Protein Alignment Nep5 and nep-16

DIOPT Version :9

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_001023203.2
• Gene: nep-16 / 177541
• WormBaseID: WBGene00018472
• Length: 868
• Species: Caenorhabditis elegans
• Alignment Length: 899
• Identity: 162/899 - (18%)
• Similarity: 328/899 - (36%)
• Gaps: 283/899 - (31%)

  Fly    52 SGNGNATANGHGQNSAT---ESANGKQLPYEPISPNLIGIQSKFRRSYYHK--------VVLGGL 105
            ||:.|.      .|..|   |:.:.:::.: ||:|            :|.:        :.||.|
 Worm   156 SGDDNL------DNRLTQQLEAPSDRRIIF-PITP------------FYRRKGTCSKCSIWLGAL 201

  Fly   106 LALVIILLIAIIVI---------SLGLKKSSSICRSKECLRTAASLIYAMDEQTDPCEDFYQFTC 161
            .||..:|.||:.::         ::| .||:::|.:::|:..|..|...:|::.:|||:||:::|
 Worm   202 CALFFLLSIALFLVWVITTDGFRTIG-AKSTNVCNTRQCIDIAFRLSSCIDDEIEPCENFYRYSC 265

  Fly   162 GRWANEHPRPDSVTSNDWFRERQAHIMRVVREFLR--SNITKSE------PEAVGKAKTMYRACM 218
            .|:       .|.|::    ::.:.:.::..|.||  .::..||      |::...::::|.|||
 Worm   266 QRY-------HSQTAD----KQMSFLSQLKDESLRRMHSLLSSEEDSRLLPKSARLSRSLYSACM 319

  Fly   219 DTKLLDKRDLEPLINYLLRFGL-PVLPSALNLTLGSGSKYATEAANVKYNWLQSIVSIKQHLTMD 282
            :..|........|:.::..|.. |:|....|....|            |:|       ::|..|
 Worm   320 NAVLRSSNAPTDLLTFIRNFPCGPLLRDCQNFHADS------------YSW-------ERHAGM- 364

  Fly   283 LIIGFDVFPDPFNRTINRIALGTPETDSAFPFNNDDSHKMLRKIHRKTIFMQNSDDEDDSEDDRE 347
                .|.:...:|..:.                                      |.|....||
 Worm   365 ----LDWYAGRYNLIVY--------------------------------------DRDVHPQDR- 386

  Fly   348 SEEEEAAKQTSTGMTAYLHYVRKVIEKYLLYVDPNVNQEEATLGITELVKQGVRVARKVHEFKEE 412
                                     .|.:|.:.|.        .:|.:|  |:        .:.:
 Worm   387 -------------------------SKIILQIKPP--------DLTPIV--GL--------IERD 408

  Fly   413 AENMTKPSKNPADDIVYITL-----------------QDLQNQTDKNIAPKTLPIWVRYMELILK 460
            ..::.:||....:.::.::|                 :|:|:|.|: :|...:.:::...:
 Worm   409 LIDLARPSPTEFEPLLQLSLRQNLLSAFARDSLLRDPRDVQSQLDE-VARLMVDLYISARQ---- 468

  Fly   461 GTRHAGNIQMTQNLTIITSQADITYLQNIV--EYLD----------DTPASHIESYLFLSTIEEL 513
                  :..:|.|.|.:|.......|..:.  |:||          :|....|:.|.:.:.:.::
 Worm   469 ------SASLTPNTTYMTIGEMFQALPQLYLREFLDAQLSNTYRWTETDMLSIQDYDYFARLSDI 527

  Fly   514 VLHTSSSMRLLHSEYMRVA----IGTEGSTPRSLY----CANGVNSL-LGMAVSYVLADADFTKE 569
            :..||   |...:.|:...    :.....:||..|    |.:.::|. :|..: ||  |......
 Worm   528 MAQTS---RQAVANYLLTVTVWNLKQYSYSPRDQYGWRECVDQISSFEIGRKM-YV--DKASQTI 586

  Fly   570 KLPKVERMLSDIRRSFDRLVKSTSWMDAATKRKTIQKSAEMKSFIGFPPWLRNASVLNAYYEGAE 634
            .|||::..|.:::..|..:.:|       |..:.:.....:..::|||..|:|..::........
 Worm   587 DLPKIQEFLQNLKIDFLSVHRS-------TPLQYLSNINRLGFYVGFPRRLQNEELIWKPVSQVS 644

  Fly   635 VNASTHLENLM-------DFVHWQMMDKLNEMDKPE-PIGWATSPSNVNAFHTFQSNAITVPIAI 691
            :|.:.:.::::       |:...|:...|:..|... ||...|...|.|.      .||.:|:|.
 Worm   645 LNETDYFDSMIRVGKAERDYTMSQIGTYLDNDDTTTFPISDPTMLYNSNV------GAIVIPLAF 703

  Fly   692 LQYPFYDLGLEALNYG---SIGTILGHELTHGFDDSGRRFDRAGNMVEWWSNRTIDEYVNRTECF 753
            ::.|.|..|.|...||   |:|......::..|                |..  :|: .::.||.
 Worm   704 IEPPIYLPGDEVPMYGIYSSLGITTLQMISKVF----------------WQG--LDK-TSQLECL 749

  Fly   754 VEQYSRYHLADIDE--YIDGELTLGENIADNGGMREAFYAYRLYVKE--VGRERSKLPGLEHYSH 814
            ...:..:..|:...  .|:.||.....:||  ..:.|.|:|..:..:  :..|:: ||..:....
 Worm   750 DNVFRGFLDANRQRSPNIEPELLATIELAD--AFKSALYSYAKWQNDHHIHHEKT-LPAFDSTDS 811

  Fly   815 EQLFFISFGNLWC--ETYTPAASRYALTDSHCPGQMRLRGVLSNSEEFARTFKC 866
            .:...::|..::|  |...|.:...|:.::          |..||..|:..|.|
 Worm   812 MRSLMLTFSTMFCSGEGSEPGSDYEAMINT----------VAENSRMFSIHFNC 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	PepO	146..882	CDD:226118	137/785 (17%)
		M13	151..880	CDD:189000	136/780 (17%)
nep-16	NP_001023203.2	GluZincin	254..>725	CDD:387391	107/617 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010