Protein Alignment Nep5 and Nep2

DIOPT Version :10

• Sequence 1: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: XP_061497288.1
• Gene: Nep2 / 1281326
• VectorBaseID: AGAMI1_002834
• Length: 792
• Species: Anopheles gambiae
• Alignment Length: 859
• Identity: 234/859 - (27%)
• Similarity: 393/859 - (45%)
• Gaps: 172/859 - (20%)

  Fly    93 RRSYYHK------VVLG-GLLALVIILLIAII-------------------------------VI 119
            ||:...|      ||.| .::||:|.||..::                               |:
Mosquito    37 RRTALEKVLTLISVVCGVAVVALIISLLTVVLTDRIQSESSSSSAQPLTAGRRGKALNKHPNTVV 101

  Fly   120 SLGLKKSSSICRSKECLRTAASLIYAMDEQTDPCEDFYQFTCGRWANEHPRPDSVTSNDWFRERQ 184
            ..| |.:.:||.:..|:.:|:..:..||::.:||:|||.:.||::..|...||...|.:.|....
Mosquito   102 DSG-KSAENICLTPGCIHSASKALEQMDQEVEPCDDFYNYACGKFVKETVIPDEKVSVNTFSVIG 165

  Fly   185 AHIMRVVREFLRSNITKSEPEAVGKAKTMYRACMDTKLLDKRDLEPLIN-YLLRFGLPVLPSALN 248
            ..:.:.:|..:...|:.||......||.:|:.||:...::::.::||:: :.:..|.|||
Mosquito   166 DRLQQQLRSLVSEEISDSEATPFKLAKNLYKLCMNKTRIEEKGIKPLLDIHEVLGGWPVL----- 225

  Fly   249 LTLGSGSKYATEAANVKYNWLQSIVSIKQH-LTMDLIIGFDVFPDPFNRTINRIALGTPETDSAF 312
                .|..:..:::   ::|::|:...:.: .:.|....|.:..|..|.| .||.    :||.|
Mosquito   226 ----KGDSWDLDSS---WSWVKSVKDFRNNGYSTDYFFDFSIGSDLKNST-RRII----DTDQA- 277

  Fly   313 PFNNDDSHKMLRKIHRKTIFMQNSDDEDDSEDDRESEEEEAAKQTSTGMTAYLHYVRKVIEKYLL 377
              :...|.:.|.|.....|                             ::||.:|:
Mosquito   278 --SLGISREYLVKGMENPI-----------------------------VSAYYNYM--------- 302

  Fly   378 YVDPNVNQEEATLGITELVKQGVRVARKVHE---FKEEAENMTKPSK---------NPADDIVYI 430
             ||..|     .||..|     .|..|::.:   |:....|::.|::         ||      :
Mosquito   303 -VDMAV-----LLGADE-----ERAKRELLDSLNFEMALANISLPNEKRRNATALYNP------M 350

  Fly   431 TLQDLQNQ---TDKNIAPKTLPIWVRYMELILKGTRHAGNIQMTQNLTIITSQADITYLQNIVEY 492
            |:::.|.:   ||          |:.|...|||.|    .|.:.:...||.|..  |:::.:...
Mosquito   351 TVKEFQQRYPYTD----------WLEYFNAILKDT----GIVIGEEEVIIVSVP--TFMEQLGPL 399

  Fly   493 LDDTPASHIESYLF--LSTIEELVLHTSSSMRLLHSEYMRVAIGTEGSTPRSLYCANGVNSLLGM 555
            |.:||...:.:|:.  :|......|  :..:|....:|.....|.:...||...|.:..:..|.:
Mosquito   400 LQNTPKRVMANYVMWRISGFSSFFL--TEKLRKRQLQYSTALSGKQEQEPRWKECVDITSGSLPI 462

  Fly   556 AVSYVLADADFTKEKLPKVERMLSDIRRSFDRLVKSTSWMDAATKRKTIQKSAEMKSFIGFPPWL 620
            :|..:.....|.::.......|::||:..|..::|...|||..|:...::|.:.|.:.||:|..|
Mosquito   463 SVGALYIRKYFREDSKRAALDMVNDIKSVFVDILKKVDWMDEVTRVSALEKVSTMATHIGYPDEL 527

  Fly   621 RNASVLNAYYEGAEVNA-STHLENLM---DFVHWQMMDKL----NEMDKPEPIGWAT--SPSNVN 675
            .:.:.:..||:..|... ||:|..::   .|...:...||    |:.|      |.|  .|:.||
Mosquito   528 MDDAKIAEYYKDLEFQPDSTYLNTILYMNKFGTTKAFKKLRIAVNKTD------WITHSRPAIVN 586

  Fly   676 AFHTFQSNAITVPIAILQYPFYDLGL-EALNYGSIGTILGHELTHGFDDSGRRFDRAGNMVEWWS 739
            ||::...|:|..|..|||..|:.... :.:|||:||.::|||:||||||.||:||:.||:|:||.
Mosquito   587 AFYSSIENSIQFPAGILQGQFFSYDRPKYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDWWQ 651

  Fly   740 NRTIDEYVNRTECFVEQYSRYHLADIDEYIDGELTLGENIADNGGMREAFYAYRLYVKEVGRERS 804
            :.|...|:.:..|.:|||..|...::...::|..|.|||||||||::||:||||.:.::.|.|:
Mosquito   652 SDTKTAYLEKARCIIEQYGNYTEPNVKLNLNGINTQGENIADNGGIKEAYYAYRRWTEKNGPEQ- 715

  Fly   805 KLPGLEHYSHEQLFFISFGNLWCETYTPAASRYALTDS-HCPGQMRLRGVLSNSEEFARTFKCAR 868
            :|||| :.|.||:|::|....||..|.|...:..:|.. |.|||.|:.|.:||..|||:.|.|..
Mosquito   716 RLPGL-NLSPEQMFWLSAAQTWCSVYRPETMKMRITTGVHSPGQFRVLGPMSNMHEFAKDFNCPV 779

  Fly   869 GTPMNPDQPKCRIW 882
            |:||||:. ||.:|
Mosquito   780 GSPMNPEH-KCEVW 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep5	NP_733186.2	M13	151..880	CDD:341056	212/759 (28%)
Nep2	XP_061497288.1	None