Protein Alignment Nep5 and nep-11

DIOPT Version :9

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_494538.1
• Gene: nep-11 / 173685
• WormBaseID: WBGene00017557
• Length: 848
• Species: Caenorhabditis elegans
• Alignment Length: 913
• Identity: 255/913 - (27%)
• Similarity: 419/913 - (45%)
• Gaps: 185/913 - (20%)

  Fly    64 QNSATESANGK---QLPYEPISPNLIGI-----QSKFR----RSYYHKVVLGGLL--ALVIILLI 114
            :||...:.:|.   ..|....:|::|.|     |..||    |:...|::|..||  .|:..:|:
 Worm    27 ENSDIPTPSGSPCFNAPARDEAPSVIFIPGKKFQGTFRWWKSRTTMEKLLLPVLLLFCLLTAVLL 91

  Fly   115 AIIV------------------------------------------------------ISLGLKK 125
            |:|:                                                      .|....|
 Worm    92 AVIINTDKRIEAMKTDHATQTEHAGFGDPTENPTKTAEDPRVPPIVPEAPTSPEPEVTTSTEKPK 156

  Fly   126 SSSICRSKECLRTAASLIYAMDEQTDPCEDFYQFTCGRWANEHPRPDSVTSNDWFRERQAHIMRV 190
            ...:|.:..|:|.|...:.||:...|||:||::|.||:|.::||.||.:.....|...:..:.:.
 Worm   157 EPEVCSTPGCVRAATHFLNAMNTSVDPCDDFFEFACGQWNDQHPIPDDMYGFGTFAYAREQVRQQ 221

  Fly   191 VREFLRSNITKSEPEAVGKAKTMYRACMDTKLLDKRDLEPLINYLLRFG-LPVLPSALNLTLGSG 254
            :|..|...:. :|.|::..|:..||:||:...||:....||...|...| .|:|....:.|
 Worm   222 LRVLLEQEVV-TESESINMARATYRSCMNKTQLDELMTGPLFETLTELGEWPLLQENWDKT---- 281

  Fly   255 SKYATEAANVKYNWLQSIVSIKQHLTMDLIIGFDVFPDPFNRTIN-------RIALGTPETDSAF 312
                      |:|:...:|:.::...:|:.....::.|..|.:.|       .:|||....|  :
 Worm   282 ----------KFNFTSLLVNSRRDYGVDVFFQLYIYADSKNTSRNTLFIDQSTLALGRGTRD--Y 334

  Fly   313 PFNNDDSHKMLRKIHRKTIFMQNSDDEDDSEDDRESEEEEAAKQTSTGMTAYLHYVRKVIEKYLL 377
            ..|.             |:|                         |:.||||..|:|::  .:||
 Worm   335 YLNT-------------TLF-------------------------SSHMTAYRKYLRQI--AHLL 359

  Fly   378 YVDPNVNQEEATLG--ITELVKQGVRVARKVHEFKEEAENMTKPSKNPADDIVY--ITLQDLQN- 437
            ..|.|:.:.|:.:.  |.:::...:.:| |:...::|..|.|:         :|  ..:|||.|
 Worm   360 KTDGNLTRSESEMNADIEKIIDFEIELA-KIIVAEDERRNNTR---------LYNKRQIQDLYNL 414

  Fly   438 --QTD-----KNIAPKTLP-IWVRYMELILKGTRHAGNIQMTQNLTIITSQADITYLQNIVEYLD 494
              |.|     ::|||..|. ::....|:|:                     .:|.|||::.|.::
 Worm   415 LPQVDWVPFFQSIAPSDLTHLFHNETEIII---------------------CEIEYLQHVSELIE 458

  Fly   495 DTPASHIESYLFLSTIEELVLHTSSSMRLLHSEYMRVAIGTEGSTPRSLYCANGVNSLLGMAVSY 559
            .|....:.:|:....::..|.:.......:..::::|..|.:.|.||...||...:::|.:|...
 Worm   459 KTDVGLLTNYVLWRVVQSNVRYLDERFEDIKQDFLKVMTGQQQSPPRWKDCAQVPSTVLPLAAGA 523

  Fly   560 VLADADFTKEKLPKVERMLSDIRRSFDRLVKSTSWMDAATKRKTIQKSAEMKSFIGFPPWLRNAS 624
            :...|.|.:....:..||:..:|.||..||:...|||..||...|:|:..|.:.||:|....:..
 Worm   524 IYVQAHFQESDKHEALRMIMHLRNSFADLVRQNDWMDEETKAVAIEKANSMINNIGYPDVTNDLP 588

  Fly   625 VLNAYYEGAEVNAS-THLENLMDFVHWQMMDKLNEMDKP-EPIGWATSPSNVNAFHTFQSNAITV 687
            .|:..|.|..::.| |:...:...|.|....:..::.|| :...:..||:.||||::.:.||||.
 Worm   589 KLDKQYLGLSISDSDTYYYIMKKSVVWMQSREFQKLTKPFDKHEFDISPAVVNAFYSPEKNAITF 653

  Fly   688 PIAILQYPFYDLGL--EALNYGSIGTILGHELTHGFDDSGRRFDRAGNMVEWWSNRTIDEYVNRT 750
            |..|||.||:. |.  :|:|||:||.::|||:||||||.|.::|:.||:..|||..:::.:..|.
 Worm   654 PAGILQPPFFS-GTFPKAVNYGAIGAVIGHEITHGFDDQGSQYDKDGNLHNWWSESSLNSFDTRR 717

  Fly   751 ECFVEQYSRYHLADIDEYIDGELTLGENIADNGGMREAFYAYRLYVKEVGRERSKLPGLEHYSHE 815
            .|.||||..|.:...:..::|:||.|||||||||::|||.||:.||.|.| |..:||||:.|::|
 Worm   718 RCIVEQYGNYTVPKTNFRVNGKLTQGENIADNGGVKEAFQAYQKYVTENG-EEPRLPGLQQYTNE 781

  Fly   816 QLFFISFGNLWC-ETYTPAASRYALTDSHCPGQMRLRGVLSNSEEFARTFKCARGTPMNPDQPKC 879
            |:||:|:.:.|| :....||.:..|||.|.|...|:.|||||.:.||..:||.|..|:|||. ||
 Worm   782 QIFFVSYAHFWCGKKKEAAAMQQVLTDEHSPEVFRVIGVLSNMQAFADVYKCPRNAPVNPDH-KC 845

  Fly   880 RIW 882
            .:|
 Worm   846 IVW 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	PepO	146..882	CDD:226118	228/761 (30%)
		M13	151..880	CDD:189000	226/754 (30%)
nep-11	NP_494538.1	PepO	174..848	CDD:226118	229/764 (30%)
		M13	181..845	CDD:189000	225/754 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D157132at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020