Protein Alignment Nep5 and nep-25

DIOPT Version :9

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_495164.2
• Gene: nep-25 / 191543
• WormBaseID: WBGene00022874
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 571
• Identity: 111/571 - (19%)
• Similarity: 189/571 - (33%)
• Gaps: 172/571 - (30%)

  Fly   352 EAAKQTSTGMTAYLHYVRKVIEKYLLYVDPNVNQEEATLGITELVKQGVRVARKVHEFKEEAENM 416
            |...:...||.|.........:|:         :.|....|.|.:||     ..:.:.|.|.
 Worm    61 EDLSKLKAGMVAKYRKKHPKFDKF---------KGEDAFAIAEALKQ-----LNIEQLKSEC--- 108

  Fly   417 TKPSKNPADDIVYITLQDLQNQTDKNIAPKTLPIWVRY-----MELILKGTRHAGNIQ-MTQNLT 475
             |||| |.....:|:.||  |:|.:|:.....|.:..|     ..:|:|   ..|.|: .|...:
 Worm   109 -KPSK-PRLSSFFISAQD--NRTIENVDEVLFPGFENYPCEEKAAIIIK---EVGEIEDYTTTRS 166

  Fly   476 IITSQADITYLQNIVEYLD-------------------DTPASH----IESYLFLSTIEELVLHT 517
            ::.|..:......:||.||                   .||.:.    ||.|  :..:..:...|
 Worm   167 VLVSAVNGFITSKLVEKLDVKARKLFNKFKSVISKEIIKTPWAKNYKAIEQY--VEALSNITFRT 229

  Fly   518 SSSMRLLHSEYMRVAIGTEGSTPRSLYCANGVNSLLGMAVSYVLADADFTKEKLPKVERMLSDIR 582
            .:.:|:...:.|.:...||....:.          |.:|.|...|:.........|.|.:|
 Worm   230 FADVRITVKKSMELYESTEKDCRKK----------LDVAFSQPTAELVCKGVATRKAEELL---- 280

  Fly   583 RSFDRLVKSTSWMDAATKRKTIQKSAEMKSFIGFPPWLRNASVLNAYYEGAEVNASTHLENLMDF 647
               |..::.....|.|...|.:
 Worm   281 ---DEPIEDIFPQDQAGILKDV------------------------------------------- 299

  Fly   648 VHWQMMDKLNEMDKPEPIGWATSPSNVNAFHTFQSNAITVPIAILQYPFY-DLGLEALNYGSIGT 711
              |||   .|..|....||        |.|           :.:|...:: ||      |||||.
 Worm   300 --WQM---FNSFDNSVYIG--------NEF-----------LLLLNTDYFSDL------YGSIGF 334

  Fly   712 ILGHELTHG--FDDS------GRRFDRAGNMVEWWSNRTIDEYVNRTECFVEQYSRYHLADIDEY 768
            .:.||:.|.  |||:      .:.:.:..:.|:..:.:|.:.:...||          :.::...
 Worm   335 SMIHEIMHTLVFDDNDLDKPLSKLWTKNADCVKDQALKTCETFPTVTE----------MHNMKPA 389

  Fly   769 IDGELTLGENIADNGGMREAFYAYRLYVKEVGRERSKLPGLEHYSHEQLFFISFGNLWCETYTPA 833
            .:..:|..|:.||....|   .|:|:|.....| ::.:|..|....:||||......:|.  ...
 Worm   390 CNTTVTFEEDAADLAAYR---IAWRIYENSYAR-KTVVPNYEALDKKQLFFYGAAVFFCN--QDG 448

  Fly   834 ASRYALTD-SHCPGQMRLRGVLSNSEEFARTFKCARGTPMNPDQPK-CRIW 882
            .||....: :|.....|:..::|..::|:..|||.....|..::.| |.::
 Worm   449 MSRVPFQNLAHSNNYQRVNSLMSQMKQFSDAFKCKPTDKMITNRAKHCELY 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	PepO	146..882	CDD:226118	111/569 (20%)
		M13	151..880	CDD:189000	110/567 (19%)
nep-25	NP_495164.2	Peptidase_M13	308..496	CDD:279739	49/228 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910