Protein Alignment Nep5 and nep-4

DIOPT Version :10

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_509156.2
• Gene: nep-4 / 183746
• WormBaseID: WBGene00016896
• Length: 437
• Species: Caenorhabditis elegans
• Alignment Length: 349
• Identity: 75/349 - (21%)
• Similarity: 121/349 - (34%)
• Gaps: 131/349 - (37%)

  Fly   629 YYEGAEVNASTHLE-NLMDFVH--WQMMDKLNEMDK--PEPIGWATSPSNVNAFHTFQSNAITVP 688
            :|:|.......|:| |:.|.::  .|||:.:.|:..  .|...|..: :|:.......:|||.:|
 Worm   116 FYDGMLQPLYYHVEANVTDGINEIHQMMEDMVELGNIWLEKTPWVIN-NNLTEEMKNITNAIKMP 179

  Fly   689 IAILQYP--------------------------------FY---------------DLGLEA--- 703
            :::.:|.                                ||               |.|..|
 Worm   180 VSLTKYTNFIYNLLSPIETDFLNCVSEFEGIQNNTLFCLFYSAKIFVRTRGSYFIDDNGYNAEGT 244

  Fly   704 -----LNY-------------GSIGTILGHELTHGFDDSGRRFDRAGNMVEWWSNRTIDEYVN-- 748
                 .||             |..||.:|||:.|.|                     |:..:|
 Worm   245 IYFGFPNYYHTTYGNWRASKLGYTGTRVGHEIGHTF---------------------IEHSINPD 288

  Fly   749 --------RTECFVEQYSRYHLADIDEYIDGEL---------TLGENIADNGGMREAFYAYRLYV 796
                    ..:|...||    |...:||.:||:         |..:|.||..|::   .||.:..
 Worm   289 GLPYFSKPAEDCVQNQY----LKTCNEYYEGEVPDACNTSDYTFDDNGADVFGLQ---LAYAILE 346

  Fly   797 KEVGRE-RSKLPGLEHYSHEQLFFISFGNLWCETYTPAASRYALTD-SHCPGQMRLRGVLSNSEE 859
            :::..: |.:..||: .::|||.|.||...:|.     .|:...|| ||....:|:..| :....
 Worm   347 RDLSDQLREQADGLK-ITNEQLLFYSFAYRFCR-----GSKSNTTDGSHSHHNVRINAV-AQMPG 404

  Fly   860 FARTFKCARGTPMNPDQPK-CRIW 882
            |.:.|.||..:.|.....| |.|:
 Worm   405 FQQAFNCASDSRMMKSATKQCVIY 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	M13	151..880	CDD:341056	73/345 (21%)
nep-4	NP_509156.2	GluZincin	250..425	CDD:472708	50/209 (24%)