Protein Alignment Nep5 and nep-9

DIOPT Version :10

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_494531.2
• Gene: nep-9 / 173683
• WormBaseID: WBGene00017554
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 842
• Identity: 157/842 - (18%)
• Similarity: 292/842 - (34%)
• Gaps: 208/842 - (24%)

  Fly    88 IQSKFRRSYYHKVVLGGLLALVIILLIAIIVISLGLKK--SSSICRSKECLRTAASLIYAMDEQT 150
            :..:.|::....|||..|..::::.|..:.......|.  :...|.|.:|:..|..|....|..|
 Worm    20 VSLEIRKNEKFWVVLRILNGIIVVGLFTLYTFHFHSKSRVTPQFCESPQCIILAQELKAYSDTAT 84

  Fly   151 DPCEDFYQFTCGRWANEHPRPDSVTSNDWFRERQAHIMRVVREFLRSNITKSEPEAVGKAKTMYR 215
            ..|||||:.||..: .:|...|....   .::|:| :.::||.||:.:.:....|:....|.::.
 Worm    85 KSCEDFYKATCENY-KDHQALDRHRD---CKKRKA-VNKLVRGFLQRDESTFTSESESAIKLIFG 144

  Fly   216 AC----MDTKLLD-KRDLEPLINYLLRFGLPVLPSALNLTLGSGSKYATEAANVKYNWLQSIVSI 275
            .|    .:|..|| .:|::.:.::      |||                     ::||..|:.::
 Worm   145 KCDELSRNTSYLDIFKDIKKIGSW------PVL---------------------EHNWKDSMFNL 182

  Fly   276 KQHLTMDLIIGFDVFPDPFNRTINRIALGTPETDSAFPFNNDDSHKMLRKIHR--KTIF------ 332
            ...:...:.:|...| ..|...:.::|.|        .|....|.|..:.||:  |||.
 Worm   183 DDVIAKLVKLGSTDF-GLFKLELRKLAFG--------HFAVFVSSKQEQNIHQLEKTILGILKAN 238

  Fly   333 ------MQNSDDEDDSEDDRESEEEEAAKQTSTGMTAYLHYVRKVIEKYLLYVDPNVNQEEATLG 391
                  .:.|||..|..|.:...:|...::|         |:     :|.||....|.    .||
 Worm   239 GIQQDRKELSDDLKDYSDFKNHLKEFYQEET---------YI-----EYRLYAGSIVE----NLG 285

  Fly   392 ITELVKQGVRVARKVHEFKEEAENMTKPSKNPADDIVYITLQDLQNQTDKNIAPKTLPIWVRYME 456
            |:.|..|
 Worm   286 ISSLTTQ---------------------------------------------------------- 292

  Fly   457 LILKGT-----RHAGNIQMTQNLTIITSQADITYLQNIVEYLDDTPASHIESYLFLSTIEELVLH 516
            :.||.|     .|.....:..|.::...:.:     |:...:..||...:.::|....|:.:...
 Worm   293 MALKSTGLDVFNHVNQRTLITNSSLFFGEEN-----NLGMIIQKTPKRTLANFLIFHFIDVMTTD 352

  Fly   517 TSSSMRLLHSEYMRVAIGTEGSTPRSLYCANGVNSLLGMAVSYVLADADFTKEKLPKVERMLSDI 581
            .:::.:.                     |...:..||..|...||:.....::....:.:|..|:
 Worm   353 LANATKA---------------------CKETLIDLLPRASIQVLSRNFVNEDAQDDMVKMAQDL 396

  Fly   582 RRSFDRLVKSTSW-------MDAATKRKTIQKSAEMKSFIGFPPWLRNASVLNAYYEGAEVNAST 639
            :.....::.::.:       .||..::|.|||...:.....:|     ..||:..:|...:..|.
 Worm   397 KTKITEMIDNSPFFTKFHLVFDAEEQKKLIQKVKAIGIVTEYP-----QEVLDRDFERLNLTPSD 456

  Fly   640 HLENLMDFVHWQMMDKLNEMDKPEPIGWATSPSNV----NAFHTFQSNAITVPIAILQYPFYDLG 700
            .:...:     |.:.:|......|.:|....|::.    :|.:...:|.:|:...|:..|::|..
 Worm   457 SIYRTI-----QKLRRLRSEQLIEHLGGDLDPTDTRVWGSAHYDQTTNNLTIFAPIIDGPYFDTS 516

  Fly   701 L-EALNYGSIGTILGHELTHGFDDSGRRFDRAGNMVEWWSNRTIDEYVNRTECFVEQYSRYHLAD 764
            . ..:|...:|.|||.||....|....|.|..|....|....::..:....:|:.|:|.:    .
 Worm   517 YPNYVNQFLMGFILGRELGRSLDSVRIRKDEKGQTENWLKPESLKRFDEHLKCWAEKYDK----S 577

  Fly   765 ID---------EYIDGELTLGENIADNGGMREAFYAYRLYVKEVGRERSKLPGLEHYSHEQLFFI 820
            .|         ..|:|.....|..||..| .||  ::|.::|...:....|...:.....::||.
 Worm   578 ADPLKSESKGIRQIEGRYIQNEMFADFIG-HEA--SWRAFMKLDVKNEEVLETFKVIKLRRMFFN 639

  Fly   821 SFGNLWCETYTPAASRYALTDSHCPGQMRLRGVLSNSEEFARTFKCARGTPMNPDQPKCRIW 882
            .....:|...:.:....:..:.|.....|:.|...|..:||..|:||....||| |.||.::
 Worm   640 VQALYFCRPPSGSTDWLSYQEHHQHYSFRVNGAFKNMPQFALAFECASDDDMNP-QNKCSMF 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	M13	151..880	CDD:341056	142/773 (18%)
nep-9	NP_494531.2	GluZincin	87..698	CDD:472708	142/771 (18%)