Protein Alignment Nep5 and nep-6

DIOPT Version :10

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_494537.1
• Gene: nep-6 / 184628
• WormBaseID: WBGene00017550
• Length: 726
• Species: Caenorhabditis elegans
• Alignment Length: 861
• Identity: 175/861 - (20%)
• Similarity: 319/861 - (37%)
• Gaps: 235/861 - (27%)

  Fly   105 LLALVIILLIAIIVISLGLK------------------------------------------KSS 127
            |:..:|.||..||::.|..|                                          |..
 Worm    18 LVLTIIALLATIIIMKLNEKPVEPPRVAPIAQKLVAPEKKSRPEPVTNPVTMTRPEPVTQASKPR 82

  Fly   128 SICRSKECLRTAASLIYAMDEQTDPCEDFYQFTCGRWANEHPRPDSVTSNDWFRERQAHIMRVVR 192
            ::|.:..|:..|..|:...|...|||:|||:..||:: :||.     .:|...:::...|.|:::
 Worm    83 NVCETPGCVTLADQLLNFQDPSVDPCQDFYKAACGKY-SEHE-----VANRRLQKKDIIIQRMIK 141

  Fly   193 EFLRSNITKSEPEAVGKAKTMYRACMDTKLLDKRDLEPLINYLLRFGLPVLPSALNLTLGSGSKY 257
            .||..|.| ||.::....:.:||.|...|      .|.:.|..::       :|.........|.
 Worm   142 NFLLKNET-SESKSENVMRQVYRTCEGLK------NEEIFNANMK-------TAFRELFKDIQKI 192

  Fly   258 ATEAANVKYNWLQSIVSIKQHLTMDLIIG------FDVFPD--PFNRTINRIALGTPETDSAFPF 314
            .:..|..| ||.::.:::.:.|...:.:|      |.:.|.  ||......:| .:|:..:.|
 Worm   193 GSWPAADK-NWDETKLNLNEMLLNIVKLGSSNFGLFQIRPTEVPFLEVAPDMA-RSPKVSANF-- 253

  Fly   315 NNDDSHKMLRKIHRKTIF--MQNSDDEDDSEDDRESEEEEAAKQTSTGMTAYLHYVRKV------ 371
                         ::.||  ::.:..:.|.....:..|:....:.:....||.:...||
 Worm   254 -------------QQIIFDILEKNGLQPDENVIADDVEDYITLEETLSQYAYDYNAEKVQFSKLQ 305

  Fly   372 -------IEKYLLYVDPNVNQEEATLGITELVKQGVRVARKVHEFKEEAENMTK-----PSKNPA 424
                   :||   .::..:|.....|.:|::..:  .||.|...|.:|..|:.|     |.:..|
 Worm   306 AQVPSLKLEK---IIEEMMNPNRKKLLVTKVKPR--MVAHKHSLFFDEKMNLEKLLKSTPKRTLA 365

  Fly   425 DDIVYITLQDLQNQTDKNIAPKTLPIWVRYMELILKGTRHAGNIQMTQNLTIITSQADITYLQNI 489
            :.:::.                       ||:..:.|.....|:...:|...:           :
 Worm   366 NYLIFY-----------------------YMDHAMNGLSVHDNVIKKRNCEKL-----------V 396

  Fly   490 VEYLDDTPASHIESYLFLSTIEELVLHTSSSMRLLHSEYMRVAIGTEGSTPRSLYCANGVNSLLG 554
            :|||                       ..:|:|
 Worm   397 IEYL-----------------------PKASLR-------------------------------- 406

  Fly   555 MAVSYVLADADFTKEKLPKVERMLSDIRRSFDRLVKSTSWMDAATKRKTIQKSAEMKSFIGFPPW 619
                 |.....|.|..|..|:.|..:.::||..:::.::|:.|.:|:..|.|..:|...||:|..
 Worm   407 -----VFVRNHFEKGNLKIVDEMAEETKKSFIEMLQESTWLGADSKKNAILKLEKMGKMIGYPKE 466

  Fly   620 LRNASVLNAYYEGAEVNAST------------HLENLMDFVHWQMMDKLNEMDKPEPIGWATSPS 672
            ......|:..:|..::....            |:|..::||..:     ..||...|:      .
 Worm   467 FEKKGALDKMFETLKLLPKDTLYGILKKIGRFHMEQGIEFVALE-----TPMDPVLPV------L 520

  Fly   673 NVNAFHTFQSNAITVPIAILQYPFYDLGL-EALNYGSIGTILGHELTHGFDDSGRRFDRAGNMVE 736
            ..|||:| ..|.::..:..:..|.:|... :.:|....|.||.||.:||||.:|.:.|..|.:..
 Worm   521 MTNAFYT-DRNHLSFLVGYMDDPLFDATYPKYVNIALTGNILAHETSHGFDTAGIKRDENGEVRS 584

  Fly   737 WWSNRTIDEYVNRTECFVEQYSRYHLADIDEYIDGELTLGENIADNGGMREAFYAYRLYVKEVGR 801
            |.....:.||..:|:|.|:||:.|......:.::|..||.|.:||..|:.   .|::::.|....
 Worm   585 WMKPEDLKEYGKKTQCLVDQYNEYDDPVFGKNLNGTTTLNEMVADMIGVT---VAWKVFEKLDSS 646

  Fly   802 ERSKLPGLEHYSHEQLFFISFGNLWCETYTPAASRYALTDSHCPGQMRLRGVLSNSEEFARTFKC 866
            :..|:.|.|:.:.::|:|.:....:|......:....||..|..|..|:.|:.||..:||..|.|
 Worm   647 KEQKVIGFENENIDKLYFRAAALDFCSLPPTTSLVEELTRVHPTGNFRVNGIFSNMPQFATAFNC 711

  Fly   867 ARGTPMNPDQPKCRIW 882
            ..|:|||| :.:|.|:
 Worm   712 PEGSPMNP-KTRCSIF 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	M13	151..880	CDD:341056	159/769 (21%)
nep-6	NP_494537.1	M13	105..724	CDD:341056	159/770 (21%)