Protein Alignment Nep5 and Nep6

DIOPT Version :10

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_572831.2
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 850
• Identity: 190/850 - (22%)
• Similarity: 305/850 - (35%)
• Gaps: 262/850 - (30%)

  Fly    99 KVVLGGLLALVIILLIAIIVISLGLKKSSSICRSKECLRTAASLIYAMDEQTD----PCEDFYQF 159
            |..|..:..||:||.:.::          .:..:::|.:       .:|..||    |||:|:|:
  Fly     2 KPPLSSITRLVVILGVMLL----------KLAAAQDCQQ-------QLDNDTDAEVKPCENFHQY 49

  Fly   160 TCGRWANEHPRPDSVTSNDWFRERQAHIMR----------VVREFLRSNIT------KSEPEAVG 208
            .||.|          .||...|...||.||          ::|....|:.|      .|...:..
  Fly    50 ACGNW----------YSNTSQRILGAHDMRSKWVANLKLQLIRYLEESSSTDSFSANTSVTTSTA 104

  Fly   209 KAKTMYRACMDTKLLDKRDLEPLINYLLRFGLPVLPSALNLTLGSGSKYATEAA----------- 262
            :..|:||.|    ||..:.:....:.|.|.|.. .|...|.|.||.......||
  Fly   105 QLGTLYRCC----LLSGQSIRTYTDALSRSGAN-FPLLANHTGGSFDWVLANAALRTYGAQGLWR 164

  Fly   263 -NVKYNWLQSIVSIKQHLTMDLIIGFDVFPDPFNRTINRIALGTPETDSAFPFNNDDSHKMLRKI 326
             .||.||    .|..|.:       |.:.|..|:      .||          .:|:.::.|.:.
  Fly   165 LLVKDNW----QSADQRI-------FYMLPPKFD------LLG----------RDDELNEFLYQR 202

  Fly   327 HRKTIFMQNSDDEDDSEDDRESEEEEAAKQTSTGMTAYLHYVRKVIEKYLLYVDPNVNQEEATLG 391
            :.|.:.::                                                       ||
  Fly   203 YLKILLLE-------------------------------------------------------LG 212

  Fly   392 ITELVKQGVRVARKVHEFKEEAENMTKPSKNPADDIVYI----TLQDLQNQTDKNIAPKTLPIWV 452
            :.  |::...:|.|:..|:   :::.|...|.|:..:.:    :|:||::|..:      |.: .
  Fly   213 LR--VRRAALLAEKLVAFE---KSLQKLLPNDAEQTLVLRKPQSLKDLESQLPR------LEL-K 265

  Fly   453 RYMELILKGTRHAGNIQMTQNLTIITSQADITYLQNIVEYLDDTPASHIESYLFLSTIEELVLHT 517
            ||.|.||:|      |.......::.  ||:.|||.:...|    |.|....:.|||...|.|..
  Fly   266 RYFETILEG------IDWDSKTLLLV--ADLDYLQGLQRLL----AEHTSDPMVLSTWLLLQLPA 318

  Fly   518 SSSMRLLHSEYMRVAIGTEGSTPRSLYCANGVNSL----LG-MAVSYVLADA--DFTKEKLPKVE 575
            ...:||...:    .:|.:.:     :|...:..|    || :.:..||.::  |.....:.::.
  Fly   319 YFELRLHDDD----KLGNQRN-----HCLEQLRKLMPGQLGRLQMQLVLGESYQDVYDTAIQQIA 374

  Fly   576 RMLSDIRRSFDRLVKSTSWM--DAATKRKTIQKSAEMKSFI--------GFP--PWLRNASVLNA 628
            .:..|:::.|:.::..|...  |..|:.....|...|:...        |.|  |.|
  Fly   375 VLFRDLKQQFELVLNETEVFNEDLVTRNLARDKLRAMRLLTPRLQDPINGGPGTPQL-------- 431

  Fly   629 YYEGAEVNASTHLENLMDFVHWQMMDKLNEMDKPEPIGWATS----PSNVNAFHTFQSNAITVPI 689
               |...:|     ||:.....|...:..:: ..||:   ||    |.:|||::..:.|.|.:|:
  Fly   432 ---GGNCDA-----NLLQLSLSQAKLEYRQV-FGEPV---TSVPADPLSVNAYYRLKLNRIELPL 484

  Fly   690 AILQYPFY------DLGLEALNYGSIGTILGHELTHGFDDSGRRFDRAGNMVE-WWSNRTIDEYV 747
            .::..|..      :....|.....:|.||.||:.|.||..|..:|..|.:.. .||.|.|..:.
  Fly   485 GLMATPLIQQQCSKEADTRAKLSAGLGYILAHEMVHAFDLDGLNYDATGQLANGQWSARAIIRFG 549

  Fly   748 NRTECFVEQYSRYHLADIDEYIDGELTLGENIADNGGMREAFYAYRLYVKEVGRERSKLPGLEHY 812
            .|..|::..          .|.:..||:.|||||..|:|.|...|        |.||....|
  Fly   550 LRAGCYLGV----------RYSNATLTVNENIADTEGLRLALDTY--------RHRSGATNL--- 593

  Fly   813 SHEQLFFISFGNLWCETYTPAASRYALTDSHCPGQMRLRGVLSNSEEFARTFKCARGTPMNPDQP 877
               :.||::|...||.|   .||...|: .|.....|:..|:.|..||..||:|...:.|||..
  Fly   594 ---RTFFVAFAQNWCGT---VASTSGLS-QHAGHAERVNNVVGNMPEFGDTFECKATSQMNPVN- 650

  Fly   878 KCRIW 882
            ||.||
  Fly   651 KCHIW 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	M13	151..880	CDD:341056	178/794 (22%)
Nep6	NP_572831.2	M13	40..653	CDD:341056	177/791 (22%)