Protein Alignment Nep5 and nep-26

DIOPT Version :9

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_001022540.1
• Gene: nep-26 / 174593
• WormBaseID: WBGene00014171
• Length: 807
• Species: Caenorhabditis elegans
• Alignment Length: 941
• Identity: 232/941 - (24%)
• Similarity: 392/941 - (41%)
• Gaps: 227/941 - (24%)

  Fly    31 LQRLQTPGNLSLLSAPIRANGSGN-------------GNATANGHGQNSATESANGKQLPYEPIS 82
            |::||..     ||..:|:..|.|             .|..:...|:.:::........|....|
 Worm     5 LEKLQRS-----LSHEMRSYSSLNPLLPSEDTPIQSFSNGVSLEEGKQASSSLLRDTGQPSSSRS 64

  Fly    83 PNLIGIQSKFRRSYYHKVVLGGLLALVIILLIAIIVISLG----LKKSSSICRSKECLRTAASLI 143
            ...|...||            |.|.|.::::...:.:|..    |...:..|.|:||:.||:.|:
 Worm    65 KEAISSSSK------------GCLLLTVLVIFLFVTLSFAIACFLYYQTLPCTSEECVMTASRLL 117

  Fly   144 YAMDEQTDPCEDFYQFTCGRWANEHPRPDSVTSNDWFR-ERQAHIMRVVREFLRSN------ITK 201
            ..:|:..:||::||||.||.|.|:.......:.|..:. :|.|| .::|:...:.|      .|.
 Worm   118 KRVDQSVEPCDNFYQFACGGWINQSVNLKYDSWNTLYETQRTAH-DQIVQAMHKINDGSYPLPTN 181

  Fly   202 SEPEAVGKAKTMYRACMDTKLLDKRDL---EPLINYL---------------------------- 235
            :...|..|   ||..||||..|::..|   |..::.|
 Worm   182 AGERAAAK---MYEQCMDTDTLEQTGLHLWERFVDELGGWMPELKNGALEQEESFEIELDEDEKK 243

  Fly   236 -LRFGL-PVLPSALNLTLGSGSKYATEAANVKYNWLQSIVSIKQHLTMDLIIGFDVFPDPFNRTI 298
             .||.: .::.||.|.     |.:....|.|:.|:|.|    |:|    ||..::..|
 Worm   244 RRRFEIEDIILSAFNY-----SVFPLFWAGVEVNYLNS----KEH----LITIYEQLP------- 288

  Fly   299 NRIALGTPETDSAFPFNNDDSHKMLRKIHRK------TIFMQNSDDE------DDSEDDRESEEE 351
               .|..||   .:.:|.:.:.:|   |:.|      |..:|...:|      .||.|::
 Worm   289 ---ILLAPE---KYHYNKELTPEM---IYGKMEGPPVTRALQQVGEELSAVLGFDSTDEK----- 339

  Fly   352 EAAKQTSTGMTAYLHYVRKVIEKYLLYVDPNVNQEEATLGITELVKQGVRVARKVHEFKEEAENM 416
                            ||.:|.. ::|::..:....:|.                  :||:.|..
 Worm   340 ----------------VRMMIAN-MIYLEYQITMAGSTF------------------YKEKKERY 369

  Fly   417 TKPSKNPADDIVYITLQDLQNQTDKNIAPKTLPIWVRYMELILKGTRHAGNIQMTQNLTIITSQA 481
            |           .:.|::||     .|||..  .|..::..::     ..|:..::.:.:.|...
 Worm   370 T-----------VVMLRELQ-----EIAPAI--NWHYFLSRLV-----GENLSHSEPIALKTGTQ 411

  Fly   482 DITYLQNIVEYLDDTPA--SHIESYLFLSTIEELVLHTSSSMR--LLHSEYMRVAIGTEGSTPRS 542
            .|..|..|||.|..:.:  :.:::|:...||...:.:.|...|  ||   :|.|::.:..::.|.
 Worm   412 WIPILSAIVEKLKQSRSGVAVLKNYVKWKTIMFHLAYASPKCRDGLL---WMAVSLYSGAASQRK 473

  Fly   543 LYCANGVNSLLGMAVSYVLA---DADFTKEKLPKVERMLSDIRRSFDRLVKSTS-WMDAATKRKT 603
            .:|...::.:..:::..:|.   ..|.|::.:..|:.:...|:..::.:|:|:: :.|..|:...
 Worm   474 EFCVLRLSGIFPLSLPSILRKIDGIDHTEKNVKAVQNIADRIQEKYEEMVRSSNLFSDRETRENV 538

  Fly   604 IQKSAEMKSFIGFPPWLRNASVLNAYYEGAEVNASTHLENLMDFVHWQMM--------DKLNEMD 660
            |.|...|..|||||..:|:.      ||..:.....|     |.:.|.|:        ::|..:.
 Worm   539 IDKVNNMTKFIGFPDAMRSD------YEMEKEAVRLH-----DTLFWSMVLGSSSVYKERLQRLR 592

  Fly   661 KP-EPIGWA-TSPSNVNAFHTFQSNAITVPIAILQYPFYD-LGLEALNYGSIGTILGHELTHGFD 722
            .| :|..|. |.|:.....|.::.|.:.:|...|:.|:.| ..|:..||..||||:||||||.||
 Worm   593 LPVDPRSWVDTRPAISVPAHNYERNLVQIPFDSLRLPYADEHQLDFANYAGIGTIIGHELTHAFD 657

  Fly   723 DSGRRFDRAGNMVEWWSNRTIDEYVNRTECFVEQYSRYHLADIDEYIDGELTLGENIADNGGMRE 787
            ..|:.....||:..|||..:|.|:..|.:|||:||:  .|.|..:....:..|.|||||..|::.
 Worm   658 GQGKLHGPTGNLGVWWSTDSIREFKAREQCFVKQYA--GLMDSHDMNAAKEGLYENIADQVGLKV 720

  Fly   788 AFYAYRLYVKEVGRERS-KLPGLEHYSHEQLFFISFGNLWCETYTPAASRYALTDSHCPGQMRLR 851
            |:.|:    |..|.:.| ::||||.||.:||||:::...||..   .:..|.| ..|...::|:.
 Worm   721 AYEAW----KSNGNQNSGRMPGLEKYSQDQLFFLAYTQGWCAL---RSKSYKL-QPHMEERIRML 777

  Fly   852 GVLSNSEEFARTFKCARGTPMNPDQPKCRIW 882
            |.|.||.|||..:||:..:.|||.. ||.||
 Worm   778 GSLQNSPEFASAWKCSSESFMNPPD-KCSIW 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	PepO	146..882	CDD:226118	203/807 (25%)
		M13	151..880	CDD:189000	201/800 (25%)
nep-26	NP_001022540.1	PepO	111..807	CDD:226118	206/816 (25%)
		M13	124..805	CDD:189000	201/801 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020