Protein Alignment Nep5 and Kel

DIOPT Version :10

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_001178540.1
• Gene: Kel / 297025
• RGDID: 1565470
• Length: 713
• Species: Rattus norvegicus
• Alignment Length: 812
• Identity: 178/812 - (21%)
• Similarity: 320/812 - (39%)
• Gaps: 162/812 - (19%)

  Fly   105 LLALVII-LLIAIIVISLGLKKSSS--ICRSKECLRTAASLIYAMDEQTDPCEDFYQFTCGRWAN 166
            |||:::. |||...::.:.:.::..  .|.|..|:......:.:.:....||.||:.|.|.: ||
  Rat    30 LLAVLLCGLLIGCSMLWVYIFRNCGPWTCESPVCMELVNHYLASGNRSAAPCTDFFSFACEK-AN 93

  Fly   167 EHPRPDSVTSNDW---FRERQAHIMRVVREFLRSNITKSEPEAVG---------KAKTMYRACMD 219
            .       |||.:   ..|.::.:.:::             ||.|         ||...|.:|||
  Rat    94 G-------TSNSFQALAEENKSRLWKLL-------------EAPGSWHLESGEEKAFQFYNSCMD 138

  Fly   220 TKLLDKRDLEPLINYLLRFGLPVLPSALNLTLGSGSKYATEAANVKYNWLQSIVSIKQHLTMDLI 284
            |..::.....||:..:...|                     ..|:..||
  Rat   139 TDAIEASGTGPLVQIIKELG---------------------GWNISGNW---------------- 166

  Fly   285 IGFDVFPDPFNRTINRIALGTPETDSAFPFNNDDSHKMLRKIHRKTIFMQNSDDEDDSEDDRESE 349
                .|.| ||:.:..:.    .....|||.....|......|...|.:      |..|.|...:
  Rat   167 ----TFFD-FNQNLRLLM----SQYGHFPFFRAYLHPHPAPPHTPIIQI------DQPEFDILLQ 216

  Fly   350 EEEAAKQTSTGMTAYLHYVRKVIEKYLLYVDPNVNQEEATLGITELVKQGVRVARKVHEFKEEAE 414
            :::..|..:..:..|:.|:.::  ..||..:|...|:.|:..|.               |.....
  Rat   217 QDQEQKVYAQILREYVTYLNRL--GTLLGSNPQEAQQHASWSIV---------------FTSRLF 264

  Fly   415 NMTKP-SKNPADDIVY--ITLQDLQNQTDKNIAPKTLPIWVRYMELILKGTRHAGNIQMTQNLTI 476
            ...:| .:..|.|.::  :|:..||     .:||..  .|:..::.|....    ::..:|.|.:
  Rat   265 QFLRPQQQQQAQDKLFHVVTIDALQ-----EMAPAI--DWLSCLQAIFTPM----SLSPSQTLQV 318

  Fly   477 ITSQADITYLQNIVEYLDDTPASH---IESYLFLSTIEEL--VLHT---------SSSMRLLHSE 527
                .|:.||:|:.:.:::...:|   |:||:.|..::.|  .|.|         :..:|.|...
  Rat   319 ----HDLDYLRNMSQLVEEGLLNHSEIIQSYMILGLVDTLSPALATKFQEARRELTQKLRKLKER 379

  Fly   528 YMRVAIGTEGSTPRSLYCANGVNSLLGMAVSYVLADADFTKEKLPKVERMLSDIRRSFDRLVKST 592
            ....|.      ||.:.|.....|.....::.:.....|..........:.::|:.:....:|..
  Rat   380 PPLPAY------PRWMKCVEQTGSFFEPTLAALFVHEAFGPSIRSAAMELFAEIKDAVIVRLKKL 438

  Fly   593 SWMDAATKRKTIQKSAEMKSFIGFPPWLRNASVLNAYYEGAEVNASTHLENLMDFVHWQMMDKLN 657
            ||:...|:::.:.|..:::..:|.|.......:....|...::..| .|::.:..|......|:.
  Rat   439 SWISEETRKEALNKLTQLQVEMGAPKRALKTEMAKQEYSDIQLGPS-FLQSFLSCVRSLQGRKVR 502

  Fly   658 EMDKPEPI-GWATSPSNVNAFHTFQSNAITVPIAILQYPFYDLGL-EALNYGSIGTILGHELTHG 720
            ...:|.|. .|..||.:|:|:::...:.:..|..:||.||:..|. .|:|:|::|:|:.|:|.|.
  Rat   503 SFLQPFPYHRWQKSPWSVSAYYSVPDHVVVFPAGLLQPPFFHPGYPRAVNFGAVGSIMAHKLLHI 567

  Fly   721 FDDSGRRFDRAGNMVEWWSNRTIDEYVNRTECFVEQYSRYHLADIDEYIDGELTLGENIADNGGM 785
            |    .:|...|.... ...|.:.|.:   .|...:|:.:.|..:..: :|..||.||.||.||:
  Rat   568 F----FQFLLPGGCPA-CDTRALQEAL---LCLEHRYAAFPLPSMSSF-NGSHTLLENAADIGGV 623

  Fly   786 REAFYAYRLYVKEVGRERSKLPGLEHYSHEQLFFISFGNLWCETYTPAASRYALTDSHCPGQMRL 850
            ..||.|||..:.|...|.: ||..| .|..||||.|:..:.|........:    |:|.|.::|:
  Rat   624 AIAFQAYRKRITERTGELT-LPNQE-LSPYQLFFRSYAQVMCRELISQDPQ----DTHSPPRLRV 682

  Fly   851 RGVLSNSEEFARTFKCARGTPMNPDQPKCRIW 882
            .|.||||.:||:.|.|..|:.:|| ..:|::|
  Rat   683 HGPLSNSPDFAKHFLCPSGSLLNP-STRCKLW 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	M13	151..880	CDD:341056	167/759 (22%)
Kel	NP_001178540.1	M13	78..711	CDD:341056	167/760 (22%)