Protein Alignment Nep5 and nep-22

DIOPT Version :9

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_509528.1
• Gene: nep-22 / 181144
• WormBaseID: WBGene00020788
• Length: 798
• Species: Caenorhabditis elegans
• Alignment Length: 877
• Identity: 192/877 - (21%)
• Similarity: 336/877 - (38%)
• Gaps: 201/877 - (22%)

  Fly   104 GLLALVIILLIAIIVISLGLKKS---------------SSICRSKECLRTAASLIYAMDEQTDPC 153
            |.|.|.||:|..:..::..:..:               .::..|....:.|..|:..:|:..|||
 Worm    22 GSLVLNIIILGNVNTLTTTVNNNPVYHYTPAPQVNSTPGTVNTSPSYTQAANYLLNGLDDTVDPC 86

  Fly   154 EDFYQFTCGRWANEHP-----RPDSVTSNDWFRERQAHIMRVVREFLRSNITKSEPEAVGKAKTM 213
            :|||.|||.::.....     |....|.:....:..:.|:..:.:...::.|.|:.|.:.||  .
 Worm    87 QDFYAFTCNKFLQNTDLQKLGRSRLGTYDQAQVDVYSEIVAALSKIDVTSTTTSKTERITKA--A 149

  Fly   214 YRAC-------MDTKLLDKRDLEPLINYLLRFGLPVLPSALNLTLGSGSKYATEAANVKYNWLQS 271
            :..|       .|...:...::..|...:..||.|:                  ..||.| |:.:
 Worm   150 FETCKNNLASPADKTAVVYAEITSLFGGVPFFGEPL------------------KTNVDY-WMVA 195

  Fly   272 IVSIKQHL--TMDLIIGFDVFPDPFNRTINRIALGTPETDSAFPFNNDDSHKMLRKIHRKTIFMQ 334
            ....::|.  |:...|....:.|   .|.|.:..|.|....|            |..:.|..::
 Worm   196 GQIEQKHAVGTLTYTIASSDYKD---HTKNALYTGPPGLSLA------------RDFYVKPQYI- 244

  Fly   335 NSDDEDDSEDDRESEEEEAAKQTSTGMTAYLHYVRKVIEKYLLYVDPNVNQEEATLGITELVKQG 399
                         :|..:.....:..:||:.:..:|           ||..:.......|:|...
 Worm   245 -------------AEVNQRVSDVNDLLTAFANAAKK-----------NVGADALLAAAQEVVNFE 285

  Fly   400 VRVARKVHEFKEEAENMTKPSKNPADDIVYITLQDLQNQTDK-NIAPKTLPI----WVRYMELIL 459
            |::|                ..:..||:    |::.|.|.:. |||..|...    |..|:..:.
 Worm   286 VQIA----------------MASWPDDL----LRNYQQQYNPYNIASATTAYRAINWKSYLGQLF 330

  Fly   460 KGTRHAGNIQMTQNLTIITSQADITYLQNIVEYLDDTPASH---IESYLFLST-------IEELV 514
            .|.....: |...|: ::|..:...:|.::.    |...|:   :.:|:....       |....
 Worm   331 HGVASDAD-QANYNI-VVTEPSYFAWLNSVF----DGKTSNSTVVANYMIAQLLADESDFINPAT 389

  Fly   515 LHTSSSMRLLH--------------SEYMRVAIG--TEGSTPRSLYCANGVNSLLGMAVSYVLAD 563
            ...||....:|              .||....:.  :||       |.:.:.:.:.....||...
 Worm   390 AKVSSDTNYIHYALRNGRGIKKIGKREYRMADLDGISEG-------CMDLLTAYMPYGTGYVYVK 447

  Fly   564 ADFTKEKLPKVERMLSD----IRRSFDRLVKSTSWMDAATKRKTIQKSAEMKSFIGFPPWL---- 620
               :|.:..||:..:.|    |..:|..::.|.:|||..:|.:...||..:....|:|..:
 Worm   448 ---SKSERNKVQADVKDQTTLIINNFQGMIDSLNWMDTFSKNRAHNKSDSLVKNFGWPEAMFGDF 509

  Fly   621 RNASVLNAYYEGAEVNASTHLENLMDFV--------HWQMMDKLNEMDKP-EPIGWATSPSNVNA 676
            .:.:.::||.:........:.::..|..        ..::.:....|.:| :...:..||:.|||
 Worm   510 NDFTTVDAYNQDYASIIDLYTKDKNDIYGIFAVLKKGMEVREFFRIMGEPADRTNFLQSPAMVNA 574

  Fly   677 FHTFQSNAITVPIAILQYPFYDLGL-EALNYGSIGTILGHELTHGFDDSGRRF-------DRAGN 733
            ::..:.|:||.|.|....|:|:|.. :|.|:...|...|||||||:||.|.:|       |.:.|
 Worm   575 WYQPERNSITFPYAAWNPPYYNLNYPQAYNFAGQGGTGGHELTHGYDDEGVQFGFNGELTDCSWN 639

  Fly   734 MVEWWSNRTIDEYVNRTECFVEQYS---------RYHLADIDEYIDGELTLGENIADNGGMREAF 789
            ...|....:...:::..:|.|.|:|         ..|.|      :|..|.||||||.||.:.|:
 Worm   640 KCGWMDTNSSSGFIDMAQCVVTQFSTQCCPEKTGNIHCA------NGATTQGENIADLGGQQAAY 698

  Fly   790 YAYRLYVKEV--GRERSKLPGLEHYSHEQLFFISFGNLWCETYTPA-ASRYALTDSHCPGQMRLR 851
            .:||.||...  |.|..:|||||:|:..|:|:|::|..||...:.| .....||:.|.|.|.|..
 Worm   699 RSYRQYVATTRKGVEEDRLPGLENYTPNQIFWITYGYSWCMKQSDANLVHQLLTNPHSPAQCRTN 763

  Fly   852 GVLSNSEEFARTFKCARGTPMNPD-QPKCRIW 882
            .|:.:..||.:.|.|.||:||.|: ..:|::|
 Worm   764 QVMQDIPEFGKDFGCVRGSPMYPEPSGRCKVW 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	PepO	146..882	CDD:226118	182/818 (22%)
		M13	151..880	CDD:189000	180/811 (22%)
nep-22	NP_509528.1	PepO	76..795	CDD:226118	182/821 (22%)
		M13	83..793	CDD:189000	180/812 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4162
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.870