Protein Alignment Nep5 and nep-2

DIOPT Version :9

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_494343.2
• Gene: nep-2 / 188090
• WormBaseID: WBGene00020230
• Length: 736
• Species: Caenorhabditis elegans
• Alignment Length: 825
• Identity: 231/825 - (28%)
• Similarity: 366/825 - (44%)
• Gaps: 163/825 - (19%)

  Fly   105 LLALVIILLIAIIVISLGLKKSSSICRSKECLRTAASLIYAMDEQTDPCEDFYQFTCGRWANEHP 169
            ||.|.:::|.|.|...:..|.||.:|.|..|::||:.::.:|:...|||:|||:|.||:|...||
 Worm    28 LLILFLLVLGAAIYFYINYKDSSDVCLSPGCIKTASVILSSMNSSVDPCDDFYEFACGQWIKGHP 92

  Fly   170 RPDSVTSNDWFRERQAHIMRVVREFLRSNITKSEP-----EAVGKAKTMYRACM-DTKLLDKRDL 228
            .||...|...|......:...::|.|..|   .||     .||||||..|..|: ::::||
 Worm    93 IPDDAPSVSNFENLGQDLEFALKELLDEN---DEPYDYETSAVGKAKYFYNLCLNESEILD---- 150

  Fly   229 EPLINYLLRF--------GLPVLPSALNLTLGSGSKYATEAANVKYNWLQSIVSIKQHLTMDLII 285
                |:...|        |.|.|...:.........||...|..|               .|.:.
 Worm   151 ----NWRTTFDEVVKSFGGWPSLGHQMKPDASIEMLYADMVAKFK---------------ADSLF 196

  Fly   286 GFDVFPDPFNRTINRIALGTPETDSAFPFNNDDSHKMLRKIHRKTIFMQNSDDEDDSEDDRESEE 350
            ...|.||.                     .|...|.:|....:..:|.:      |.....|:||
 Worm   197 KATVQPDD---------------------KNSQRHVLLIDQPQLNLFAR------DFYVAAENEE 234

  Fly   351 EEAAKQTSTGMTAYLHYVRKVIEKYLLYVDPNVNQEEATLGITELVKQGVRVARKVHEFKEEAEN 415
            .          .|||..:|.|    |:.:|  .::..|||...|::           :|:....|
 Worm   235 R----------MAYLQLIRDV----LILLD--ADRTRATLDAKEII-----------DFETALAN 272

  Fly   416 MTKPSKNP---ADDIVYITLQDLQNQTDKNIAPKTLP--IWVRYMELILKGTRHAGNIQMT---- 471
            :|...::.   |:....|||.:::         ::||  .|..:...:.|........::|
 Worm   273 ITMADEHRHDIAELYTKITLGEMR---------RSLPHFNWPLFFNRMFKDLHEKNGKRITFDDN 328

  Fly   472 -----------QNLTIITSQADITYLQNIVEYLDDTPASHIESYLFLSTIEEL-------VLHTS 518
                       :.|.::..|.|...:.|.:|:          .:.|.:.:.:|       :....
 Worm   329 TEVVVYGYEFLRRLDVLIPQYDNRLIVNYLEW----------CWFFKTMLRDLPDPFALTIFKFY 383

  Fly   519 SSMRLLHSEYMRVAIGTEGSTPRSLYCANGVNSLLGMAVSYVLADADFTKEKLPKVERMLSDIRR 583
            .::.:::.:.:|    ..|       |...:|||:.||.|.:.....|..|...:||.|:|.|..
 Worm   384 KTLNIMNVQKVR----WHG-------CVTRINSLMPMATSAIYVKNHFDHEAKQQVEEMISLIME 437

  Fly   584 SFDRLVKSTSWMDAATKRKTIQKSAEMKSFIGFPPWLRNASVLNAYYEGAEVNASTHLENLMDFV 648
            ||..|:.|..|:...||:...||..|||..||:|.:|.:.:.:|..|:..:|....:.:....|.
 Worm   438 SFVDLLLSEDWLTKETKQTAKQKVNEMKRKIGYPDYLNDPAAVNNEYKTFKVYPGHYYQTKFSFY 502

  Fly   649 HWQMMDKLNE----MDKPEPIGWATSPSNVNAFHTFQSNAITVPIAILQYPFYDLGL-EALNYGS 708
            .....|.|..    :|:..   |....:.||||::..:|.|..|..|||..||.... .::|:|.
 Worm   503 EQYQRDVLERITEAVDRER---WVAGAALVNAFYSPNTNEIIFPAGILQPVFYSKDFPSSMNFGG 564

  Fly   709 IGTILGHELTHGFDDSGRRFDRAGNMVEWWSNRTIDEYVNRTECFVEQYSRYHLADIDEYIDGEL 773
            ||.::|||:||||||.||.:|..||:.:||.|.||.::.::.:|..:|||.|.|..|:..|:|:.
 Worm   565 IGVVIGHEITHGFDDRGRLYDNLGNIRQWWDNATISKFEHKAQCIEKQYSSYVLDQINMQINGKS 629

  Fly   774 TLGENIADNGGMREAFYAYRLYVKEVGRERSKLPGLEHYSHEQLFFISFGNLWCETYT-PAASRY 837
            |.|||||||||:::|:.||:.|.|...|. .:|||: :.:|:||||:::..:||.|.. ..|.|.
 Worm   630 TKGENIADNGGLKQAYRAYKKYEKRHSRP-PRLPGV-NLTHDQLFFLNYAQIWCGTMNDKEAIRK 692

  Fly   838 ALTDSHCPGQMRLRGVLSNSEEFARTFKCARGTPMNPDQPKCRIW 882
            ..|..|.||.:|::|.||||.:||:.:.|..|:.||| :.|||:|
 Worm   693 LRTSEHSPGPIRVKGPLSNSYDFAKAYNCEPGSQMNP-REKCRVW 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	PepO	146..882	CDD:226118	216/782 (28%)
		M13	151..880	CDD:189000	213/775 (27%)
nep-2	NP_494343.2	PepO	61..736	CDD:226118	218/790 (28%)
		M13	73..734	CDD:189000	213/776 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4162
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D157132at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.870