFHTFQSNAITVPIAILQYPFYDLGLE- 702
            |..||          :||   |.|:.|.::.           :.|.:.|...::...:||....
  Fly   630 MEKKLGPLAILDVIVSEMYTRDNPQAIAYSN-----------KLNMLLVSKVLISSNYYDYRYPV 683

  Fly   703 ALNYGSIGTILGHELTHGFDDSGRRFD-----------------------RAG-------NMVEW 737
            |:|:..|||.:...|...|.....:|:                       .||       .:.|.
  Fly   684 AVNFARIGTDILEALIDNFSTFLLQFNTQSTDISDAAPEIRYAQPDVNCLAAGQPPRLVHELNEL 748

  Fly   738 WSN----------------RTIDEYVNRTECFVEQYSRYHLADIDEYIDGELTLGENIADNGGMR 786
            .||                |.:..:||..:.                  |....|..| |.....
  Fly   749 SSNALKSFHVTLSAARTAARALSNFVNAIDA------------------GSAIQGSGI-DQANTY 794

  Fly   787 EAFYAYRLYVKEVGRERSKLPGLEHYSHEQLFFISFGNLWCETYTPAASRYA----LTDSHCPGQ 847
            ||....|         |.::|||..::..:||.:|:....|.| |.|...||    |.:|.....
  Fly   795 EALGLTR---------RLRIPGLRSFNENELFTLSYMQQHCST-TIADKDYARIKPLVESQLAES 849

  Fly   848 MRLRGVLSNSEEFARTFKCA 867
            ........:.:...|:..||
  Fly   850 YLFNATWQHIQFLPRSTNCA 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	PepO	146..882	CDD:226118	153/831 (18%)
		M13	151..880	CDD:189000	153/826 (19%)
goe	NP_001285350.1	GluZincin	184..>694	CDD:301352	117/620 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910